Recombinant Mouse S100 calcium Binding Protein A6 (calcyclin), His-tagged

• Cat.No.: S100a6-5106M
• Product Overview: Recombinant mouseS100a6 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Species: Mouse
• Source: Mouse
• Tag: His
• Description: S100a6 belongs tothe S100 family. S100 family contains 2 EF-hand calcium-binding motifs. S100proteins regulate a number of cellular processes such as cell cycleprogressions and differentiation. S100a6 plays a role in the reorganizationof the actin cytoskeleton and in cell mobility. This is a specific target ofS-100B protein in vivo. The binding of S100a6 to S100B is stabilized byS100B-bound calcium and zinc. It associates with both Annexin XI and CacyBP(Calcyclin-binding protein). It functions to activate several processes alongthe calcium signal transduction pathway including the regulation of cellgrowth, proliferation, secretion and exocytosis.
• Concentration: 0.5 mg/ml
• Form: Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 30% glyceroland 100mM NaCl.
• Purity: > 95% by SDS -PAGE
• Sequence: 1-89 amino acids:MGSSHHHHHH SSGLVPRGSH MACPLDQAIG LLVAIFHKYS GKEGDKHTLS KKELKELIQK ELTIGSKLQDAEIARLMDDL DRNKDQEVNF QEYVAFLGAL ALIYNEALK
• Molecular Mass: 12.2 kDa(109aa), confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: S100a6
• Pathways: Prostaglandin Synthesis and Regulation

Gene Information

• Gene Name: S100a6S100 calcium binding protein A6 (calcyclin) [ Mus musculus ]
• Synonyms: S100a6; S100 calcium binding protein A6 (calcyclin); 2A9; PRA;5B10; Cacy; CALCYCLIN; protein S100-A6; S100 calcium-binding protein A6;prolactin receptor-associated protein; calcium binding protein A6 (calcyclin); Protein S100-A6; Calcyclin; Prolactin receptor-associated protein; S100calcium-binding protein A6
• Gene ID: 20200
• mRNA Refseq: NM_011313
• Protein Refseq: NP_035443
• UniProt ID: P14069
• Chromosome Location: 39.35 cM
• Function: S100 beta binding; calciumion binding; calcium-dependent protein binding; ion transmembrane transporteractivity; metal ion binding; protein binding; protein homodimerization activity;tropomyosin binding; zinc ion binding