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MPZ

  • Official Full Name

    myelin protein zero

  • Overview

    This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. [provided by RefSeq, Apr 2010]
  • Synonyms

    MPZ; myelin protein zero; P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB; myelin protein P0; myelin peripheral protein; Charcot-Marie-Tooth neuropathy 1B;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Gallus gallus (Chicken)
  • Heterodontus francisci (Horn shark) (Cestracion francisci)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MPZ-8493H Recombinant Human MPZ protein, His-tagged HEK293 His Ile30-Arg153
Human MPZ-3902H Recombinant Human MPZ protein, MYC/DDK-tagged HEK293 Myc/DDK
Human MPZ-2294H Recombinant Human MPZ protein, His-tagged E.coli His Ile30~Lys248
Human MPZ-29152TH Recombinant Human MPZ Wheat Germ N/A 258 amino acids
Human MPZ-4219HCL Recombinant Human MPZ 293 Cell Lysate HEK293 N/A
Human MPZ-5524H Recombinant Human MPZ Protein, GST-tagged Wheat Germ GST
Human MPZ-6337HF Recombinant Full Length Human MPZ Protein, GST-tagged In Vitro Cell Free System GST 258 amino acids
Human MPZ-4600H Recombinant Human MPZ Protein (Ile30-Lys248), His tagged E.coli His Ile30-Lys248
Human MPZ-1461H Recombinant Human MPZ Protein (30-156 aa), His-tagged Yeast His 30-156 aa
Human MPZ-314HF Recombinant Full Length Human MPZ Protein In Vitro Cell Free System 258 amino acids
Human MPZ-4599H Recombinant Human MPZ Protein (Ile30-Arg153), C-His tagged Mammalian cells C-His Ile30-Arg153
Human MPZ-1218H Recombinant Human MPZ Protein (30-156 aa), GST-tagged E.coli GST 30-156 aa
Human MPZ-3239H Recombinant Human MPZ protein, His-tagged E.coli His 30-156aa
Mouse Mpz-4131M Recombinant Mouse Mpz Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat MPZ-3744R Recombinant Rat MPZ Protein Mammalian Cell His
Rat Mpz-1791R Recombinant Rat Mpz Protein, His&GST-tagged E.coli N-His&GST Ile30-Lys248
Rat MPZ-3402R-B Recombinant Rat MPZ Protein Pre-coupled Magnetic Beads HEK293
Rat MPZ-3402R Recombinant Rat MPZ Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL31068BF Recombinant Full Length Bovine Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-248)
Gallus gallus (Chicken) RFL34972GF Recombinant Full Length Chicken Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-249)
Heterodontus francisci (Horn shark) (Cestracion francisci) RFL15417HF Recombinant Full Length Heterodontus Francisci Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (28-246)
Homo sapiens (Human) RFL16682HF Recombinant Full Length Human Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-248)
Mus musculus (Mouse) RFL29226MF Recombinant Full Length Mouse Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-248)
Rattus norvegicus (Rat) RFL13370RF Recombinant Full Length Rat Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-248)
Xenopus laevis (African clawed frog) RFL19715XF Recombinant Full Length Xenopus Laevis Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-245)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL22345XF Recombinant Full Length Xenopus Tropicalis Myelin Protein P0(Mpz) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-243)
Zebrafish MPZ-9712Z Recombinant Zebrafish MPZ Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MPZ Related Articles

MPZ involved in several pathways and played different roles in them. We selected most pathways MPZ participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with MPZ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)CD8A;PTPRF;CNTNAP2;NLGN4A;HLA-DMA;HLA-A;CLDNJ;JAM2A;PVRL3B

MPZ has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MPZ itself. We selected most functions MPZ had, and list some proteins which have the same functions with MPZ. You can find most of the proteins on our site.

Function Related Protein
structural molecule activityCLDNB;PRPH;ODF2;CSTA;FGA;RLN3B;KRT77;LAMB2;KRT4

MPZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPZ here. Most of them are supplied by our site. Hope this information will be useful for your research of MPZ.

CCP110; PSMB3; PINX1

Yamaguchi, Y; Hayashi, A; et al. L-MPZ, a Novel Isoform of Myelin P0, Is Produced by Stop Codon Readthrough. JOURNAL OF BIOLOGICAL CHEMISTRY 287:17765-17776(2012).
Bai, Q; Sun, M; et al. Major Isoform of Zebrafish P0 Is a 23.5 KDa Myelin Glycoprotein Expressed in Selected White Matter Tracts of the Central Nervous System. JOURNAL OF COMPARATIVE NEUROLOGY 519:1580-1596(2011).
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