S100A6 involved in several pathways and played different roles in them. We selected most pathways S100A6 participated on our site, such as Gastric cancer network 2, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Gastric cancer network 2 |
CHTF8; PLAC8; SNURF; CEBPZ; TOP2A; RNF144B; LBR; SNRPN; CHTF18; MTDH |
| Prostaglandin Synthesis and Regulation |
ANXA6; S100A6; CC10; S100A10; ANXA5; ANXA2; ANXA3; ANXA4 |
S100A6 has several biochemical functions, for example, S100 protein binding, calcium ion binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A6 itself. We selected most functions S100A6 had, and list some proteins which have the same functions with S100A6. You can find most of the proteins on our site.
| Function |
Related Protein |
| S100 protein binding |
FGF1A; ANXA2; EZR; ANXA11; S100B; S100A1; S100A11; DDX1; S100A6; AHNAK |
| calcium ion binding |
PLCB3; PLS1; GRIN1; PGS1; GUCA1C; F9A; AIF1; MICU2; MYL12A; CAPS |
| calcium-dependent protein binding |
MBL2; DDX5; MASP1; STX2; KOP; CHP1; CD209A; S100A6; SYN1; ANXA6 |
| ion transmembrane transporter activity |
SFXN3; SFXN5B; TRPV2; LASP1; PLP2; SFXN1; GJA1; SFXN5A; SFXN2; S100A6 |
| protein binding |
SUPT5H; TNFSF14; ITSN1; IRAK1; FOXH1; CSRNP2; FRS2; IGFBP7; ARFGAP3; EP400 |
| protein homodimerization activity |
ANXA6; MTUS2; BHLHE40; IGJ; DARS2; CHMP4A; TFRC; TSC2; HMOX1; SRGAP2A |
| tropomyosin binding |
PYCARD; TMOD1; TMOD2; NEBL; TMOD4; CALD1; LMOD2A; TNNT3; TMOD3; LMOD3 |
| zinc ion binding |
DPF2; ABLIM3; BRD1; ZSWIM1; DNPEP; CPSF4; TRIM33; CHMP1A; LHX9; ZMIZ2 |
S100A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A6.
KPNA2; PPID; FKBP4; PEX5; MDM2; S100B; TP53
Meghnani, V; Wagh, A; et al. The receptor for advanced glycation end products influences the expression of its S100 protein ligands in melanoma tumors. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 57:54-62(2014).
Jurewicz, E; Goral, A; et al. S100A6 is secreted from Wharton's jelly mesenchymal stem cells and interacts with integrin beta 1. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 55:298-303(2014).
