Active Recombinant Human NTF3 Protein

• Cat.No.: NTF3-088H
• Product Overview: Recombinant Human NTF3 Protein (120 aa) without tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
• Source: E. coli
• Species: Human
• Bio-activity: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/mL, corresponding to a specific activity of 2-5 x 104 units/mg.
• Molecular Mass: 13.6 kD as monomer, 26.5 kD as dimer
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: NTF3 neurotrophin 3 [ Homo sapiens (human) ]
• Official Symbol: NTF3
• Synonyms: NTF3; neurotrophin 3; NT3; HDNF; NGF2; NT-3; NGF-2; neurotrophin-3; Names; nerve growth factor 2; neurotrophic factor
• Gene ID: 4908
• mRNA Refseq: NM_002527
• Protein Refseq: NP_002518
• MIM: 162660
• UniProt ID: P20783