FXYD2
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Official Full Name
FXYD domain containing ion transport regulator 2 -
Synonyms
FXYD2;FXYD domain containing ion transport regulator 2;ATP1G1, HOMG2, hypomagnesemia 2, renal;sodium/potassium-transporting ATPase subunit gamma;MGC12372;sodium pump gamma chain;Na(+)/K(+) ATPase subunit gamma;ATPase, Na+/K+ transporting, gamma 1
Recombinant Proteins
- Rat
- Mouse
- Zebrafish
- Human
- Xenopus laevis
- Mammalian Cells
- HEK293
- E.coli
- Protein Conjugation
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Avi
- Fc
- GST
- DDK
- Myc
Involved Pathway
FXYD2 involved in several pathways and played different roles in them. We selected most pathways FXYD2 participated on our site, such as cGMP-PKG signaling pathway,cAMP signaling pathway,Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with FXYD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein digestion and absorption | CELA3B,PGA4,ATP1B4,DPP4,CPB2,COL24A1,ATP1A4,KCNJ13,ATP1B3,COL27A1 |
| Thyroid hormone synthesis | TSHR,Adcy4,GSR,ATP1B1,ITPR3,ASGR2,CREB3L3,PRKACB,PLCB2,PAX8 |
| Aldosterone-regulated sodium reabsorption | INSR,FXYD4,NEDD4L,ATP1A3,SFN,INS1,SLC9A3R2,PDPK1,PIK3R1,ATP1B2 |
| Adrenergic signaling in cardiomyocytes | ADRA1D,ATP1A1B,GNA15.1,CACNG1,CALM2B,SCN5A,AKT3A,ATP1B4,ATP1A4,CALML3 |
| Insulin secretion | ITPR3,PLCB1,PRKCG,PRKCB,VAMP2,SLC2A2,FFAR1,RIMS2,KCNMB4,CCKAR |
| Endocrine and other factor-regulated calcium reabsorption | ATP1A3,KLK1B11,KLK1B9,VDR,PRKACB,PRKCG,PRKACA,PRKCB,SLC8A1,ESR1 |
| Bile secretion | NR1H4,NCEH1,CA2,ADCY6,SLCO1B3,SLC9A1,NR0B2,AQP8,SCARB1,SLCO1A5 |
| cGMP-PKG signaling pathway | PIK3CB,BDKRB2,ATP1A4,MYLK3,VDAC1,PPP3CA,ATP2A2,KCNMB3,PRKCE,ATP2B4 |
| Proximal tubule bicarbonate reclamation | ATP1A4,CA2,MDH1,ATP1A3,Car4,ATP1B2,CA4,GLS2,ATP1B1,SLC4A4 |
Protein Function
FXYD2 has several biochemical functions, for example, ion channel activity,sodium channel regulator activity,sodium:potassium-exchanging ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FXYD2 itself. We selected most functions FXYD2 had, and list some proteins which have the same functions with FXYD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transporter activity | ATP5G1,SLCO1F1,APODA.2,SLC17A9B,ABCA6,SLC13A5,SLC22A1,AP1G1,LCN5,SLC2A15B |
| ion channel activity | GJD3,KCNA2B,TRPM1A,TRPC4A,SCN4AA,SCNN1G,TRPC4B,RYR1B,HTR3B,P2RX8 |
| sodium channel regulator activity | SCN1BB,SGK1,YWHAH,FGF13,SGK2A,RANGRF,GPD1L,SCN1BA,SCN1B,SCN2B |
| sodium:potassium-exchanging ATPase activity | ATP1B3,ATP4A,ATP1A2A,ATP1A1A.1,ATP1A1B,ATP1B2,ATP1A3,ATP1A1A.3,ATP1A3A,ATP1A4 |
Interacting Protein
FXYD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FXYD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FXYD2.
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References
- Hald, J; Galbo, T; et al. Pancreatic islet and progenitor cell surface markers with cell sorting potential. DIABETOLOGIA 55:154-165(2012).
- Silva, ECC; Masui, DC; et al. Identification of a crab gill FXYD2 protein and regulation of crab microsomal Na, K-ATPase activity by mammalian FXYD2 peptide. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1818:2588-2597(2012).
