IL20RA
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Official Full Name
interleukin 20 receptor, alpha
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Background
The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). -
Synonyms
IL20RA; interleukin 20 receptor, alpha; interleukin-20 receptor subunit alpha; IL 20R1; ZCYTOR7; CRF2-8; IL-20RA; IL-20R-alpha; interleukin-20 receptor I; IL-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor class-II member;
- Involved Pathway
- Protein Function
- Interacting Protein
- IL20RA Related Articles
- IL20RA Related Gene Family
- IL20RA Related Research Area
IL20RA involved in several pathways and played different roles in them. We selected most pathways IL20RA participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL20RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | LIFRA;CCR5;IL21R.1;TNFRSF8;PDGFRA;IL2RGB;IFNB;PDGFRB;TGFB2 |
| Jak-STAT signaling pathway | RAF1B;IL5RA;IL11RA;EPO;Ifnl2;IL12RB1;PIK3R2;LEPA;IFNA1 |
IL20RA has several biochemical functions, for example, cytokine receptor activity, interleukin-20 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL20RA itself. We selected most functions IL20RA had, and list some proteins which have the same functions with IL20RA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine receptor activity | IRX1;GHRA;CRFB17;LEPR;IL12RB1;IL12B;PRLRA;CRFB15;CSF3R |
| interleukin-20 binding | IL20RA;IL20RB;IL22RA1 |
IL20RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL20RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL20RA.
MLH1
- Q&As
- Reviews
Q&As (10)
Ask a questionIL20RA increases IL-17 and IL-22 production.
IL20RA expression correlates with disease severity in psoriasis.
IL20RA is implicated in autoimmune diseases like psoriasis.
IL20RA modulates skin inflammation by activating keratinocytes.
IL20RA expression is upregulated in melanoma.
IL20RA activates the JAK-STAT signaling pathway.
IL20RA interacts with IL-20 and IL-24 receptors.
IL20RA induces Th17 cell differentiation.
IL20RA promotes keratinocyte migration.
IL20RA undergoes phosphorylation.
Customer Reviews (3)
Write a reviewGood for signaling studies. -
High specificity. -
Effective in skin models. -
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