• Official Full Name

    interleukin 36, alpha

  • Overview

    IL1F6 is a member of the interleukin 1 cytokine family. It has a conserved 12-stranded beta-trefoil structure. Binding analysis failed to detect interaction with multiple IL1R family members. IL-1F6 is a secreted cytokine that expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines.
  • Synonyms

    IL36A; interleukin 36, alpha; IL1F6, interleukin 1 family, member 6 (epsilon); interleukin-36 alpha; FIL1; FIL1E; IL 1F6; IL1(EPSILON); MGC129552; MGC129553; FIL1(EPSILON); IL 1H1; IL1RP2; MGC151479; MGC151481; OTTMUSP00000012798; FIL1 epsilon; IL 1 epsilon; IL-1 epsilon; IL-1F6; IL1E; IL1F6; IL1F6_HUMAN; Interleukin 1 epsilon; Interleukin 1 family member 6 (epsilon); Interleukin 1 family member 6; Interleukin 36 alpha; Interleukin-1 epsilon; Interleukin-1 family member 6; RP23-176J12.4; OTTHUMP00000203688; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin 1 family, member 6 (epsilon);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Human Cells
  • C
  • His
  • GST
  • His(C
  • ter)
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL36A-507H Active Recombinant Human IL36A protein(Ala6-Phe158) E.coli N/A Ala6-Phe158
Human IL1F6-398H Active Recombinant Human Interleukin 1 Family, Member 6 (Epsilon) Human N/A
Human IL36A-139H Recombinant Human IL36A protein E.coli N/A
Human IL1F6-317H Recombinant Human IL1F6 E.coli N/A
Human IL1F6-158H Recombinant Human Interleukin 1 Family, Member 6, His-tagged E.coli His
Human IL36A-506H Recombinant Human IL36A protein E.coli N/A 158
Human IL36A-7293H Recombinant Human IL36A protein, His-tagged E.coli His Lys6-Phe158
Human IL36A-5238HCL Recombinant Human IL1F6 293 Cell Lysate HEK293 N/A
Human IL36A-4338HG Active GMP Recombinant Human IL36A protein E.coli N/A
Human IL36A-125H Active Recombinant Human IL36A Protein (Lys6-Phe158), C-His tagged, Animal-free, Carrier-free E.coli C-His Lys6-Phe158
Human IL36A-3515H Recombinant Human IL36A Protein (Met1-Phe158), His tagged E.coli His Met1-Phe158
Human IL36A-3232H Recombinant Human IL36A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL36A-2578H Recombinant Human IL36A protein, His-tagged E.coli His Met1-Phe158
Human IL36A-151H Recombinant Human IL36A Protein, His-tagged Human Cells His
Human IL36A-4912H Recombinant Human IL36A protein, GST-tagged E.coli GST 1-158aa
Human IL36A-195H Recombinant Active Human IL36A Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse Il1f6-552M Active Recombinant Mouse Il1f6 E.coli N/A
Mouse Il1f6-551M Recombinant Mouse Il1f6 protein E.coli N/A 153
Mouse Il1f6-49M Recombinant Mouse Il36a protein, His-tagged E.coli His
Mouse Il1f6-550M Recombinant Mouse Il1f6 protein E.coli N/A 160
Mouse Il36a-196M Recombinant Active Mouse IL36A Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse Il36a-249M Active Recombinant Mouse Il36a Protein (Met1-His160), C-His tagged, Animal-free, Carrier-free E.coli C-His Met1-His160
Mouse Il36a-3506M Recombinant Mouse Il36a Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IL36A involved in several pathways and played different roles in them. We selected most pathways IL36A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL36A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

IL36A has several biochemical functions, for example, cytokine activity, interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL36A itself. We selected most functions IL36A had, and list some proteins which have the same functions with IL36A. You can find most of the proteins on our site.

Function Related Protein
cytokine activityIL25;BMP15;MSTNA;BMP5;AREG;GM13287;CSF1;NDP;IFNK
interleukin-1 receptor bindingIL36G;IL36A;IL36B;IL1RN;IL1RAP;IL1F10;IL1B;Il1f6;IL36RN

IL36A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL36A here. Most of them are supplied by our site. Hope this information will be useful for your research of IL36A.

Gene Family


Research Area

Related articles

Chen, DY; Chen, YM; et al. Th17-Related Cytokines in Systemic Lupus Erythematosus Patients with Dilated Cardiomyopathies: A Possible Linkage to Parvovirus B19 Infection. PLOS ONE 9:-(2014).
Castro, M; Wenzel, SE; et al. Benralizumab, an anti-interleukin 5 receptor alpha monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study. LANCET RESPIRATORY MEDICINE 2:879-890(2014).
  • Reviews
  • Q&As

Customer Reviews (3)

Write a review

    When conducting experiments with HSP90AA1, clear and reliable interpretation of results can be obtained.


      The IL36A product has low endotoxin levels and does not interfere with experimental results.


        IL36A has important application value in the field of drug research and development, and has achieved certain research results.

        Q&As (6)

        Ask a question
        Does IL36A carry a fever risk? 04/27/2022

        In general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.

        How to prepare IL36A? 09/07/2021

        The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.

        In what inflammatory diseases does recombinant IL36A have potential applications? 05/24/2021

        IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.

        Does IL36A have anti-tumor effects? 08/22/2020

        IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.

        How is the research progress of IL36A? 06/05/2020

        The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.

        Can IL36A be used in animal experiments? 02/13/2019

        Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.

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