NTF3

  • Official Full Name

    neurotrophin 3

  • Overview

    Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on certain neurons of the peripheral and central nervous system; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses. NT-3 was the third neurotrophic factor to be characterized, after nerve growth factor (NGF) and BDNF (Brain Derived Neurotrophic Factor).
  • Synonyms

    Ntf3; neurotrophin 3; neurotrophin-3; HDNF; NT-3; NGF-2; neurotrophic factor; nerve growth factor 2; neurotrophin-3 (HDNF/NT-3); NT3; NGF2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Native Proteins
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human/Mouse
  • Mouse
  • Rat
  • CHO
  • E.coli
  • HEK293
  • Human
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mouse
  • Sf21 Insect Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
  • N
  • Strep II
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NTF3-011H Active Recombinant Human NTF3(139-257aa) Human N/A
Human NTF3-15H Active Recombinant Human Neurotrophin 3 HEK293 N/A
Human NTF3-044H Active Recombinant Human Neurotrophin 3 Human N/A
Human NTF3-012H Active Recombinant Human NTF3(full-length) Human N/A
Human NTF3-3621H Recombinant Human Neurotrophin 3 E.coli N/A
Human NTF3-16H Recombinant Human NTF3, StrepII-tagged Human Cell Strep II 19-257, 239 a.a.
Human NTF3-22H Recombinant Human Neurotrophin 3 Sf21 Insect Cell N/A
Human NTF3-751H Recombinant Human NTF3 protein, His-tagged E.coli His Met21~Arg138 (Accession# P20783)
Human NTF3-128H Recombinant Human 3 -Nucleotidase E.coli N/A
Human NTF3-3670HCL Recombinant Human NTF3 293 Cell Lysate HEK293 N/A
Human NTF3-3671HCL Recombinant Human NTF3 293 Cell Lysate HEK293 N/A
Human NTF3-088H Active Recombinant Human NTF3 Protein E.coli
Human NTF3-118HG Active GMP Recombinant Human NTF3 Protein Insect Cell N/A
Human NTF3-1516H Recombinant Human NTF3 protein, His&Myc-tagged Insect Cell His&Myc 139-257aa
Human NTF3-29249TH Native Human NTF3 E.coli N/A
Human NTF3-30H Recombinant Human/Mouse/Rat/Porcine NTF3 Protein E.coli
Human NTF3-1473H Recombinant Human NTF3 protein, His&Myc-tagged HEK293 His&Myc 139-257aa
Human NTF3-4742H Recombinant Human NTF3 Protein (Asn19-Thr257) E.coli Tag Free Asn19-Thr257
Human NTF3-2701H Recombinant Human NTF3 Protein (Met21-Arg138), His tagged E.coli His Met21-Arg138
Human NT3-01H Active Recombinant Human NTF3 Protein Insect Cell 139-257
Human NTF3-146H Recombinant Human NTF3 Protein E.coli
Human NTF3-170H Neurotrophin 3 Reference standard CHO N/A
Mouse Ntf3-018M Active Recombinant Mouse Neurotrophin 3 Mouse N/A
Mouse NTF3-10933M Recombinant Mouse NTF3 Protein Mammalian Cell His
Mouse NTF3-6233M Recombinant Mouse NTF3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ntf3-1867M Recombinant Mouse Ntf3 Protein, His-tagged E.coli N-His Met21-Arg139
Mouse NTF3-6233M-B Recombinant Mouse NTF3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Ntf3-1868M Recombinant Mouse Ntf3 Protein, His-tagged E.coli N-His Ala130-Gly255
Rat NTF3-4098R Recombinant Rat NTF3 Protein Mammalian Cell His
Rat Ntf3-1869R Recombinant Rat Ntf3 Protein, His-tagged E.coli N-His Thr130-Gly256
Rat NTF3-3759R-B Recombinant Rat NTF3 Protein Pre-coupled Magnetic Beads HEK293
Rat NTF3-3759R Recombinant Rat NTF3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human/Mouse NTF3-216H Recombinant Human/Mouse NTF3 Protein E.coli
Human/Mouse NTF3-217H Recombinant Human/Mouse NTF3 Protein E.coli
Human/Mouse NTF3-218H Recombinant Human/Mouse NTF3 Protein E.coli
Chicken NTF3-3135C Recombinant Chicken NTF3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

NTF3 involved in several pathways and played different roles in them. We selected most pathways NTF3 participated on our site, such as MAPK signaling pathway, Neurotrophin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NTF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayFGF11;TAB2;NFATC3;IL1A;GADD45B;RASA1;FGFR3;FGF6;RPS6KA4
Neurotrophin signaling pathwayMAP3K3;MAPK13;NFKBIB;MAGED1;RAC1;ZFP110;MAPK10;PTPN11;NFKBIA

NTF3 has several biochemical functions, for example, chemoattractant activity, growth factor activity, neurotrophin p75 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NTF3 itself. We selected most functions NTF3 had, and list some proteins which have the same functions with NTF3. You can find most of the proteins on our site.

Function Related Protein
chemoattractant activityCCL3;PDGFB;VEGFB;FGF10;VHL;FIGF;HMGB2;MIF;HMGB1
growth factor activityTHPO;EFEMP1;FGF12B;INHBE;HBEGF;GDF10;TIMP1;INHBB;PDGFAA
neurotrophin p75 receptor bindingNTRK1;ZFP110;NTF3;NRADD
protein bindingTMEM140;XRCC1;NKD1;SGTA;CCDC22;SRC;CFLAR;MUC7;ATG4A
receptor bindingAPP;FGF20A;DRD1A;WNT7A;TNFSF13B;FZD1;NRG1;KNG1;SLC27A2

NTF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NTF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NTF3.

MEOX2; BDNF; SORCS2

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