Recombinant Human IL15RA protein, His-Avi-tagged, Biotinylated

Cat.No. : IL15RA-273HB
Product Overview : Biotinylated Recombinant Human IL15R alpha Protein is expressed from mammalian with a His and Avi tag at the C-terminal. It contains Asp 21 - Glu 335.
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Description : Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 21.3 kDa.Due to glycosylation, the protein migrates to 50- 70KDa based on Bis-Tris PAGE result.
Protein length : It contains Asp 21 - Glu 335.
Endotoxin : Less than 0.1EU per ug by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
SDS-PAGE:
Gene Name : IL15RA interleukin 15 receptor, alpha [ Homo sapiens ]
Official Symbol : IL15RA
Synonyms : IL-15 R alpha;CD215;IL15RA;IL-15RA;IL-15R-alpha1
Gene ID : 3601
mRNA Refseq : NM_001243539
Protein Refseq : NP_001230468
MIM : 601070
UniProt ID : Q13261

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does immunoprecipitation validate IL15RA's association with IL2RB? 10/23/2022

Immunoprecipitation validates IL15RA's binding to IL2RB in cells.

What are the applications of CRISPR/Cas9 in studying IL15RA knockout models? 07/08/2021

CRISPR/Cas9 technology aids in generating IL15RA knockout models.

Could you explain the approaches to investigate IL15RA's role in autoimmune diseases? 03/15/2021

Approaches unravel IL15RA's implication in autoimmune disease mechanisms.

What experimental strategies differentiate IL15RA's role in innate and adaptive immunity? 06/17/2020

Methods discern IL15RA's distinct roles in innate and adaptive immunity.

What techniques characterize IL15RA isoform expression in tissues? 06/14/2020

RT-PCR and Western blotting assess IL15RA isoform expression patterns.

How is IL15RA's binding affinity to IL15 measured in vitro? 01/05/2019

Binding affinity of IL15RA to IL15 quantified through surface plasmon resonance.

What methods explore IL15RA's involvement in immune cell proliferation? 11/12/2017

Proliferation assays investigate IL15RA's contribution to immune cell growth.

How is IL15RA's interaction with JAK/STAT pathways analyzed? 11/11/2017

IL15RA's interaction with JAK/STAT pathways probed using immunoblotting.

How do siRNA knockdown experiments reveal IL15RA's role in signaling? 04/20/2017

siRNA knockdown studies unveil IL15RA's impact on downstream signaling.

Can you detail the use of FRET assays to study IL15RA dimerization? 01/09/2017

FRET assays employed to elucidate IL15RA dimerization kinetics.

Customer Reviews (3)

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Reviews
10/29/2020

    Effective in T-cell assays.

    03/10/2018

      High purity levels.

      05/28/2017

        Consistent receptor binding.

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