il29

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il29

Official Full Name interleukin 29 (interferon, lambda 1)
Background This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Synonyms IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29
    • Species :
    • Human
    • Source :
    • CHO
    • E.coli
    • HEK293
    • NSO
    • Tag :
    • Fc
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL29-001H Recombinant Human IL29, MIgG2a Fc-tagged CHO Fc
    Human IL29-002H Recombinant Human IL29, HIgG1 Fc-tagged, mutant CHO Fc
    Human IL29-003H Recombinant Human IL29, HIgG1 Fc-tagged CHO Fc
    Human IL29-100H Recombinant Human IL29 protein E.coli N/A
    Human IL29-14194H Recombinant Human IL29, His-tagged E.coli His
    Human IL29-222H Recombinant Human Interleukin 29 (Interferon, Lambda 1), His-tagged NSO His
    Human IL29-37H Interleukin-29 (Interferon Lamda 1) Reference standard N/A
    Human IL29-381H Recombinant Human IL29 protein, His-tagged HEK293 His
    Human IL29-5200H Recombinant Human IL29 Protein E.coli N/A
    Human IL29-5228HCL Recombinant Human IL29 293 Cell Lysate HEK293 N/A
    Human IL29-602H Recombinant Human Interleukin 29 (interferon, lambda 1) HEK293 N/A

    il29 involved in several pathways and played different roles in them. We selected most pathways il29 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with il29 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL1B; VEGFAB; CXCL6; IL1R2; GM13305; CXCL8B.3; CXCR1; IFNB1; IL2RGB; TNFRSF6B
    Jak-STAT signaling pathway TYK2; RAF1; PTPN2A; CISH; AKT2; STAT5A; IL19; STAM; IL2RB; PIAS4B

    il29 has several biochemical functions, for example, cytokine activity, interleukin-28 receptor binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by il29 itself. We selected most functions il29 had, and list some proteins which have the same functions with il29. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity CCL20A.3; WNT5A; GDF10B; IL12BA; IL36RN; ADIPOQ; CLCF1; MIF; IL29; CCL38A.5
    interleukin-28 receptor binding IL29
    receptor binding ACOT8; LAMA2; Fert2; PECR; AGRP2; PEX14; CNPY3; MLN; CADM4; Ar

    il29 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with il29 here. Most of them are supplied by our site. Hope this information will be useful for your research of il29.

    Ghoneum, M; Agrawal, S; et al. MGN-3/BIOBRAN ENHANCES GENERATION OF CYTOTOXIC CD8+T CELLS VIA UPREGULATION OF DEC-205 EXPRESSION ON DENDRITIC CELLS. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY 27:523-530(2014).
    Zhang, LL; Jilg, N; et al. IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway. JOURNAL OF HEPATOLOGY 55:289-298(2011).
    WILLIAMS, RC; MALONE, CC; et al. IGG ANTI-F(AB')(2) ANTIBODIES FROM SLE PATIENTS REACT WITH IMMUNODOMINANT RESIDUES IN KAPPA-CDRS, BUT SHOW REDUCED C-KAPPA REGION REACTIVITY. CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY 77:366-373(1995).

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