Recombinant Human IL20RA protein, His & GST-tagged
Cat.No. : | IL20RA-1325H |
Product Overview : | Recombinant Human IL20RA aa. (Met269~Trp545 (Accession# Q9UHF4) fused with N-terminal His & GST tag was produced in E. coli cells. |
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Description : | This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His&GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 61.1kDa |
Protein length : | Met269~Trp545 (Accession# Q9UHF4) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >90% |
Characteristic : | The isoelectric point is 4.1. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | IL20RA interleukin 20 receptor subunit alpha [ Homo sapiens (human) ] |
Official Symbol : | IL20RA |
Synonyms : | IL20RA; interleukin 20 receptor subunit alpha; CRF2-8; IL-20R1; IL-20RA; IL-20R-alpha; interleukin-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor family 2 member 8; interleukin 20 receptor alpha subunit; interleukin 20 receptor, alpha; interleukin-20 receptor I |
Gene ID : | 53832 |
mRNA Refseq : | NM_001278722.1 |
Protein Refseq : | NP_001265651.1 |
UniProt ID : | Q9UHF4 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewGood for signaling studies.
High specificity.
Effective in skin models.
Q&As (10)
Ask a questionIL20RA increases IL-17 and IL-22 production.
IL20RA expression correlates with disease severity in psoriasis.
IL20RA is implicated in autoimmune diseases like psoriasis.
IL20RA modulates skin inflammation by activating keratinocytes.
IL20RA expression is upregulated in melanoma.
IL20RA activates the JAK-STAT signaling pathway.
IL20RA interacts with IL-20 and IL-24 receptors.
IL20RA induces Th17 cell differentiation.
IL20RA promotes keratinocyte migration.
IL20RA undergoes phosphorylation.
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