Recombinant Mouse Il20ra protein, His-tagged

• Cat.No.: Il20ra-1326M
• Product Overview: Recombinant Mouse Il20ra aa. (Leu268~Trp538 (Accession # Q6PHB0) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 32.3kDa
• Protein length: Leu268~Trp538 (Accession # Q6PHB0)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 4.6.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: Il20ra interleukin 20 receptor, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Il20ra
• Synonyms: Il20ra; interleukin 20 receptor, alpha; E230031K19; interleukin-20 receptor subunit alpha; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20R1; IL-20RA
• Gene ID: 237313
• mRNA Refseq: NM_172786.2
• Protein Refseq: NP_766374.1
• UniProt ID: Q6PHB0

Reviews

07/12/2021

Good for signaling studies.

10/13/2017

High specificity.

10/03/2016

Effective in skin models.

Q&As

What is the impact of IL20RA on cytokine secretion?

IL20RA increases IL-17 and IL-22 production.

Does IL20RA expression correlate with disease severity in psoriasis?

IL20RA expression correlates with disease severity in psoriasis.

What is IL20RA's role in autoimmune diseases?

IL20RA is implicated in autoimmune diseases like psoriasis.

How does IL20RA modulate skin inflammation?

IL20RA modulates skin inflammation by activating keratinocytes.

How does IL20RA expression change in cancerous tissues?

IL20RA expression is upregulated in melanoma.

How does IL20RA influence the JAK-STAT signaling pathway?

IL20RA activates the JAK-STAT signaling pathway.

Does IL20RA interact with other interleukin receptors?

IL20RA interacts with IL-20 and IL-24 receptors.

How does IL20RA affect T-cell differentiation?

IL20RA induces Th17 cell differentiation.

Does IL20RA have a role in cell migration?

IL20RA promotes keratinocyte migration.

What post-translational modifications occur on IL20RA?

IL20RA undergoes phosphorylation.