PSCA
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Official Full Name
prostate stem cell antigen
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Overview
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. -
Synonyms
PSCA; prostate stem cell antigen; PRO232;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- E.coli
- HEK293
- Human Cells
- Yeast
- C
- His
- Avi
- Fc
- Flag
- GST
- Non
- Other Resource
PSCA involved in several pathways and played different roles in them. We selected most pathways PSCA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PSCA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
PSCA has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PSCA itself. We selected most functions PSCA had, and list some proteins which have the same functions with PSCA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
PSCA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSCA here. Most of them are supplied by our site. Hope this information will be useful for your research of PSCA.
Research Area
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Customer Reviews (3)
Write a reviewUser-friendly data analysis capabilities contributed to the product's overall value for our research.
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Q&As (7)
Ask a questionGenetic variations in PSCA have been studied, and certain polymorphisms may be associated with cancer susceptibility.
PSCA is being explored as a potential target for therapeutic interventions in prostate cancer treatment.
PSCA is often studied in the context of prostate cancer, as it is overexpressed in prostate cancer cells.
PSCA may play a role in prostate cancer progression, and its overexpression is associated with malignancy.
PSCA stands for Prostate Stem Cell Antigen.
Yes, PSCA is considered a potential biomarker for prostate cancer due to its overexpression in prostate cancer cells.
While PSCA is notably expressed in the prostate, its expression has also been reported in other tissues and organs.
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