Recombinant Human IL9, His-tagged IL9-28162TH

Recombinant Human IL9, His-tagged

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Cat.No. : IL9-28162TH Optional Service: Optional requirements on this protein
Product Overview : Recombinant full length Human IL9 with His tag produced in the endosperm tissue of barley grain ; 143 amino acids with tag, Predicted MWt 16.2 kDa.
Description : The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Conjugation : HIS
Biological activity : Bioactivity is assayed by measuring the dose dependent effect of Human IL9 on proliferation of murine TS1h9RA3 cell line, transfected with Human IL9 receptor (Renauld & Van Snick, Curr. Prot. in Immunol.2002). The ED50 for this batch is 120 pg/ml.
Form : Lyophilised:Reconstitute the lyophilized protein in sterile water, to a concentration of no less than 100 μg/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: PBS
Storage : The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
Sequence Similarities : Belongs to the IL-7/IL-9 family.
Gene Name : IL9 interleukin 9 [ Homo sapiens ]
Official Symbol : IL9
Synonyms : IL9; interleukin 9; interleukin-9; homolog of mouse T cell and mast cell growth factor 40; HP40; IL 9; P40; p40 cytokine; p40 T cell and mast cell growth factor; T cell growth factor p40;
Gene ID : 3578
mRNA Refseq : NM_000590
Protein Refseq : NP_000581
MIM : 146931
Uniprot ID : P15248
Chromosome Location : 5q31-q35
Pathway : Asthma, organism-specific biosystem; Asthma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL-9 Signaling Pathway, organism-specific biosystem;
Function : cytokine activity; growth factor activity; interleukin-9 receptor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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