| Cat.No. : |
OLR1-01H |
| Product Overview : |
Recombinant human OLR1 (58-273aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Description : |
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. |
| Source : |
Insect cells |
| Species : |
Human |
| Tag : |
His |
| Form : |
Liquid |
| Molecular Mass : |
25.8 kDa (225aa) |
| AA Sequence : |
ADPMQLSQVS DLLTQEQANL THQKKKLEGQ ISARQQAEEA SQESENELKE MIETLARKLN EKSKEQMELH HQNLNLQETL KRVANCSAPC PQDWIWHGEN CYLFSSGSFN WEKSQEKCLS LDAKLLKINS TADLDFIQQA ISYSSFPFWM GLSRRNPSYP WLWEDGSPLM PHLFRVRGAV SQTYPSGTCA YIQRGAVYAE NCILAAFSIC QKKANLRAQH HHHHH |
| Endotoxin : |
< 1.0 EU/μg of the protein by the LAL method. |
| Purity : |
> 95% as analyzed by SDS-PAGE |
| Applications : |
SDS-PAGE |
| Storage : |
Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : |
1 mg/mL (determined by absorbance at 280nm) |
| Storage Buffer : |
Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
| SDS-PAGE : |
3 μg by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
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