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Active Recombinant Mouse Interleukin 9

Cat.No. : Il9-477M
Product Overview : Recombinant Mouse IL-9 produced in E.Coli is a non-glycosylated, single polypeptide chain containing 127amino acids and having a molecular mass of 14,298 Daltons.
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Cat. No. : Il9-477M
Description : Interleukin (IL)-9 is known to regulate many cell types involved in T-helper type 2 responses classically associated with asthma, including B- and T-lymphocytes, mast cells, eosinophils and epithelial cells. Growing evidence obtained from human genomic analysis and antigen-challenged transgenic mice suggests that interleukin-9 (IL-9) is a candidate factor in immunoglobulin E (IgE) production and thus is thought to be associated with bronchial inflammation and bronchial hyperresponsiveness (BHR).
Species : Mouse
Source : E.coli
Form : Lyophilized from 10mM Sodium Phosphate, pH 7.5
Purity : Purity Greater than 96% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity : Recombinant mouse IL-9 is fully bioactive when compared to a standard. Mouse IL-9 induces a dose-dependent proliferation of mouse Mo7e cells with an ED50 of 0.382 ng/ml.
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 96% as determined by : Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by : UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level : Endotoxin level is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence : MQRCSTTWGI RDTNYLIENL KDDPPSKCSC SGNVTSCLCL SVPTDDCTTP CYREGLLQLT NATQKSRLLP VFHRVKRIVE VLKNITCPSF SCEKPCNQTM AGNTMSFLKS LLGTFQKTEM QRQKSRP
Storage : Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Gene Name : Il9 interleukin 9 [ Mus musculus ]
Official Symbol : Il9
Synonyms : Il9; interleukin 9; P40; Il-9; interleukin-9; cytokine P40; T-cell growth factor P40; IL-9; homolog of mouse T cell and mast cell growth factor 40; HP40; p40 cytokine; p40 cytokine; p40 T-cell and mast cell growth factor
Gene ID : 16198
mRNA Refseq : NM_008373
Protein Refseq : NP_032399
UniProt ID : P15247
Chromosome Location : 13 B1; 13 35.0 cM
Pathway : Asthma; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function : cytokine activity; cytokine receptor binding; growth factor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How is the clinical trial of IL9 progressing? 09/05/2022

Several clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.

How to obtain IL9? 03/13/2022

IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.

What is the action mechanism of IL9? 09/22/2021

By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.

Howthe relationship between IL9 and other related cytokines? 05/02/2020

IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.

What are the clinical applications of IL9? 09/26/2019

IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.

What is the mechanism of action of IL9 in the treatment of asthma? 01/11/2019

The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.

Customer Reviews (3)

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Reviews
08/04/2022

    The anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.

    04/14/2019

      This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.

      02/28/2019

        The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.

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