Active Recombinant Human IL9 Protein

• Cat.No.: IL9-192H
• Product Overview: Recombinant Human IL9 Protein without tag was expressed in E. coli.

Specification

• Description: Interleukin 9 (IL-9) is a cytokine produced by type 2 T helper (Th2) cells and regulates hematopoietic cells. IL-9 signals through the interleukin 9 receptor (IL9R) to activate STAT signaling. IL-9 functions to induce cell proliferation, prevent cell apoptosis, and is associated with asthma and airway hyperresponsiveness.
• Source: E. coli
• Species: Human
• Bio-activity: MO7e cell proliferation, ≤2 ng/mL
• Molecular Mass: Monomer, 14.3 kDa (127 aa)
• AA Sequence: MQGCPTLAGILDINFLINKMQEDPA SKCHCSANVTSCLCLGIPSDNCTRP CFSERLSQMTNTTMQTRYPLIFSRV KKSVEVLKNNKCPYFSCEQPCNQTT AGNALTFLKSLLEIFQKEKMRGMRG KI
• Endotoxin: ≤1 EUs/μg, Kinetic LAL
• Purity: ≥95%, Reducing and Non-Reducing SDS PAGE
• Stability: 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
  1 month when stored at 4 centigrade after reconstituting as directed.
  3 months when stored at -20 to -80 centigrade after reconstituting as directed.
• Storage: Storage Prior to Reconstitution: -20 centigrade
• Storage Buffer: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
• Reconstitution: Sterile water at 0.1 mg/mL
• Shipping: Room temperature
• Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.

Gene Information

• Gene Name: IL9 interleukin 9 [ Homo sapiens (human) ]
• Official Symbol: IL9
• Synonyms: IL9; interleukin 9; interleukin-9; homolog of mouse T cell and mast cell growth factor 40; HP40; IL 9; P40; p40 cytokine; p40 T cell and mast cell growth factor; T cell growth factor p40; cytokine P40; T-cell growth factor p40; p40 T-cell and mast cell growth factor; IL-9
• Gene ID: 3578
• mRNA Refseq: NM_000590
• Protein Refseq: NP_000581
• MIM: 146931
• UniProt ID: P15248

Reviews

08/04/2022

The anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.

04/14/2019

This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.

02/28/2019

The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.

Q&As

How is the clinical trial of IL9 progressing?

Several clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.

How to obtain IL9?

IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.

What is the action mechanism of IL9?

By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.

Howthe relationship between IL9 and other related cytokines?

IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.

What are the clinical applications of IL9?

IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.

What is the mechanism of action of IL9 in the treatment of asthma?

The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.