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Official Full Name Cxcr6 chemokine (C-X-C motif) receptor 6
Synonyms CXCR6; chemokine (C-X-C motif) receptor 6; C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; BONZO; STRL33; BB217514;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CXCR6-301461H Recombinant Human CXCR6 protein, GST-tagged E.coli GST
    Human CXCR6-2183H Recombinant Human CXCR6 Protein Wheat Germ N/A
    Human CXCR6-2184H Recombinant Human CXCR6 Protein, GST-tagged Wheat Germ GST
    Human CXCR6-7160HCL Recombinant Human CXCR6 293 Cell Lysate HEK293 N/A
    Mouse CXCR6-4112M Recombinant Mouse CXCR6 Protein Mammalian Cell His
    Rhesus Macaque CXCR6-1116R Recombinant Rhesus monkey CXCR6 Protein, His-tagged Mammalian Cell His
    Kit-0879 dCK Screening Assay Kit N/A
    Kit-0880 ADK Assay Kit N/A
    Kit-1203 CXCR6 Total GPCR Internalization Assay Kit N/A
    Kit-1204 CXCR6 HEK 293 β-Arrestin GPCR Assay Kit N/A
    Kit-1205 CXCR6 CHO-K1 β-Arrestin GPCR Assay Kit N/A

    CXCR6 involved in several pathways and played different roles in them. We selected most pathways CXCR6 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCR6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine receptors bind chemokines AMCF-II; CX3CR1; CCRL2; CCL35.2; CXCL11.8; CCR3; CXCR6; CCR6; CCR5; CCL35.1
    Chemokine signaling pathway CXCL8; RHOA; FOXO3; GRK5; BRAF; AKT2; PARD3; GNAI3; SHC1; CCL17
    Class A/1 (Rhodopsin-like receptors) ADRB1; ADRA2B; RHOL; OXGR1A.2; OXGR1A.3; RLN3A; ADRA1D; SSTR1; CCR5; DRD5
    Cytokine-cytokine receptor interaction IL9; CTF1; ACVR1L; BMPR1AA; FAS; IL6; Ccl12; XCL1; VEGFAA; TNFRSF8
    G alpha (i) signalling events RGS14; CHRM2; S1PR5B; OXER1; OXGR1; RGS7; RLN3; POMCB; CCL35.2; ANXA1B
    GPCR downstream signaling HCAR1-2; TAE1; OXGR1A.1; CHRM4; ADM; NMS; PROKR1A; ARHGEF1A; CNR2; ANXA1A
    GPCR ligand binding HCAR1-2; UTS2D; PYYA; GPR39; OPN5; KISS1; EDNRB; OPN1LW; OPN1SW; CALCRL
    Peptide GPCRs TAC4; CXCR6; SSTR1; SSTR5; SSTR4; CX3CR1

    CXCR6 has several biochemical functions, for example, C-X-C chemokine binding, C-X-C chemokine receptor activity, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCR6 itself. We selected most functions CXCR6 had, and list some proteins which have the same functions with CXCR6. You can find most of the proteins on our site.

    Function Related Protein
    C-X-C chemokine binding HMGB1; CXCR7; CXCR6; CXCR3
    C-X-C chemokine receptor activity CXCR2; CXCR4A; CXCR3.1; CXCR7; CCR9A; CCBP2; CXCR4B; CXCR3; CXCR4; CXCR6
    G-protein coupled receptor activity GRM2; OR1L6; OLFR469; OPRL1; ADORA2AA; OLFR497; OR11A1; OPN4A; F2RL1.2; DRD2L
    coreceptor activity HFE2; RAMP1; CXCR7B; CD8A; PVRL2; CD86; RGMA; ZP2; ACKR3B; TMIGD2

    CXCR6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCR6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCR6.

    Wehr, A; Baeck, C; et al. Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury. PLOS ONE 9:-(2014).
    Slauenwhite, D; Gebremeskel, S; et al. Regulation of Cytokine Polarization and T Cell Recruitment to Inflamed Paws in Mouse Collagen-Induced Arthritis by the Chemokine Receptor CXCR6. ARTHRITIS & RHEUMATOLOGY 66:3001-3012(2014).

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