OLR1
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Official Full Name
oxidized low density lipoprotein (lectin-like) receptor 1
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Overview
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimers disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] -
Synonyms
OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; LOX1; LOXIN; SLOX1; CLEC8A; SCARE1; oxidized low-density lipoprotein receptor 1; hLOX-1; ox LDL receptor 1; lectin-type oxidized LDL receptor 1; scavenger receptor class E, member 1; C-type lectin domain family 8 member A; oxidized low-density lipoprotein receptor 1, soluble form;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Cattle
- Cynomolgus Monkey
- Homo sapiens (Human)
- Human
- Mouse
- Rabbit
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human
- Human Cell
- Insect cells
- Mammalian Cell
- Mammalian cells
- NS0
- Fc
- Flag
- GST
- His
- Avi
- T7
- Myc
- DDK
- N
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
OLR1 involved in several pathways and played different roles in them. We selected most pathways OLR1 participated on our site, such as PPAR signaling pathway, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with OLR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPAR signaling pathway | OLR1;SCD5;CYP4A10;DBI;APOA1A;ILK;FABP3;SCDB;PPARDB |
| Phagosome | TUBA3E;MHC2DEB;CALR3B;BF1;THBS4A;FCGR3B;RAB7B;FCGR2C;FCGR3 |
OLR1 has several biochemical functions, for example, carbohydrate binding, low-density lipoprotein receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OLR1 itself. We selected most functions OLR1 had, and list some proteins which have the same functions with OLR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | CLEC9A;SIGLEC14;CLEC2B;SELL;CLEC3A;ASGR1;Siglec1;NCAN;ATRN |
| low-density lipoprotein receptor activity | LRP12;CXCL16;LRP6;VLDLR;LDLR;OLR1 |
| protein binding | AHSA1;SNIP1;SPANXD;PRKAG1;FASTKD3;ZZZ3;C16orf5;GIPC1;SKP2 |
OLR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OLR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OLR1.
TCP1; CCT4; HSPA1L; CCT6A; CCT3; CCT7; q9bu08_human; M6PR; EEA1
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