Recombinant Human IL1F6
Cat.No. : | IL1F6-317H |
Product Overview : | Recombinant Human IL-1F6 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 158 amino acids and having a molecular mass of 17.7 kDa. |
- Specification
- Gene Information
- Related Products
- Download
Cat. No. : | IL1F6-317H |
Description : | Human interleukin family 1, member 6 (hIL-1F6 / FIL1-epsilon) is a member of the interleukin 1 cytokine family. IL-1F6 is expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines.IL-1F6 is the only IL-1 family member found to be expressed on T-cells. IL-1F6 is reported to function via receptor complex of IL-1Rrp2 and IL-1RAcP. Recombinant IL-1F6, along with IL-1F8 and IL-1F9, has been shown to act as an agonist by activating the pathway involving NFκB and MAPK in an IL-1Rrp2 dependent manner. |
Biological Activity : | As measured by its binding ability in a functional ELISA, immobilized rHuIL-1F6 at 1 μg/ml (100 μl/well) can bind rHuIL-1 Rrp2/Fc Chimera with a linear range of 0.15~5 μg/ml. |
Purity : | Greater than 95% as determined by (a) Analysis by RP-HPLC; (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. |
Amino-Acid Sequence : | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Glu-Lys-Ala-Leu. |
Endotoxin : | Less than 0.1ng/µg (1 IEU/µg) determined by LAL test. |
Form : | The protein was lyophilized after extensive dialysis against 20mM Phosphate buffer, pH7.4. |
Reconstitution : | It is recommended to quick spin followed by reconstitution of rHuIL-1F6 in PBS to a concentration no less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Storage : | Lyophilized rHuIL-1F5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution rHuIL-1F6 should be stored at 4°C between 2-7 days and for future use below -18°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles. |
Tag : | Non |
Gene Name : | IL1F6 interleukin 1 family, member 6 (epsilon) [ Homo sapiens ] |
Official Symbol : | IL1F6 |
Synonyms : | IL1F6; interleukin 1 family, member 6 (epsilon); FIL1; FIL1E; IL-1F6; MGC129552; MGC129553; IL1(EPSIL- ON); FIL1(EPSILON); interleukin-1 family member 6 ; FIL1 epsilon ; IL-1 epsilon ; OTTHUMP00000203688 ; interleukin-1 epsilon ; IL-1F6 (FIL-1-epsilon) ; interleukin 1, epsilon ; Interleukin-1 epsilon |
Gene ID : | 27179 |
mRNA Refseq : | NM_014440 |
Protein Refseq : | NP_055255 |
MIM : | 605509 |
UniProt ID : | Q9UHA7 |
Chromosome Location : | 2q12-q14.1 |
Function : | cytokine activity; interleukin-1 receptor binding |
Products Types
◆ Recombinant Protein | ||
Il36a-249M | Active Recombinant Mouse Il36a Protein (Met1-His160), C-His tagged, Animal-free, Carrier-free | +Inquiry |
Il36a-196M | Recombinant Active Mouse IL36A Protein, His-tagged(C-ter) | +Inquiry |
IL36A-195H | Recombinant Active Human IL36A Protein, His-tagged(C-ter) | +Inquiry |
Il36a-3506M | Recombinant Mouse Il36a Protein, Myc/DDK-tagged | +Inquiry |
IL36A-507H | Active Recombinant Human IL36A protein(Ala6-Phe158) | +Inquiry |
◆ Lysates | ||
IL36A-5238HCL | Recombinant Human IL1F6 293 Cell Lysate | +Inquiry |
Related Gene
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewWhen conducting experiments with HSP90AA1, clear and reliable interpretation of results can be obtained.
The IL36A product has low endotoxin levels and does not interfere with experimental results.
IL36A has important application value in the field of drug research and development, and has achieved certain research results.
Q&As (6)
Ask a questionIn general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.
The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.
IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.
IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.
The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.
Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.
Ask a Question for All IL36A Products
Required fields are marked with *
My Review for All IL36A Products
Required fields are marked with *
Inquiry Basket