Active Recombinant Human Neurotrophin 3
| Cat.No. : | NTF3-044H |
| Product Overview : | Recombinant human NT-3 was expressed in E. coli and purified by SDS PAGE and HPLC, 13.6 KDa. |
- Specification
- Gene Information
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| Cat. No. : | NTF3-044H |
| Description : | NT-3 is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, Mouse and rat NT-3 are identical. |
| Source : | Human |
| Host : | E.coli |
| Form : | Supplied lyophilized with no additives. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Allow to set for at least 30 minutes, mix well. |
| Purity : | > 98% pure by SDS PAGE and HPLC |
| Sequence : | Region of NT3 protein corresponding to amino acids MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT. |
| Molecular Mass : | 13.6 kDa |
| Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
| Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
| Bioactivity : | The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml. |
| Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
| Gene Name : | NTF3 neurotrophin 3 [ Homo sapiens ] |
| Official Symbol : | NTF3 |
| Synonyms : | neurotrophin 3; NT3; HDNF; NGF2; NGF-2; MGC129711; NTF3; NT-3; Nerve growth factor 2; Neurotrophic factor |
| Gene ID : | 4908 |
| mRNA Refseq : | NM_001102654 |
| Protein Refseq : | NP_001096124 |
| MIM : | 162660 |
| UniProt ID : | P20783 |
| Chromosome Location : | 12p13 |
| Pathway : | MAPK signaling pathway; Neurotrophic factor-mediated Trk receptor signaling; Neurotrophin signaling pathway; Trk receptor signaling mediated by the MAPK pathway; p75(NTR)-mediated signaling |
| Function : | growth factor activity; nerve growth factor binding; neurotrophin receptor binding; receptor binding |
Products Types
| ◆ Recombinant Protein | ||
| NTF3-3759R | Recombinant Rat NTF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
| NTF3-088H | Active Recombinant Human NTF3 Protein | +Inquiry |
| NTF3-6233M | Recombinant Mouse NTF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
| NT3-01H | Active Recombinant Human NTF3 Protein | +Inquiry |
| NTF3-216H | Active Recombinant Human/Mouse NTF3 Protein | +Inquiry |
| ◆ Native Protein | ||
| NTF3-29249TH | Native Human NTF3 | +Inquiry |
| ◆ Lysates | ||
| NTF3-3671HCL | Recombinant Human NTF3 293 Cell Lysate | +Inquiry |
| NTF3-3670HCL | Recombinant Human NTF3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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