Active Recombinant Human IL20RA protein, Fc-tagged
Cat.No. : | IL20RA-219H |
Product Overview : | Recombinant Human IL20RA protein(Val 30 - Lys 250), fused with Fc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Human IL-20, His Tag immobilized on CM5 Chip can bind Human IL-20 R alpha, Fc Tag with an affinity constant of 4.42 μM as determined in a SPR assay (Biacore 8K). |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminus.The protein has a calculated MW of 51.7 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Proteinlength : | Val30-Lys250 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Protein length : | Val30-Lys250 |
Gene Name : | IL20RA interleukin 20 receptor, alpha [ Homo sapiens ] |
Official Symbol : | IL20RA |
Synonyms : | IL20RA; interleukin 20 receptor, alpha; interleukin-20 receptor subunit alpha; IL 20R1; ZCYTOR7; CRF2-8; IL-20RA; IL-20R-alpha; interleukin-20 receptor I; IL-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor class-II member 8; cytokine receptor family 2 member 8; IL-20R1; FLJ40993; |
Gene ID : | 53832 |
mRNA Refseq : | NM_014432 |
Protein Refseq : | NP_055247 |
MIM : | 605620 |
UniProt ID : | Q9UHF4 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewGood for signaling studies.
High specificity.
Effective in skin models.
Q&As (10)
Ask a questionIL20RA increases IL-17 and IL-22 production.
IL20RA expression correlates with disease severity in psoriasis.
IL20RA is implicated in autoimmune diseases like psoriasis.
IL20RA modulates skin inflammation by activating keratinocytes.
IL20RA expression is upregulated in melanoma.
IL20RA activates the JAK-STAT signaling pathway.
IL20RA interacts with IL-20 and IL-24 receptors.
IL20RA induces Th17 cell differentiation.
IL20RA promotes keratinocyte migration.
IL20RA undergoes phosphorylation.
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