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Active Recombinant Human IL36A protein(Ala6-Phe158)

Cat.No. : IL36A-507H
Product Overview : Recombinant Human IL1F6 (Q9UHA7) (Ala6-Phe158) was expressed and purified in E. coli, with two additional amino acids (Gly & Pro) at the N-terminus.
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Source : E. coli
Species : Human
Tag : Non
Protein length : Ala6-Phe158
Form : Lyophilized from sterile PBS pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by its ability to induce IL8 secretion in A431 human epithelial carcinoma cells. The ED50 for this effect is typically 5-20 ng/mL.
Molecular Mass : The recombinant human IL1F6 consists of 155 amino acids and predicts a molecular mass of 17 .2 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions.
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL36A interleukin 36, alpha [ Homo sapiens ]
Official Symbol : IL36A
Synonyms : IL36A; interleukin 36, alpha; IL1F6, interleukin 1 family, member 6 (epsilon); interleukin-36 alpha; FIL1; FIL1E; IL 1F6; IL1(EPSILON); MGC129552; MGC129553; FIL1 epsilon; IL-1 epsilon; interleukin-1 epsilon; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin-1 family member 6; interleukin 1 family, member 6 (epsilon); IL1F6; IL-1F6; FIL1(EPSILON);
Gene ID : 27179
mRNA Refseq : NM_014440
Protein Refseq : NP_055255
MIM : 605509
UniProt ID : Q9UHA7

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
07/20/2022

    When conducting experiments with HSP90AA1, clear and reliable interpretation of results can be obtained.

    03/12/2021

      The IL36A product has low endotoxin levels and does not interfere with experimental results.

      08/12/2020

        IL36A has important application value in the field of drug research and development, and has achieved certain research results.

        Q&As (6)

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        Does IL36A carry a fever risk? 04/27/2022

        In general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.

        How to prepare IL36A? 09/07/2021

        The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.

        In what inflammatory diseases does recombinant IL36A have potential applications? 05/24/2021

        IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.

        Does IL36A have anti-tumor effects? 08/22/2020

        IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.

        How is the research progress of IL36A? 06/05/2020

        The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.

        Can IL36A be used in animal experiments? 02/13/2019

        Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.

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