S100A6 Protein


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Official Full Name S100 calcium binding protein A6
Background Protein S100-A6 is a protein that in humans is encoded by the S100A6 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Synonyms S100A6; 2A9; 5B10; CABP; CACY; PRA; MLN 4; S100 calcium-binding protein A6 (calcyclin); calcyclin; growth factor-inducible protein 2A9; prolactin receptor-associated protein; protein S100-A6;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Mouse
    • Tag :
    • Flag
    • His
    • His (Fc)-Avi
    • S
    • His-SUMO
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human S100A6-1773H Recombinant Human S100A6 protein, His & S-tagged E.coli His/S Inquiry
    Human S100A6-2212H Recombinant Human S100A6, His tagged Insect Cell His
    Human S100A6-3101H Recombinant Human S100A6 protein E.coli
    Human S100A6-916H Recombinant Human S100A6, His-tagged E.coli His Inquiry
    Mouse S100A6-3100M Recombinant Mouse S100A6, None tagged E.coli N/A
    Mouse S100a6-3552M Recombinant Mouse S100a6, His-tagged Mouse His Inquiry
    Mouse S100a6-5106M Recombinant Mouse S100 calcium Binding Protein A6 (calcyclin), His-tagged Mouse His Inquiry
    Mouse S100a6-845M Recombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin) HEK293 N/A Inquiry
    Rat S100a6-1774R Recombinant Rat S100a6 protein, His-tagged E.coli His Inquiry
    Rhesus Macaque S100A6-4063R Recombinant Rhesus monkey S100A6 Protein, His-tagged Mammalian Cell His Inquiry
    Rabbit S100A6-1775R Recombinant Rabbit S100A6 protein, His-tagged E.coli His Inquiry
    Chicken S100A6-5724C Recombinant Chicken S100A6 Mammalian Cell His Inquiry
    S100a6-4566M Recombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin) Mouse N/A Inquiry
    Human S100A6-690HCL Recombinant Human S100A6 cell lysate Insect Cell N/A Inquiry
    Human S100A6-1941H Recombinant Human S100A6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human S100A6-2140HFL Recombinant Full Length Human S100A6 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Human S100A6-3462H Recombinant Human S100A6 protein, His-SUMO-tagged E.coli His-SUMO Inquiry
    Rhesus Macaque S100A6-3880R Recombinant Rhesus Macaque S100A6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human S100A6-620H Recombinant Human S100A6 Protein E.coli N/A Inquiry
    Human S100A6-228H Recombinant Human S100A6 Protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Human S100A6-4913H Recombinant Human S100A6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Mouse S100a6-43M Native Mouse S100A6 N/A Inquiry
    Mouse S100a6-5670M Recombinant Mouse S100a6 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry
    Mouse S100a6-7326M Recombinant Mouse S100a6 Protein, His-tagged E.coli His Inquiry

    S100A6 involved in several pathways and played different roles in them. We selected most pathways S100A6 participated on our site, such as Gastric cancer network 2, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gastric cancer network 2 CHTF8; PLAC8; SNURF; CEBPZ; TOP2A; RNF144B; LBR; SNRPN; CHTF18; MTDH
    Prostaglandin Synthesis and Regulation ANXA6; S100A6; CC10; S100A10; ANXA5; ANXA2; ANXA3; ANXA4

    S100A6 has several biochemical functions, for example, S100 protein binding, calcium ion binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A6 itself. We selected most functions S100A6 had, and list some proteins which have the same functions with S100A6. You can find most of the proteins on our site.

    Function Related Protein
    S100 protein binding FGF1A; ANXA2; EZR; ANXA11; S100B; S100A1; S100A11; DDX1; S100A6; AHNAK
    calcium ion binding PLCB3; PLS1; GRIN1; PGS1; GUCA1C; F9A; AIF1; MICU2; MYL12A; CAPS
    calcium-dependent protein binding MBL2; DDX5; MASP1; STX2; KOP; CHP1; CD209A; S100A6; SYN1; ANXA6
    ion transmembrane transporter activity SFXN3; SFXN5B; TRPV2; LASP1; PLP2; SFXN1; GJA1; SFXN5A; SFXN2; S100A6
    protein binding SUPT5H; TNFSF14; ITSN1; IRAK1; FOXH1; CSRNP2; FRS2; IGFBP7; ARFGAP3; EP400
    protein homodimerization activity ANXA6; MTUS2; BHLHE40; IGJ; DARS2; CHMP4A; TFRC; TSC2; HMOX1; SRGAP2A
    tropomyosin binding PYCARD; TMOD1; TMOD2; NEBL; TMOD4; CALD1; LMOD2A; TNNT3; TMOD3; LMOD3
    zinc ion binding DPF2; ABLIM3; BRD1; ZSWIM1; DNPEP; CPSF4; TRIM33; CHMP1A; LHX9; ZMIZ2

    S100A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A6.

    KPNA2; PPID; FKBP4; PEX5; MDM2; S100B; TP53

    Meghnani, V; Wagh, A; et al. The receptor for advanced glycation end products influences the expression of its S100 protein ligands in melanoma tumors. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 57:54-62(2014).
    Jurewicz, E; Goral, A; et al. S100A6 is secreted from Wharton's jelly mesenchymal stem cells and interacts with integrin beta 1. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 55:298-303(2014).

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