Recombinant Human IL36A Protein, His-tagged
Cat.No. : | IL36A-151H |
Product Overview : | Recombinant Human interleukin 36 alpha(IL36A)(NM_014440) protein, with a His tag, was expressed in human cells. |
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Description : | The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.16, without any preservatives. |
Molecular Mass : | 17.5 kDa |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name : | IL36A interleukin 36, alpha [ Homo sapiens ] |
Official Symbol : | IL36A |
Synonyms : | IL36A; interleukin 36, alpha; IL1F6, interleukin 1 family, member 6 (epsilon); interleukin-36 alpha; FIL1; FIL1E; IL 1F6; IL1(EPSILON); MGC129552; MGC129553; FIL1 epsilon; IL-1 epsilon; interleukin-1 epsilon; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin-1 family member 6; interleukin 1 family, member 6 (epsilon); IL1F6; IL-1F6; FIL1(EPSILON); |
Gene ID : | 27179 |
mRNA Refseq : | NM_014440 |
Protein Refseq : | NP_055255 |
MIM : | 605509 |
UniProt ID : | Q9UHA7 |
Products Types
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IL36A-195H | Recombinant Active Human IL36A Protein, His-tagged(C-ter) | +Inquiry |
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Il36a-3506M | Recombinant Mouse Il36a Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
IL36A-5238HCL | Recombinant Human IL1F6 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewWhen conducting experiments with HSP90AA1, clear and reliable interpretation of results can be obtained.
The IL36A product has low endotoxin levels and does not interfere with experimental results.
IL36A has important application value in the field of drug research and development, and has achieved certain research results.
Q&As (6)
Ask a questionIn general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.
The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.
IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.
IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.
The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.
Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.
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