S100A6

  • Official Full Name

    S100 calcium binding protein A6

  • Overview

    Protein S100-A6 is a protein that in humans is encoded by the S100A6 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
  • Synonyms

    S100A6; 2A9; 5B10; CABP; CACY; PRA; MLN 4; S100 calcium-binding protein A6 (calcyclin); calcyclin; growth factor-inducible protein 2A9; prolactin receptor-associated protein; protein S100-A6;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Chicken
  • Human
  • Mouse
  • Rabbit
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|S
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human S100A6-916H Recombinant Human S100A6, His-tagged E.coli His
Human S100A6-3101H Recombinant Human S100A6 protein E.coli Met1-Gly90
Human S100A6-2212H Recombinant Human S100A6 protein, His-tagged Insect Cells His Met1-Gly90
Human S100A6-1773H Recombinant Human S100A6 protein, His & S-tagged E.coli His/S Met1~Gly90 (Accession # P06703)
Human S100A6-690HCL Recombinant Human S100A6 cell lysate Insect Cell N/A
Human S100A6-228H Recombinant Human S100A6 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human S100A6-620H Recombinant Human S100A6 Protein E.coli N/A Met 1-Gly 90
Human S100A6-2140HFL Recombinant Full Length Human S100A6 Protein, C-Flag-tagged Mammalian cells Flag
Human S100A6-4913H Recombinant Human S100A6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human S100A6-1941H Recombinant Human S100A6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human S100A6-3462H Recombinant Human S100A6 protein, His-SUMO-tagged E.coli His-SUMO 1-90aa
Human S100A6-1941H-B Recombinant Human S100A6 Protein Pre-coupled Magnetic Beads HEK293
Human S100A6-6216H Recombinant Human S100A6 Protein (Met1-Gly90), His tagged E.coli His Met1-Gly90
Mouse S100A6-3100M Recombinant Mouse S100A6 protein(Met1-Lys89) E.coli N/A Met1-Lys89
Mouse S100a6-845M Recombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin) HEK293 N/A
Mouse S100a6-5106M Recombinant Mouse S100 calcium Binding Protein A6 (calcyclin), His-tagged Mouse His
Mouse S100a6-3552M Recombinant Mouse S100a6, His-tagged Mouse His
Mouse S100a6-7326M Recombinant Mouse S100a6 Protein, His-tagged E.coli His 1-89
Mouse S100a6-5670M Recombinant Mouse S100a6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse S100a6-43M Native Mouse S100A6 N/A
Rat S100a6-1774R Recombinant Rat S100a6 protein, His-tagged E.coli His Met1~Lys89 (Accession # P05964)
Rabbit S100A6-1775R Recombinant Rabbit S100A6 protein, His-tagged E.coli His Met1~Gly90 (Accession # P30801)
Rhesus Macaque S100A6-4063R Recombinant Rhesus monkey S100A6 Protein, His-tagged Mammalian Cell His
Rhesus Macaque S100A6-3880R Recombinant Rhesus Macaque S100A6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque S100A6-3880R-B Recombinant Rhesus Macaque S100A6 Protein Pre-coupled Magnetic Beads HEK293
Chicken S100A6-5724C Recombinant Chicken S100A6 Mammalian Cell His
S100a6-4566M Recombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin) Mouse N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

S100A6 involved in several pathways and played different roles in them. We selected most pathways S100A6 participated on our site, such as Gastric cancer network 2, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gastric cancer network 2CHTF18;S100A6;SNRPN;TOP2A;CEBPZ;BRIX1;PLAC8;ATAD2;RAD17
Prostaglandin Synthesis and RegulationANXA5;ANXA4;ANXA3;ANXA6;S100A10;CC10;S100A6;ANXA2

S100A6 has several biochemical functions, for example, S100 protein binding, calcium ion binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A6 itself. We selected most functions S100A6 had, and list some proteins which have the same functions with S100A6. You can find most of the proteins on our site.

Function Related Protein
S100 protein bindingFGF1;AHNAK;FGF1A;DDX1;S100A1;KCNK3;ANXA11;ATP2A2;S100B
calcium ion bindingPCDH2G16;PCDH2G29;MAN1B1;DGKB;MYL9B;EGFL8;MMP13A;DLC;NUCB1
calcium-dependent protein bindingCHP1;CHP;STMN2;CALM1;MBL2;ALG2;S100B;VPS37B;SLC9A1
ion transmembrane transporter activitySFXN5B;LASP1;SFXN2;SFXN4;S100A6;PLP2;TRPV2;SFXN5A;SFXN1
protein bindingC2orf50;EIF2A;SLC4A1A;NSFL1C;SORBS2;ATPAF1;DYRK4;PROL1;ZNF263
protein homodimerization activityCEBPE;PVRL2L;LRRFIP1;RIPK2;MAP3K10;NPM1;APOBEC3G;MAP3K5;RXRB
tropomyosin bindingTMOD2;PYCARD;TNNT2A;TNNT3;TNNT1;TMOD4;LMOD3;TMOD3;CALD1
zinc ion bindingZNFL1;UBR1;HLTF;ZDHHC3B;MARCH6;VPS11;RNF144AB;SIAH2L;BMP1B

S100A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A6.

KPNA2; PPID; FKBP4; PEX5; MDM2; S100B; TP53

Research Area

Related articles

Meghnani, V; Wagh, A; et al. The receptor for advanced glycation end products influences the expression of its S100 protein ligands in melanoma tumors. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 57:54-62(2014).
Jurewicz, E; Goral, A; et al. S100A6 is secreted from Wharton's jelly mesenchymal stem cells and interacts with integrin beta 1. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 55:298-303(2014).
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