IL15RA

  • Official Full Name

    interleukin 15 receptor, alpha chain

  • Overview

    This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and
  • Synonyms

    IL15RA; interleukin 15 receptor, alpha chain; interleukin-15 receptor subunit alpha; CD215; I15RA_HUMAN; IL 15R alpha; IL-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; Interleukin 15 receptor alpha; Interleukin 15 receptor subunit alpha; MGC104179; sIL-15 receptor subunit alpha; sIL-15R-alpha; sIL-15RA; Soluble interleukin 15 receptor subunit alpha; Soluble interleukin-15 receptor subunit alpha; OTTMUSP00000011997; OTTMUSP00000011998; OTTMUSP00000011999; OTTMUSP00000051896; OTTMUSP00000051897; OTTMUSP00000051898; OTTMUSP00000051899; OTTMUSP00000051901; OTTMUSP00000051907; IL-15 receptor subunit al; AA690181;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • CHO
  • CHO cells
  • E.coli
  • HEK293
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Mouse myeloma cell line
  • Sf21 Insect Cell
  • Wheat Germ
  • C
  • Fc
  • hFc
  • His
  • Avi
  • Fc|His
  • His (Fc)
  • Myc
  • His|HIgG
  • human|IgG1|Fc
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL15RA-530H Active Recombinant Human IL15RA protein, Fc/His-tagged Insect Cell Fc/His
Human IL15RA-051H Active Recombinant Human IL15RA protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi Ile31-Thr205
Human IL15RA-28598TH Recombinant Human IL15RA Wheat Germ N/A 100 amino acids
Human IL15RA-14151H Recombinant Human IL15RA protein, His-tagged E.coli His 1-231 aa
Human IL15RA-1655H Recombinant Human IL15RA protein, Fc-tagged HEK293 human/IgG1/Fc Ile31-Thr205
Human IL15RA-1653H Recombinant Human Interleukin 15 Receptor, Alpha, Fc-His Sf21 Insect Cell Fc/His
Human IL15RA-5247HCL Recombinant Human IL15RA Overexpression Lysate(Ile31-Asp96&Asn49-Ser162) HEK293 C-hFc Ile31-Asp96&Asn49-Ser162
Human IL15RA-5246HCL Recombinant Human IL15RA Overexpression Lysate(Ile31-Thr205) HEK293 C-hFc Ile31-Thr205
Human IL15RA-4379H Recombinant Human IL15RA protein, His&Myc-tagged E.coli His&Myc 31-205aa
Human IL15RA-225H Recombinant Human IL15RA Protein, hIgG-His-tagged Insect Cell His/HIgG 31-205aa
Human IL15RA-273H Recombinant Human IL15RA protein, His-Avi-tagged HEK293 His-Avi It contains Asp 21 - Glu 335.
Human IL15RA-273HB Recombinant Human IL15RA protein, His-Avi-tagged, Biotinylated HEK293 His-Avi It contains Asp 21 - Glu 335.
Human IL15RA-0269H Active Recombinant Human IL15RA protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Ile31-Thr205
Human IL15RA/IL15-81H Recombinant Human IL15RA/IL15 Complex Protein, Fc-tagged Human Cell Fc
Human IL15RA-2292H Recombinant Human IL15RA Protein, His-tagged E.coli N-His Ile31-Leu234
Human IL15RA-0267H Active Recombinant Human IL15RA protein, Fc-tagged, FITC-Labeled HEK293 Fc Ile31-Thr205
Human IL15RA-0270H Active Recombinant Human IL15RA protein, Fc-tagged HEK293 Fc Ile31-Thr205
Human IL15RA-128H Recombinant Human IL15RA Protein, Ile31-Thr205, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Ile31-Thr205
Human IL15RA-4677H Recombinant Human IL15RA Protein, Fc-tagged, PE-Labeled HEK293 Fc Ile 31 - Thr 205
Human IL15RA-1074H Recombinant Human IL15RA protein(Ile31-Thr205), His-tagged E.coli N-His Ile31-Thr205
Human IL15RA-4310H Recombinant Human IL15RA Protein (Met1-Thr205), C-Fc tagged Mammalian cells C-Fc Met1-Thr205
Mouse IL15RA-1553M Active Recombinant Mouse IL15RA, MIgG2a Fc-tagged CHO Fc
Mouse IL15RA-0268M Recombinant Mouse IL15RA protein(Met1-Lys205), hFc-tagged HEK293 C-hFc Met1-Lys205
Mouse Il15ra-5698M Recombinant Mouse Il15ra Protein (Gly33-Lys205), C-Fc tagged Mammalian cells C-Fc Gly33-Lys205
Mouse Il15ra-360M Active Recombinant Mouse Il15ra Protein, Fc-tagged Mouse myeloma cell line Fc
Mouse Il15ra-1662M Recombinant Mouse Il15ra Protein, His-tagged E.coli N-His Gly33-Ala263
Rat Il15ra-1663R Recombinant Rat Il15ra Protein, His&GST-tagged E.coli N-His&GST Ile10-Thr239
Rhesus Macaque IL15RA-2233R Recombinant Rhesus monkey IL15RA Protein, His-tagged Mammalian Cell His
Rhesus Macaque IL15RA-2054R Recombinant Rhesus Macaque IL15RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IL15RA-2054R-B Recombinant Rhesus Macaque IL15RA Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IL15RA involved in several pathways and played different roles in them. We selected most pathways IL15RA participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL15RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionCCL21B;IL1R2;CX3CR1;IFNA5;GM-CSF;BMP7B;TNFSF15;OSTN;CCL8
Jak-STAT signaling pathwayFHL1;PIAS2;NT5C3;IFNG1-2;IL12B;AKT2L;IL28RA;SOCS6;LEPR
Intestinal iIcosl;BLA;BLB1;CCL27B;PIGR;CXCL12B;BLB2;CD86;MAP3K14
ne network for IgA productionIL5;Il2;IL-15RA;IL15RA;CCL25;CXCR4B;H2-AB1;CXCR4;CD28
HTLV-I infectionCDC27;RRAS2;CCND3;FZD8;NFKB1;HLA-DQB1;AKT1;ITGAL;PPP3CB

