CXCR6

  • Official Full Name

    Cxcr6 chemokine (C-X-C motif) receptor 6

  • Synonyms

    CXCR6; chemokine (C-X-C motif) receptor 6; C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; BONZO; STRL33; BB217514;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
  • Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Macaca mulatta (Rhesus macaque)
  • Macaca nemestrina (Pig-tailed macaque)
  • Mouse
  • Pan troglodytes (Chimpanzee)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CXCR6-2183H Recombinant Human CXCR6 Protein Wheat Germ N/A
Human CXCR6-2184H Recombinant Human CXCR6 Protein, GST-tagged Wheat Germ GST
Human CXCR6-7160HCL Recombinant Human CXCR6 293 Cell Lysate HEK293 N/A
Human CXCR6-2326HF Recombinant Full Length Human CXCR6 Protein In Vitro Cell Free System GST
Human CXCR6-301461H Recombinant Human CXCR6 protein, GST-tagged E.coli GST
Human CXCR6-2328HF Recombinant Full Length Human CXCR6 Protein, GST-tagged In Vitro Cell Free System GST
Human CXCR6-0289H Recombinant Human CXCR6 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CXCR6-0989H Active Recombinant Human CXCR6 Full Length Transmembrane protein(VLPs) HEK293 N/A
Mouse CXCR6-4112M Recombinant Mouse CXCR6 Protein Mammalian Cell His
Mouse CXCR6-2103M Recombinant Mouse CXCR6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CXCR6-2103M-B Recombinant Mouse CXCR6 Protein Pre-coupled Magnetic Beads HEK293
Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) RFL4351CF Recombinant Full Length Cercocebus Atys C-X-C Chemokine Receptor Type 6(Cxcr6) Protein, His-Tagged E.coli expression system His
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) RFL8430CF Recombinant Full Length Chlorocebus Aethiops C-X-C Chemokine Receptor Type 6(Cxcr6) Protein, His-Tagged E.coli expression system His
Homo sapiens (Human) RFL5105HF Recombinant Full Length Human C-X-C Chemokine Receptor Type 6(Cxcr6) Protein, His-Tagged E.coli expression system His
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL12183MF Recombinant Full Length Macaca Fascicularis C-X-C Chemokine Receptor Type 6(Cxcr6) Protein, His-Tagged E.coli expression system His
Macaca mulatta (Rhesus macaque) RFL5993MF Recombinant Full Length Macaca Mulatta C-X-C Chemokine Receptor Type 6(Cxcr6) Protein, His-Tagged E.coli expression system His
Macaca nemestrina (Pig-tailed macaque) RFL26611MF Recombinant Full Length Macaca Nemestrina C-X-C Chemokine Receptor Type 6(Cxcr6) Protein, His-Tagged E.coli expression system His
Pan troglodytes (Chimpanzee) RFL31199PF Recombinant Full Length Pan Troglodytes C-X-C Chemokine Receptor Type 6(Cxcr6) Protein, His-Tagged E.coli expression system His
Rhesus Macaque CXCR6-1116R Recombinant Rhesus monkey CXCR6 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CXCR6-941R-B Recombinant Rhesus Macaque CXCR6 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CXCR6-941R Recombinant Rhesus Macaque CXCR6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Kit-0880 ADK Assay Kit N/A
Kit-0879 dCK Screening Assay Kit N/A
Kit-1203 CXCR6 Total GPCR Internalization Assay Kit N/A
Kit-1204 CXCR6 HEK 293 β-Arrestin GPCR Assay Kit N/A
Kit-1205 CXCR6 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CXCR6 Related Articles
  • CXCR6 Related Gene Family
  • CXCR6 Related Research Area

CXCR6 involved in several pathways and played different roles in them. We selected most pathways CXCR6 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCR6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chemokine receptors bind chemokinesCCR6;CCR3;CXCL13;CCR7;CCR1;AMCF-II;CXCR6;ACKR4;CCL27
Chemokine signaling pathwayMAPK3;PLCB1;JAK3;CCL21;GNG7;Adcy4;XCL2;CXCL13;GNG13
Class A/1 (Rhodopsin-like receptors)OXGR1A.3;GPR55;OPN1MW;ADORA2A;OPN4B;GRP;ADRB3;ADRA1B;ZFPM2B
Cytokine-cytokine receptor interactionCXCR4;TNFRSF19;CCL8;IL18R1;Il4ra;BMP7A;XCL1;TNFRSF4;PF4
G alpha (i) signalling eventsADORA1;SOUL4;TAS2R7;OXER1;AGTR2;RGS10;OPN1SW1;CXCR7B;RGS6
GPCR downstream signalingNET1;TAS2R3;EDNRA;SSTR3;GPR4;ARHGEF18A;VIP;RAMP1;APLN
GPCR ligand bindingPTHLHA;PTHRP2;LTB4R;CHRM1;ANXA1;HCAR1-2;GPR55A;RLN3A;CXCL13
Peptide GPCRsTAC4;CX3CR1;CXCR6;SSTR4;SSTR1;SSTR5

CXCR6 has several biochemical functions, for example, C-X-C chemokine binding, C-X-C chemokine receptor activity, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCR6 itself. We selected most functions CXCR6 had, and list some proteins which have the same functions with CXCR6. You can find most of the proteins on our site.

Function Related Protein
C-X-C chemokine bindingCXCR3;CXCR7;HMGB1;CXCR6
C-X-C chemokine receptor activityCXCR7;CXCR3.1;CXCR5;CXCR6;CXCR4;CXCR4B;CCR9A;CXCR4A;CCBP2
G-protein coupled receptor activityCCR7;OLFR147;VMN2R116;OR2A42;OR8A1;TAAR14H;CCR12A;OLFCS1;BAI3
coreceptor activityRAMP2;HFE2;CXCR6;CXCR7;CXCR4;NRP1;RAMP1;CCR5;CD8B

CXCR6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCR6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCR6.

Wehr, A; Baeck, C; et al. Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury. PLOS ONE 9:-(2014).
Slauenwhite, D; Gebremeskel, S; et al. Regulation of Cytokine Polarization and T Cell Recruitment to Inflamed Paws in Mouse Collagen-Induced Arthritis by the Chemokine Receptor CXCR6. ARTHRITIS & RHEUMATOLOGY 66:3001-3012(2014).
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