Official Full Name
BackgroundNeurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on certain neurons of the peripheral and central nervous system; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses. NT-3 was the third neurotrophic factor to be characterized, after nerve growth factor (NGF) and BDNF (Brain Derived Neurotrophic Factor).
SynonymsNtf3; neurotrophin 3; neurotrophin-3; HDNF; NT-3; NGF-2; neurotrophic factor; nerve growth factor 2; neurotrophin-3 (HDNF/NT-3); NT3; NGF2;