IL15RA has several biochemical functions, for example, cytokine receptor activity, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL15RA itself. We selected most functions IL15RA had, and list some proteins which have the same functions with IL15RA. You can find most of the proteins on our site.

Function Related Protein
cytokine receptor activityIL4R.1;IL31RA;IL13RA2;CRFB6;LEPR;IL12B;IL2RGA;GHRA;FLT3
protein bindingDYNC1I1;CUL5;LAMP2;CXCL10;RAP1A;TOR1AIP1;ZUFSP;PDK1;ARF6
signal transducer activityPTK2B;OLFR488;VMN1R41;PTGER1A;VOPP1;OLFR998;GNG10;OMPB;OPN4XB

IL15RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL15RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL15RA.

IL15; IL2RB; IL2RG; CASK; BCL10; CDK4; CDK2; RCVRN; PIAS4

Gene Family

IL

Research Area

Related articles

Dalakas, MC; et al. Pathogenesis of immune-mediated neuropathies. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:658-666(2015).
Choi, J; Nam, SK; et al. Correlation between microsatellite instability-high phenotype and occult lymph node metastasis in gastric carcinoma. APMIS 123:215-222(2015).
  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
10/29/2020

    Effective in T-cell assays.

    03/10/2018

      High purity levels.

      05/28/2017

        Consistent receptor binding.

        Q&As (10)

        Ask a question
        How does immunoprecipitation validate IL15RA's association with IL2RB? 10/23/2022

        Immunoprecipitation validates IL15RA's binding to IL2RB in cells.

        What are the applications of CRISPR/Cas9 in studying IL15RA knockout models? 07/08/2021

        CRISPR/Cas9 technology aids in generating IL15RA knockout models.

        Could you explain the approaches to investigate IL15RA's role in autoimmune diseases? 03/15/2021

        Approaches unravel IL15RA's implication in autoimmune disease mechanisms.

        What experimental strategies differentiate IL15RA's role in innate and adaptive immunity? 06/17/2020

        Methods discern IL15RA's distinct roles in innate and adaptive immunity.

        What techniques characterize IL15RA isoform expression in tissues? 06/14/2020

        RT-PCR and Western blotting assess IL15RA isoform expression patterns.

        How is IL15RA's binding affinity to IL15 measured in vitro? 01/05/2019

        Binding affinity of IL15RA to IL15 quantified through surface plasmon resonance.

        What methods explore IL15RA's involvement in immune cell proliferation? 11/12/2017

        Proliferation assays investigate IL15RA's contribution to immune cell growth.

        How is IL15RA's interaction with JAK/STAT pathways analyzed? 11/11/2017

        IL15RA's interaction with JAK/STAT pathways probed using immunoblotting.

        How do siRNA knockdown experiments reveal IL15RA's role in signaling? 04/20/2017

        siRNA knockdown studies unveil IL15RA's impact on downstream signaling.

        Can you detail the use of FRET assays to study IL15RA dimerization? 01/09/2017

        FRET assays employed to elucidate IL15RA dimerization kinetics.

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