Recombinant Human IL9, His-tagged
Cat.No. : | IL9-28162TH |
Product Overview : | Recombinant full length Human IL9 with His tag produced in the endosperm tissue of barley grain ; 143 amino acids with tag, Predicted MWt 16.2 kDa. |
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Description : | The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. |
Conjugation : | HIS |
Biological activity : | Bioactivity is assayed by measuring the dose dependent effect of Human IL9 on proliferation of murine TS1h9RA3 cell line, transfected with Human IL9 receptor (Renauld & Van Snick, Curr. Prot. in Immunol.2002). The ED50 for this batch is 120 pg/ml. |
Form : | Lyophilised:Reconstitute the lyophilized protein in sterile water, to a concentration of no less than 100 μg/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: PBS |
Storage : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. |
Sequence Similarities : | Belongs to the IL-7/IL-9 family. |
Gene Name : | IL9 interleukin 9 [ Homo sapiens ] |
Official Symbol : | IL9 |
Synonyms : | IL9; interleukin 9; interleukin-9; homolog of mouse T cell and mast cell growth factor 40; HP40; IL 9; P40; p40 cytokine; p40 T cell and mast cell growth factor; T cell growth factor p40; |
Gene ID : | 3578 |
mRNA Refseq : | NM_000590 |
Protein Refseq : | NP_000581 |
MIM : | 146931 |
Uniprot ID : | P15248 |
Chromosome Location : | 5q31-q35 |
Pathway : | Asthma, organism-specific biosystem; Asthma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL-9 Signaling Pathway, organism-specific biosystem; |
Function : | cytokine activity; growth factor activity; interleukin-9 receptor binding; |
Products Types
◆ Recombinant Protein | ||
IL9-3566H | Recombinant Human IL9 protein, His-SUMO-tagged | +Inquiry |
IL9-4521M | Recombinant Mouse IL9 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL9-230I | Active Recombinant Human IL9 Protein | +Inquiry |
Il9-2175M | Recombinant Mouse Il9 Protein | +Inquiry |
Il9-3534M | Recombinant Mouse Il9 protein, hFc-tagged | +Inquiry |
◆ Lysates | ||
IL9-618HCL | Recombinant Human IL9 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThe anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.
This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.
The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.
Q&As (6)
Ask a questionSeveral clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.
IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.
By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.
IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.
IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.
The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.
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