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Recombinant Human Interleukin 9, HQ-tagged
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Cat.No. : | IL9-5342H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant humanIL9 contains 127 amino acids and a 16 aa HQ tag. Total length is 143 aa. |
Description : | Interleukin 9, alsoknown as IL9, is a cytokine (cell signalling molecule) belonging to the groupof interleukins. The protein encoded by this gene is a cytokine produced byT-cells and specifically by CD4+ helper cells that acts as a regulator of avariety of hematopoietic cells. This cytokine stimulates cell proliferationand prevents apoptosis. It functions through the interleukin-9 receptor(IL9R), which activates different signal transducer and activator (STAT)proteins and thus connects this cytokine to various biological processes. Thegene encoding this cytokine has been identified as a candidate gene forasthma. |
Source : | Hordeum vulgare(barley grain) |
Species : | Human |
Form : | Lyophilized from a0.2 µm sterile filtered solution of PBS, pH 7.2. |
Molecular Weight : | Predicted MW 16.2kDa. The glycosylated recombinant protein migrates as 3 bands with anapparent MW 20, 22 and 24 kDa in SDS-PAGE. |
Purity : | >95% by SDS-PAGE.Purified product carries no pyrogenic or pro-inflammatory contaminants, asassayed with monocyte activation test using custom human Multiplex CytokineAssay measuring IL-6, TNF-alpha and IL-1beta induction. |
Endotoxin Level : | < 0.005 ng perµg of product (0.05 EU/µg) as measured by turbidimetric kinetic assay. |
Biological Activity : | Bioactivity is assayed by measuring the dosedependent effect of human IL9 on proliferation of mouse TS1h9RA3 cell line,transfected with human IL9 receptor. The ED50 for a typical batch of recombinanthuman IL9, is 0.1 ng/ml. |
Reconstitution : | Centrifuge vial prior to opening. First add steriledistilled water to the vial to fully solubilize the protein to aconcentration not less than 100 µg/ml. After complete solubilization of theprotein, it can be further diluted to other aqueous solutions. |
Storage : | The lyophilizedprotein, though stable at room temperature for two weeks, is best stored at-20°C. Reconstituted protein should be used immediately or stored in workingaliquots at -20°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | IL9 |
Gene Name : | IL9 interleukin 9 [ Homosapiens ] |
Synonyms : | IL9; interleukin 9;P40; HP40; IL-9; interleukin-9; Cytokine P40; cytokine P40; p40 cytokine; OTTHUMP00000159423;T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog ofmouse T cell and mast cell growth factor 40 |
Gene ID : | 3578 |
mRNA Refseq : | NM_000590 |
Protein Refseq : | NP_000581 |
MIM : | 146931 |
UniProt ID : | P15248 |
Chromosome Location : | 5q31.1 |
Pathway : | Asthma;Cytokine-cytokine receptor interaction; IL-9 Signaling Pathway; Jak-STATsignaling pathway |
Function : | cytokine activity;growth factor activity; interleukin-9 receptor binding |
◆ Recombinant Protein
IL9-5165H | Recombinant Human IL9 Protein, GST-tagged | +Inquiry |
IL9-858M | Recombinant Mouse IL9 Protein (Met1-Pro144), His-tagged | +Inquiry |
IL9-192H | Recombinant Human IL9 Protein | +Inquiry |
Il9-119M | Recombinant Mouse Il9 Protein | +Inquiry |
IL9-2328R | Recombinant Rhesus monkey IL9 Protein, His-tagged | +Inquiry |
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◆ Lysates
IL9-618HCL | Recombinant Human IL9 cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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