Recombinant Human IL20RA, His tagged

Cat.No. : IL20RA-779H
Product Overview : Recombinant Human IL20RA extracellular domain (NP_055247.21) (Met 1-Lys 250), fused with a polyhistidine tag at the C-terminus, was produced in Human Cell.
Availability July 25, 2024
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Source : HEK293
Species : Human
Form : Lyophilized from sterile 50 mM Tris, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human IL20Rα consists of 232 amino acids and has a calculated molecular mass of 26.8 kDa. As a result of glycosylation, rhIL20Rα migrates as an approximately 40-45 kDa protein in SDS-PAGE under reducing conditions.
Protein Length : Met 1-Lys 250
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : IL20RA interleukin 20 receptor, alpha [ Homo sapiens ]
Official Symbol : IL20RA
Synonyms : IL20RA; interleukin 20 receptor, alpha; interleukin-20 receptor subunit alpha; IL 20R1; ZCYTOR7; CRF2-8; IL-20RA; IL-20R-alpha; interleukin-20 receptor I; IL-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor class-II member 8; cytokine receptor family 2 member 8; IL-20R1; FLJ40993;
Gene ID : 53832
mRNA Refseq : NM_014432
Protein Refseq : NP_055247
MIM : 605620
UniProt ID : Q9UHF4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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07/12/2021

    Good for signaling studies.

    10/13/2017

      High specificity.

      10/03/2016

        Effective in skin models.

        Q&As (10)

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        What is the impact of IL20RA on cytokine secretion? 09/15/2021

        IL20RA increases IL-17 and IL-22 production.

        Does IL20RA expression correlate with disease severity in psoriasis? 10/07/2020

        IL20RA expression correlates with disease severity in psoriasis.

        What is IL20RA's role in autoimmune diseases? 05/06/2019

        IL20RA is implicated in autoimmune diseases like psoriasis.

        How does IL20RA modulate skin inflammation? 08/09/2018

        IL20RA modulates skin inflammation by activating keratinocytes.

        How does IL20RA expression change in cancerous tissues? 06/29/2018

        IL20RA expression is upregulated in melanoma.

        How does IL20RA influence the JAK-STAT signaling pathway? 12/26/2017

        IL20RA activates the JAK-STAT signaling pathway.

        Does IL20RA interact with other interleukin receptors? 09/17/2017

        IL20RA interacts with IL-20 and IL-24 receptors.

        How does IL20RA affect T-cell differentiation? 01/22/2017

        IL20RA induces Th17 cell differentiation.

        Does IL20RA have a role in cell migration? 08/09/2016

        IL20RA promotes keratinocyte migration.

        What post-translational modifications occur on IL20RA? 01/16/2016

        IL20RA undergoes phosphorylation.

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