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Recombinant Human IL20RA Protein, Fc-tagged

Cat.No. : IL20RA-969H
Product Overview : Recombinant Human IL20RA fused with Fc tag at C-terminal was expressed in HEK293 cells.
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  • Gene Information
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Description : This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants.
Source : HEK293 cells
Tag : Fc
Form : Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4
Molecular Mass : 26.3kD
AA Sequence : VPCVSGGLPKPANITFLSINMKNVL QWTPPEGLQGVKVTYTVQYFIYGQK KWLNKSECRNINRTYCDLSAETSDY EHQYYAKVKAIWGTKCSKWAESGRF YPFLETQIGPPEVALTTDEKSISVV LTAPEKWKRNPEDLPVSMQQIYSNL KYNVSVLNTKSNRTWSQCVTNHTLV LTWLEPNTLYCVHVESFVPGPPRRA QPSEKQCARTLKDQSSEFKAKVDHH HHHH
Endotoxin : Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Gene Name : IL20RA interleukin 20 receptor, alpha [ Homo sapiens ]
Official Symbol : IL20RA
Synonyms : IL20RA; interleukin 20 receptor, alpha; interleukin-20 receptor subunit alpha; IL 20R1; ZCYTOR7; CRF2-8; IL-20RA; IL-20R-alpha; interleukin-20 receptor I; IL-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor class-II member 8; cytokine receptor family 2 member 8; IL-20R1; FLJ40993;
Gene ID : 53832
mRNA Refseq : NM_014432
Protein Refseq : NP_055247
MIM : 605620
UniProt ID : Q9UHF4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What is the impact of IL20RA on cytokine secretion? 09/15/2021

IL20RA increases IL-17 and IL-22 production.

Does IL20RA expression correlate with disease severity in psoriasis? 10/07/2020

IL20RA expression correlates with disease severity in psoriasis.

What is IL20RA's role in autoimmune diseases? 05/06/2019

IL20RA is implicated in autoimmune diseases like psoriasis.

How does IL20RA modulate skin inflammation? 08/09/2018

IL20RA modulates skin inflammation by activating keratinocytes.

How does IL20RA expression change in cancerous tissues? 06/29/2018

IL20RA expression is upregulated in melanoma.

How does IL20RA influence the JAK-STAT signaling pathway? 12/26/2017

IL20RA activates the JAK-STAT signaling pathway.

Does IL20RA interact with other interleukin receptors? 09/17/2017

IL20RA interacts with IL-20 and IL-24 receptors.

How does IL20RA affect T-cell differentiation? 01/22/2017

IL20RA induces Th17 cell differentiation.

Does IL20RA have a role in cell migration? 08/09/2016

IL20RA promotes keratinocyte migration.

What post-translational modifications occur on IL20RA? 01/16/2016

IL20RA undergoes phosphorylation.

Customer Reviews (3)

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Reviews
07/12/2021

    Good for signaling studies.

    10/13/2017

      High specificity.

      10/03/2016

        Effective in skin models.

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