S100A6 Protein


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Official Full Name S100 calcium binding protein A6
Background Protein S100-A6 is a protein that in humans is encoded by the S100A6 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Synonyms S100A6; 2A9; 5B10; CABP; CACY; PRA; MLN 4; S100 calcium-binding protein A6 (calcyclin); calcyclin; growth factor-inducible protein 2A9; prolactin receptor-associated protein; protein S100-A6
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Mouse
    • Tag :
    • His
    • S
    • His-SUMO
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human S100A6-1773H Recombinant Human S100A6 protein, His & S-tagged E.coli His/S
    Human S100A6-2212H Recombinant Human S100A6, His tagged Insect Cell His
    Human S100A6-3101H Recombinant Human S100A6 protein E.coli
    Human S100A6-916H Recombinant Human S100A6, His-tagged E.coli His
    Mouse S100A6-3100M Recombinant Mouse S100A6, None tagged E.coli N/A
    Mouse S100a6-3552M Recombinant Mouse S100a6, His-tagged Mouse His
    Mouse S100a6-5106M Recombinant Mouse S100 calcium Binding Protein A6 (calcyclin), His-tagged Mouse His
    Mouse S100a6-845M Recombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin) HEK293 N/A
    Rat S100a6-1774R Recombinant Rat S100a6 protein, His-tagged E.coli His
    Rhesus Macaque S100A6-4063R Recombinant Rhesus monkey S100A6 Protein, His-tagged Mammalian Cell His
    Rabbit S100A6-1775R Recombinant Rabbit S100A6 protein, His-tagged E.coli His
    Chicken S100A6-5724C Recombinant Chicken S100A6 Mammalian Cell His
    S100a6-4566M Recombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin) Mouse N/A
    Human S100A6-690HCL Recombinant Human S100A6 cell lysate Insect Cell N/A
    Human S100A6-3462H Recombinant Human S100A6 protein, His-SUMO-tagged E.coli His-SUMO
    Human S100A6-620H Recombinant Human S100A6 Protein E.coli N/A
    Human S100A6-228H Recombinant Human S100A6 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human S100A6-4913H Recombinant Human S100A6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse S100a6-43M Native Mouse S100A6 N/A
    Mouse S100a6-5670M Recombinant Mouse S100a6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse S100a6-7326M Recombinant Mouse S100a6 Protein, His-tagged E.coli His

    S100A6 involved in several pathways and played different roles in them. We selected most pathways S100A6 participated on our site, such as Gastric cancer network 2, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gastric cancer network 2 DSCC1; PLAC8; TOP2A; ATAD2; CHTF8; S100A6; MTDH; CHTF18; RNF144B; CEBPZ
    Prostaglandin Synthesis and Regulation CC10; S100A6; ANXA5; ANXA2; ANXA3; ANXA4; S100A10; ANXA6

    S100A6 has several biochemical functions, for example, S100 protein binding, calcium ion binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A6 itself. We selected most functions S100A6 had, and list some proteins which have the same functions with S100A6. You can find most of the proteins on our site.

    Function Related Protein
    S100 protein binding ATP2A2; EZR; S100A11; FGF1; S100B; S100A6; AGER; KCNK3; DDX1; S100A1
    calcium ion binding TNNC1B; CABP5B; PCDH17; C1R; CASQ1A; ANXA4; SLC25A13; SYT9; MAN1A1; CAPS
    calcium-dependent protein binding CHP1; S100A6; C9orf9; ANXA4; RBM22; MASP1; S100A1; MMP13; KOP; S100B
    ion transmembrane transporter activity PLP2; SFXN4; SFXN3; LASP1; TRPV2; GJA1; SFXN5B; SFXN5A; SFXN1; SFXN2
    protein binding MTAP1A; FOXK2; IKZF1; NFE2L1; TBP; MAGEH1; MCEE; CDK5R1; CD70; COG1
    protein homodimerization activity CARS; BCL2L2; OXCT1; MAP3K13; NR6A1A; TFRC; CHRNA7; GRIK1; RCHY1; MAOB
    tropomyosin binding LMOD2A; TNNT1; S100A6; TMOD4; LMOD3; PYCARD; TMOD1; TNNT3; TNNT2A; CALD1
    zinc ion binding JADE1; LIMS3L; ABLIM3; BMI1; CXXC5; PDLIM5B; PIAS4B; ADAM18; MYLIPB; ZDHHC5

    S100A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A6.

    KPNA2; PPID; FKBP4; PEX5; MDM2; S100B; TP53

    Meghnani, V; Wagh, A; et al. The receptor for advanced glycation end products influences the expression of its S100 protein ligands in melanoma tumors. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 57:54-62(2014).
    Jurewicz, E; Goral, A; et al. S100A6 is secreted from Wharton's jelly mesenchymal stem cells and interacts with integrin beta 1. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 55:298-303(2014).

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