IL37 Protein


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Official Full Name interleukin 37
Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonyms interleukin 1 family, member 7 (zeta); Interleukin-1-related protein; FIL1Z; FIL1 zeta; IL-1 zeta; IL-1H4; IL-1RP1; IL-1X protein; IL1H4; IL1RP1; interleukin 1 family member 7; FIL1; interleukin 1, zeta; FIL1(ZETA); interleukin-1 family member 7; Interleukin-1 homolog 4; interleukin-1 superfamily z; Interleukin-1 zeta; IL-1X; IL-37; IL1F7; IL-1F7; interleukin-23; OTTHUMP00000162032; OTTHUMP00000162033; OTTHUMP00000162034; OTTHUMP00000162035; OTTHUMP00000162036; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL1F7 (canonical product IL-1F7b); interleukin 37; IL37; IL-1H
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Human Cells
    • Mammalian cells
    • Tag :
    • Flag
    • GST
    • His
    • His(C-ter)
    • Met
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL37-853H Active Recombinant Human IL37 E.coli Met Inquiry
    Human IL1F7-14171H Recombinant Human IL1F7, GST-tagged E.coli GST Inquiry
    Human IL1F7-159H Recombinant Human Interleukin 1 Family, Member 7, His-tagged E.coli His Inquiry
    Human IL37-142H Recombinant Human IL37 protein E.coli N/A Inquiry
    Human IL37-370H Recombinant Human IL37, His-tagged E.coli His Inquiry
    Human IL37-753H Recombinant Human IL37 protein E.coli N/A Inquiry
    Human IL37-7843H Recombinant Human IL37 E.coli N/A Inquiry
    Human IL1F7-318H Recombinant Human IL1F7 E.coli N/A Inquiry
    Human IL37-5237HCL Recombinant Human IL1F7 293 Cell Lysate HEK293 N/A Inquiry
    Human IL37-108H Recombinant Human IL37 Protein E.coli Inquiry
    Human IL37-151H Recombinant Human IL37 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK Inquiry
    Human IL37-201H Recombinant Active Human IL37 Protein, His-tagged(C-ter) E.coli His(C-ter) Inquiry
    Human IL37-949HFL Recombinant Full Length Human IL37 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Human IL37-159H Recombinant Human IL37 protein, His-tagged E.coli His Inquiry

    IL37 involved in several pathways and played different roles in them. We selected most pathways IL37 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL37 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    IL37 has several biochemical functions, for example, cytokine activity, interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL37 itself. We selected most functions IL37 had, and list some proteins which have the same functions with IL37. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IFNA7; SPAW; IL15L; BMP3; IFNG1-1; CCL4; Ctf2; IL33; IL17F; GM13287
    interleukin-1 receptor binding IL36B; IL36G; TLR9; IL1RAP; IRAK4; IL37; IL1F10; IL36RN; TRIP6; IL1B

    IL37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL37 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL37.


    Hu, ZL; Chen, ZY; et al. Expression, purification of IL-38 in Escherichia coli and production of polyclonal antibodies. PROTEIN EXPRESSION AND PURIFICATION 107:76-82(2015).
    Lee, KW; Kim, DK; et al. Immune modulation by Bacillus subtilis-based direct-fed microbials in commercial broiler chickens. ANIMAL FEED SCIENCE AND TECHNOLOGY 200:76-85(2015).

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