• Official Full Name

    interleukin 36, alpha

  • Background

    IL1F6 is a member of the interleukin 1 cytokine family. It has a conserved 12-stranded beta-trefoil structure. Binding analysis failed to detect interaction with multiple IL1R family members. IL-1F6 is a secreted cytokine that expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines.
  • Synonyms

    IL36A; interleukin 36, alpha; IL1F6, interleukin 1 family, member 6 (epsilon); interleukin-36 alpha; FIL1; FIL1E; IL 1F6; IL1(EPSILON); MGC129552; MGC129553; FIL1(EPSILON); IL 1H1; IL1RP2; MGC151479; MGC151481; OTTMUSP00000012798; FIL1 epsilon; IL 1 epsilon; IL-1 epsilon; IL-1F6; IL1E; IL1F6; IL1F6_HUMAN; Interleukin 1 epsilon; Interleukin 1 family member 6 (epsilon); Interleukin 1 family member 6; Interleukin 36 alpha; Interleukin-1 epsilon; Interleukin-1 family member 6; RP23-176J12.4; OTTHUMP00000203688; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin 1 family, member 6 (epsilon);
    • Type:
    • Recombinant Proteins
    • GMP Proteins
    • Cell & Tissue Lysates
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Human Cells
    • Tag :
    • GST
    • His
    • His(C
    • ter)
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL36A-139H Recombinant Human IL36A protein E.coli N/A
    Human IL36A-151H Recombinant Human IL36A Protein, His-tagged Human Cells His
    Human IL36A-507H Recombinant Human IL36A protein E.coli N/A
    Human IL1F6-317H Recombinant Human IL1F6 E.coli N/A
    Human IL36A-4338HG GMP Recombinant Human IL36A protein E.coli N/A
    Human IL36A-4912H Recombinant Human IL36A protein, GST-tagged E.coli GST
    Human IL1F6-158H Recombinant Human Interleukin 1 Family, Member 6, His-tagged E.coli His
    Human IL36A-506H Recombinant Human IL36A protein E.coli N/A
    Human IL36A-2578H Recombinant Human IL36A protein, His-tagged E.coli His
    Human IL36A-195H Recombinant Active Human IL36A Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human IL36A-7293H Recombinant Human IL36A, His tagged E.coli His
    Human IL36A-5238HCL Recombinant Human IL1F6 293 Cell Lysate HEK293 N/A
    Human IL1F6-398H Active Recombinant Human Interleukin 1 Family, Member 6 (Epsilon) Human N/A
    Human IL36A-3232H Recombinant Human IL36A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Il1f6-550M Recombinant Mouse Il1f6 protein E.coli N/A
    Mouse Il1f6-551M Recombinant Mouse Il1f6 protein E.coli N/A
    Mouse Il1f6-552M Active Recombinant Mouse Il1f6 E.coli N/A
    Mouse Il36a-3506M Recombinant Mouse Il36a Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Il1f6-382M Recombinant Mouse Il1f6, None tagged E.coli N/A
    Mouse Il36a-196M Recombinant Active Mouse IL36A Protein, His-tagged(C-ter) E.coli His(C-ter)
    Mouse Il1f6-49M Recombinant Mouse Il36a protein, His-tagged E.coli His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL36A Related Articles
    • IL36A Related Gene Family
    • IL36A Related Research Area

    IL36A involved in several pathways and played different roles in them. We selected most pathways IL36A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL36A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    IL36A has several biochemical functions, for example, cytokine activity, interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL36A itself. We selected most functions IL36A had, and list some proteins which have the same functions with IL36A. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activityIL16;IL17A/F3;LFT1;IL7;FLT3LG;CTF1;CSF3;CXCL9;CMTM2
    interleukin-1 receptor bindingTRIP6;IL36B;IL1RN;IL37;TLR9;IL36RN;IL36G;IL1F10;IL36A

    IL36A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL36A here. Most of them are supplied by our site. Hope this information will be useful for your research of IL36A.

    Chen, DY; Chen, YM; et al. Th17-Related Cytokines in Systemic Lupus Erythematosus Patients with Dilated Cardiomyopathies: A Possible Linkage to Parvovirus B19 Infection. PLOS ONE 9:-(2014).
    Castro, M; Wenzel, SE; et al. Benralizumab, an anti-interleukin 5 receptor alpha monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study. LANCET RESPIRATORY MEDICINE 2:879-890(2014).
    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    Does IL36A carry a fever risk? 04/27/2022

    In general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.

    How to prepare IL36A? 09/07/2021

    The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.

    In what inflammatory diseases does recombinant IL36A have potential applications? 05/24/2021

    IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.

    Does IL36A have anti-tumor effects? 08/22/2020

    IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.

    How is the research progress of IL36A? 06/05/2020

    The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.

    Can IL36A be used in animal experiments? 02/13/2019

    Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.

    Customer Reviews (3)

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      Western blot can simultaneously detect the purity and specificity of IL-36A. -


        The purity of IL-36A can be preliminarily detected by SDS-PAGE electrophoresis and verified and quantified according to molecular weight. -


          Infrared spectroscopy can be used to detect the structural characteristics of IL-36A, such as the main structure of the protein and the interaction of amino acid residues. -

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