Recombinant Human IL20RA, His tagged

• Cat.No.: IL20RA-779H
• Product Overview: Recombinant Human IL20RA extracellular domain (NP_055247.21) (Met 1-Lys 250), fused with a polyhistidine tag at the C-terminus, was produced in Human Cell.

Specification

• Source: HEK293
• Species: Human
• Form: Lyophilized from sterile 50 mM Tris, pH 8.0.
  Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant human IL20Rα consists of 232 amino acids and has a calculated molecular mass of 26.8 kDa. As a result of glycosylation, rhIL20Rα migrates as an approximately 40-45 kDa protein in SDS-PAGE under reducing conditions.
• Protein length: Met 1-Lys 250
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: IL20RA interleukin 20 receptor, alpha [ Homo sapiens ]
• Official Symbol: IL20RA
• Synonyms: IL20RA; interleukin 20 receptor, alpha; interleukin-20 receptor subunit alpha; IL 20R1; ZCYTOR7; CRF2-8; IL-20RA; IL-20R-alpha; interleukin-20 receptor I; IL-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor class-II member 8; cytokine receptor family 2 member 8; IL-20R1; FLJ40993
• Gene ID: 53832
• mRNA Refseq: NM_014432
• Protein Refseq: NP_055247
• MIM: 605620
• UniProt ID: Q9UHF4

Reviews

07/12/2021

Good for signaling studies.

10/13/2017

High specificity.

10/03/2016

Effective in skin models.

Q&As

What is the impact of IL20RA on cytokine secretion?

IL20RA increases IL-17 and IL-22 production.

Does IL20RA expression correlate with disease severity in psoriasis?

IL20RA expression correlates with disease severity in psoriasis.

What is IL20RA's role in autoimmune diseases?

IL20RA is implicated in autoimmune diseases like psoriasis.

How does IL20RA modulate skin inflammation?

IL20RA modulates skin inflammation by activating keratinocytes.

How does IL20RA expression change in cancerous tissues?

IL20RA expression is upregulated in melanoma.

How does IL20RA influence the JAK-STAT signaling pathway?

IL20RA activates the JAK-STAT signaling pathway.

Does IL20RA interact with other interleukin receptors?

IL20RA interacts with IL-20 and IL-24 receptors.

How does IL20RA affect T-cell differentiation?

IL20RA induces Th17 cell differentiation.

Does IL20RA have a role in cell migration?

IL20RA promotes keratinocyte migration.

What post-translational modifications occur on IL20RA?

IL20RA undergoes phosphorylation.