Recombinant Human OLR1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: OLR1-5099H
• Product Overview: OLR1 MS Standard C13 and N15-labeled recombinant protein (NP_002534) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 31 kDa
• AA Sequence: MTFDDLKIQTVKDQPDEKSNGKKAK GLQFLYSPWWCLAAATLGVLCLGLV VTIMVLGMQLSQVSDLLTQEQANLT HQKKKLEGQISARQQAEEASQESEN ELKEMIETLARKLNEKSKEQMELHH QNLNLQETLKRVANCSAPCPQDWIW HGENCYLFSSGSFNWEKSQEKCLSL DAKLLKINSTADLDFIQQAISYSSF PFWMGLSRRNPSYPWLWEDGSPLMP HLFRVRGAVSQTYPSGTCAYIQRGA VYAENCILAAFSICQKKANLRAQTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: OLR1 oxidized low density lipoprotein receptor 1 [ Homo sapiens (human) ]
• Official Symbol: OLR1
• Synonyms: OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidised low density lipoprotein (lectin like) receptor 1; oxidized low-density lipoprotein receptor 1; CLEC8A; LOX 1; SCARE1; hLOX-1; ox LDL receptor 1; lectin-type oxidized LDL receptor 1; scavenger receptor class E, member 1; C-type lectin domain family 8 member A; oxidized low-density lipoprotein receptor 1, soluble form; LOX1; LOXIN; SLOX1
• Gene ID: 4973
• mRNA Refseq: NM_002543
• Protein Refseq: NP_002534
• MIM: 602601
• UniProt ID: P78380