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Recombinant Human IL36A Protein, His-tagged

Cat.No. : IL36A-151H
Product Overview : Recombinant Human interleukin 36 alpha(IL36A)(NM_014440) protein, with a His tag, was expressed in human cells.
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Description : The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
Source : Human Cells
Species : Human
Tag : His
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.16, without any preservatives.
Molecular Mass : 17.5 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : IL36A interleukin 36, alpha [ Homo sapiens ]
Official Symbol : IL36A
Synonyms : IL36A; interleukin 36, alpha; IL1F6, interleukin 1 family, member 6 (epsilon); interleukin-36 alpha; FIL1; FIL1E; IL 1F6; IL1(EPSILON); MGC129552; MGC129553; FIL1 epsilon; IL-1 epsilon; interleukin-1 epsilon; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin-1 family member 6; interleukin 1 family, member 6 (epsilon); IL1F6; IL-1F6; FIL1(EPSILON);
Gene ID : 27179
mRNA Refseq : NM_014440
Protein Refseq : NP_055255
MIM : 605509
UniProt ID : Q9UHA7

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
07/20/2022

    When conducting experiments with HSP90AA1, clear and reliable interpretation of results can be obtained.

    03/12/2021

      The IL36A product has low endotoxin levels and does not interfere with experimental results.

      08/12/2020

        IL36A has important application value in the field of drug research and development, and has achieved certain research results.

        Q&As (6)

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        Does IL36A carry a fever risk? 04/27/2022

        In general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.

        How to prepare IL36A? 09/07/2021

        The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.

        In what inflammatory diseases does recombinant IL36A have potential applications? 05/24/2021

        IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.

        Does IL36A have anti-tumor effects? 08/22/2020

        IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.

        How is the research progress of IL36A? 06/05/2020

        The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.

        Can IL36A be used in animal experiments? 02/13/2019

        Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.

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