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Recombinant Human IL9, His-tagged
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Cat.No. : | IL9-28162TH Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant full length Human IL9 with His tag produced in the endosperm tissue of barley grain ; 143 amino acids with tag, Predicted MWt 16.2 kDa. |
Description : | The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. |
Conjugation : | HIS |
Biological activity : | Bioactivity is assayed by measuring the dose dependent effect of Human IL9 on proliferation of murine TS1h9RA3 cell line, transfected with Human IL9 receptor (Renauld & Van Snick, Curr. Prot. in Immunol.2002). The ED50 for this batch is 120 pg/ml. |
Form : | Lyophilised:Reconstitute the lyophilized protein in sterile water, to a concentration of no less than 100 μg/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: PBS |
Storage : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. |
Sequence Similarities : | Belongs to the IL-7/IL-9 family. |
Gene Name : | IL9 interleukin 9 [ Homo sapiens ] |
Official Symbol : | IL9 |
Synonyms : | IL9; interleukin 9; interleukin-9; homolog of mouse T cell and mast cell growth factor 40; HP40; IL 9; P40; p40 cytokine; p40 T cell and mast cell growth factor; T cell growth factor p40; |
Gene ID : | 3578 |
mRNA Refseq : | NM_000590 |
Protein Refseq : | NP_000581 |
MIM : | 146931 |
Uniprot ID : | P15248 |
Chromosome Location : | 5q31-q35 |
Pathway : | Asthma, organism-specific biosystem; Asthma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL-9 Signaling Pathway, organism-specific biosystem; |
Function : | cytokine activity; growth factor activity; interleukin-9 receptor binding; |
◆ Recombinant Protein
Il9-219M | Recombinant Active Mouse IL9 Protein, His-tagged(N-ter) | +Inquiry |
Il9-1059M | Recombinant Mouse Il9 Protein, His-tagged | +Inquiry |
IL9-858M | Recombinant Mouse IL9 Protein (Met1-Pro144), His-tagged | +Inquiry |
IL9-218H | Recombinant Active Human IL9 Protein, His-tagged(N-ter) | +Inquiry |
IL9-2327H | Recombinant Human IL9 Protein, His-tagged | +Inquiry |
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◆ Lysates
IL9-618HCL | Recombinant Human IL9 cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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