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Recombinant Human IL9 Protein, His-tagged

Cat.No. : IL9-2327H
Product Overview : Recombinant Human IL9 Protein (Gln19-Ile144) with a N-His tag was expressed in E. coli.
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Description : The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Source : E. coli
Species : Human
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 17.8 kDa
Accurate Molecular Mass: 18 kDa
Protein length : Gln19-Ile144
Endotoxin : <1.0 EU per 1µg (determined by the LAL method).
Purity : > 95%
Applications : Cell culture; Activity Assays.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : IL9 interleukin 9 [ Homo sapiens (human) ]
Official Symbol : IL9
Synonyms : IL9; interleukin 9; interleukin-9; homolog of mouse T cell and mast cell growth factor 40; HP40; IL 9; P40; p40 cytokine; p40 T cell and mast cell growth factor; T cell growth factor p40; cytokine P40; T-cell growth factor p40; p40 T-cell and mast cell growth factor; IL-9;
Gene ID : 3578
mRNA Refseq : NM_000590
Protein Refseq : NP_000581
MIM : 146931
UniProt ID : P15248

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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How is the clinical trial of IL9 progressing? 09/05/2022

Several clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.

How to obtain IL9? 03/13/2022

IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.

What is the action mechanism of IL9? 09/22/2021

By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.

Howthe relationship between IL9 and other related cytokines? 05/02/2020

IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.

What are the clinical applications of IL9? 09/26/2019

IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.

What is the mechanism of action of IL9 in the treatment of asthma? 01/11/2019

The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.

Customer Reviews (3)

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Reviews
08/04/2022

    The anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.

    04/14/2019

      This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.

      02/28/2019

        The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.

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