Recombinant Human IL20RA Protein, Fc-tagged
Cat.No. : | IL20RA-969H |
Product Overview : | Recombinant Human IL20RA fused with Fc tag at C-terminal was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 cells |
Tag : | Fc |
Form : | Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4 |
Molecular Mass : | 26.3kD |
AA Sequence : | VPCVSGGLPKPANITFLSINMKNVL QWTPPEGLQGVKVTYTVQYFIYGQK KWLNKSECRNINRTYCDLSAETSDY EHQYYAKVKAIWGTKCSKWAESGRF YPFLETQIGPPEVALTTDEKSISVV LTAPEKWKRNPEDLPVSMQQIYSNL KYNVSVLNTKSNRTWSQCVTNHTLV LTWLEPNTLYCVHVESFVPGPPRRA QPSEKQCARTLKDQSSEFKAKVDHH HHHH |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | IL20RA interleukin 20 receptor, alpha [ Homo sapiens ] |
Official Symbol : | IL20RA |
Synonyms : | IL20RA; interleukin 20 receptor, alpha; interleukin-20 receptor subunit alpha; IL 20R1; ZCYTOR7; CRF2-8; IL-20RA; IL-20R-alpha; interleukin-20 receptor I; IL-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor class-II member 8; cytokine receptor family 2 member 8; IL-20R1; FLJ40993; |
Gene ID : | 53832 |
mRNA Refseq : | NM_014432 |
Protein Refseq : | NP_055247 |
MIM : | 605620 |
UniProt ID : | Q9UHF4 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionIL20RA increases IL-17 and IL-22 production.
IL20RA expression correlates with disease severity in psoriasis.
IL20RA is implicated in autoimmune diseases like psoriasis.
IL20RA modulates skin inflammation by activating keratinocytes.
IL20RA expression is upregulated in melanoma.
IL20RA activates the JAK-STAT signaling pathway.
IL20RA interacts with IL-20 and IL-24 receptors.
IL20RA induces Th17 cell differentiation.
IL20RA promotes keratinocyte migration.
IL20RA undergoes phosphorylation.
Customer Reviews (3)
Write a reviewGood for signaling studies.
High specificity.
Effective in skin models.
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