Cat.No.:	IL36A-139H
Product Overview:	Recombinant Human IL36A was expressed in E. coli.
Description:	IL-1 epsilon is an actively secreted member of the IL-1 family of cytokines. It is mainly expressed in tissues with epithelial cells and in psoriatic plaques, as well as by monocytes, B cells and T cells. IL-1 epsilon has been shown to signal through the IL-Rrp2 receptor which is primarily expressed on certain denditic cells, and to act as an agonist of NF-kappaB which then stimulates the inflammatory response in bronchial epithelial cells.
Source:	E. coli
Species:	Human
Form:	Lyophilized from a 0.2 μm filtered solution in PBS, NaCl and Tween® 20 with BSA as a carrier protein
Molecular Mass:	17.4 kDa
Endotoxin:	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity:	>95%
Applications:	Cell Assay
Storage:	The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade - 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Reconstitution:	Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

Gene Name:	IL36A interleukin 36, alpha [ Homo sapiens ]
Official Symbol:	IL36A
Synonyms:	IL36A; interleukin 36, alpha; IL1F6, interleukin 1 family, member 6 (epsilon); interleukin-36 alpha; FIL1; FIL1E; IL 1F6; IL1(EPSILON); MGC129552; MGC129553; FIL1 epsilon; IL-1 epsilon; interleukin-1 epsilon; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin-1 family member 6; interleukin 1 family, member 6 (epsilon); IL1F6; IL-1F6; FIL1(EPSILON);
Gene ID:	27179
mRNA Refseq:	NM_014440
Protein Refseq:	NP_055255
MIM:	605509
UniProt ID:	Q9UHA7
Chromosome Location:	2q12-q14.1
Function:	cytokine activity; interleukin-1 receptor binding;

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