IL15RA
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Official Full Name
interleukin 15 receptor, alpha chain -
Overview
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and -
Synonyms
IL15RA;interleukin 15 receptor, alpha chain;interleukin-15 receptor subunit alpha;CD215;I15RA_HUMAN;IL 15R alpha;IL-15 receptor subunit alpha;IL-15R-alpha;IL-15RA;Interleukin 15 receptor alpha;Interleukin 15 receptor subunit alpha;MGC104179;sIL-15 receptor subunit alpha;sIL-15R-alpha;sIL-15RA;Soluble interleukin 15 receptor subunit alpha;Soluble interleukin-15 receptor subunit alpha;OTTMUSP00000011997;OTTMUSP00000011998;OTTMUSP00000011999;OTTMUSP00000051896;OTTMUSP00000051897;OTTMUSP00000051898;OTTMUSP00000051899;OTTMUSP00000051901;OTTMUSP00000051907;IL-15 receptor subunit al;AA690181
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- CHO
- Insect Cells
- HEK293
- Sf21 Cells
- Mammalian Cells
- Wheat Germ
- Human Cells
- Mouse myeloma cell
- HEK293T
- His
- Fc
- Avi
- Non
- GST
- Myc
Involved Pathway
IL15RA involved in several pathways and played different roles in them. We selected most pathways IL15RA participated on our site, such as Cytokine-cytokine receptor interaction,Jak-STAT signaling pathway,Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL15RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HTLV-I infection | AKT1,ATF1,LTBR,CRTC2,PRKACG,RRAS,PDGFRA,POLD1,IL1R2,WNT8A |
| Jak-STAT signaling pathway | IL9,CCND1,IL5,Gh,IFNK,SOCS7,STAT3,PRLRA,LEPB,IL17D |
| Intestinal i | MAP3K14,HLA-DRB3,IL6,TGFB1,CCL25,HLA-DOB,CD80,CCR9A,IL5,CXCL12 |
| ne network for IgA production | HLA-DRB1,MHC2DEB,HLA-DQA1,HLA-DPB1,IL-15RA,CCL27B,MAP3K14,ICOSLG,IL4,CXCL12B |
| Cytokine-cytokine receptor interaction | BMPR1AB,EDA,IL12BA,MPL,EPO,TNFSF11,ACVR1B,IFNA12,NT5C3,GM2002 |
Protein Function
IL15RA has several biochemical functions, for example, cytokine receptor activity,protein binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL15RA itself. We selected most functions IL15RA had, and list some proteins which have the same functions with IL15RA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZKSCAN5,ARHGAP33,SYT2,CXXC11,ZNF580,GIMAP7,ZBED4,TMEM203,NCOR1,CTLA4 |
| cytokine receptor activity | Il4ra,IL12B,CRFB17,IL4R.1,CRFB16,IL17RB,IL20RB,GHR,CRFB4,IL12RB1 |
| signal transducer activity | RGS6,PLK2,TMTOPS3B,GNAI2,TRAF3,RERG,TRIM63,TMTOPS3A,GPR27,TAAR14L |
Interacting Protein
IL15RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL15RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL15RA.
IL15;IL2RB;IL2RG;CASK;BCL10;CDK4;CDK2;RCVRN;PIAS4
Resources
Research Area
Cytokine and Growth Factor Receptors on VSMCNatural Killer Cells (NK Cells) Markers
Negative Regulators of the Jak/STAT Pathway
Receptors in the Jak/STAT Pathway
Natural Killer T (NKT) Cells
Common gamma Chain Family Receptors
Related Services
Related Products
References
- Dalakas, MC; et al. Pathogenesis of immune-mediated neuropathies. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:658-666(2015).
- Choi, J; Nam, SK; et al. Correlation between microsatellite instability-high phenotype and occult lymph node metastasis in gastric carcinoma. APMIS 123:215-222(2015).
