Recombinant Human OLR1

• Cat.No.: OLR1-3631H
• Product Overview: Recombinant human OLR1 protein was expressed in E.coli (58-273aa).

Specification

• Species: Human
• Source: Human
• Tag: Non
• Protein Length: 58-273 a.a.
• Description: OLR1, also known as oxidized low density lipoprotein(Ox-LDL) receptor 1, is a type II membrane protein that is a member of the C-type lectin family and acts as a cell-surface receptor for Ox-LDL. Ox-LDL plays a role in early ather-osclerosis, which includes the transformation of monocyte-derived macro-phages to foam cells in atherosclerotic lesions. This protein may also trigger the activation of the NFμB signal transduction pathway.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 5% glycerol, 0.4M Urea.
• Molecular Weight: 24.7 kDa (216aa)
• Purity: > 90% by SDS - PAGE
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MQLSQVSDLL TQEQANLTHQ KKKLEGQISA RQQAEEASQE SENELKEMIE TLARKLNEKS KEQMELHHQN LNLQETLKRV ANCSAPCPQD WIWHGENCYL FSSGSFNWEK SQEKCLSLDA KLLKINSTAD LDFIQQAISY SSFPFWMGLS RRNPSYPWLW EDGSPLMPHL FRVRGAVSQT YPSGTCAYIQ RGAVYAENCI LAAFSICQKK ANLRAQ
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: PPAR signaling pathway

Gene Information

• Gene Name: OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 [ Homo sapiens ]
• Official Symbol: OLR1
• Synonyms: OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; LOX1; LOXIN; SLOX1; CLEC8A; SCARE1; oxidized low-density lipoprotein receptor 1; hLOX-1; ox LDL receptor 1; lectin-type oxidized LDL receptor 1; scavenger receptor class E, member 1; C-type lectin domain family 8 member A; oxidized low-density lipoprotein receptor 1, soluble form; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; LOX-1; Oxidized low-density lipoprotein receptor 1, soluble form
• Gene ID: 4973
• mRNA Refseq: NM_001172632
• Protein Refseq: NP_001166103
• MIM: 602601
• UniProt ID: P78380
• Chromosome Location: 12p13.2-p12.3
• Function: low-density lipoprotein receptor activity; protein binding; receptor activity; sugar binding