Recombinant Human IL20RA Protein, His-tagged
Cat.No. : | IL20RA-968H |
Product Overview : | Recombinant Human IL20RA(Val30-Lys250) fused with His tag at N-terminal was expressed in HEK293 cells. |
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Description : | This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 cells |
Tag : | His |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Molecular Mass : | 26.3 kDa |
Endotoxin : | < 0.1 EU per µg protein as determined by LAL test |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Resuspend the protein to the desired concentration in proper buffer. |
Protein length : | Val30-Lys250 |
Gene Name : | IL20RA interleukin 20 receptor, alpha [ Homo sapiens ] |
Official Symbol : | IL20RA |
Synonyms : | IL20RA; interleukin 20 receptor, alpha; interleukin-20 receptor subunit alpha; IL 20R1; ZCYTOR7; CRF2-8; IL-20RA; IL-20R-alpha; interleukin-20 receptor I; IL-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor class-II member 8; cytokine receptor family 2 member 8; IL-20R1; FLJ40993; |
Gene ID : | 53832 |
mRNA Refseq : | NM_014432 |
Protein Refseq : | NP_055247 |
MIM : | 605620 |
UniProt ID : | Q9UHF4 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewGood for signaling studies.
High specificity.
Effective in skin models.
Q&As (10)
Ask a questionIL20RA increases IL-17 and IL-22 production.
IL20RA expression correlates with disease severity in psoriasis.
IL20RA is implicated in autoimmune diseases like psoriasis.
IL20RA modulates skin inflammation by activating keratinocytes.
IL20RA expression is upregulated in melanoma.
IL20RA activates the JAK-STAT signaling pathway.
IL20RA interacts with IL-20 and IL-24 receptors.
IL20RA induces Th17 cell differentiation.
IL20RA promotes keratinocyte migration.
IL20RA undergoes phosphorylation.
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