IL36A
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Official Full Name
interleukin 36, alpha
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Background
IL1F6 is a member of the interleukin 1 cytokine family. It has a conserved 12-stranded beta-trefoil structure. Binding analysis failed to detect interaction with multiple IL1R family members. IL-1F6 is a secreted cytokine that expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. -
Synonyms
IL36A; interleukin 36, alpha; IL1F6, interleukin 1 family, member 6 (epsilon); interleukin-36 alpha; FIL1; FIL1E; IL 1F6; IL1(EPSILON); MGC129552; MGC129553; FIL1(EPSILON); IL 1H1; IL1RP2; MGC151479; MGC151481; OTTMUSP00000012798; FIL1 epsilon; IL 1 epsilon; IL-1 epsilon; IL-1F6; IL1E; IL1F6; IL1F6_HUMAN; Interleukin 1 epsilon; Interleukin 1 family member 6 (epsilon); Interleukin 1 family member 6; Interleukin 36 alpha; Interleukin-1 epsilon; Interleukin-1 family member 6; RP23-176J12.4; OTTHUMP00000203688; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin 1 family, member 6 (epsilon);
- Involved Pathway
- Protein Function
- Interacting Protein
- IL36A Related Articles
- IL36A Related Gene Family
- IL36A Related Research Area
IL36A involved in several pathways and played different roles in them. We selected most pathways IL36A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL36A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
IL36A has several biochemical functions, for example, cytokine activity, interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL36A itself. We selected most functions IL36A had, and list some proteins which have the same functions with IL36A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | IL16;IL17A/F3;LFT1;IL7;FLT3LG;CTF1;CSF3;CXCL9;CMTM2 |
| interleukin-1 receptor binding | TRIP6;IL36B;IL1RN;IL37;TLR9;IL36RN;IL36G;IL1F10;IL36A |
IL36A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL36A here. Most of them are supplied by our site. Hope this information will be useful for your research of IL36A.
- Q&As
- Reviews
Q&As (6)
Ask a questionIn general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.
The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.
IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.
IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.
The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.
Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.
Customer Reviews (3)
Write a reviewWestern blot can simultaneously detect the purity and specificity of IL-36A. -
The purity of IL-36A can be preliminarily detected by SDS-PAGE electrophoresis and verified and quantified according to molecular weight. -
Infrared spectroscopy can be used to detect the structural characteristics of IL-36A, such as the main structure of the protein and the interaction of amino acid residues. -
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