Recombinant Human Transforming Growth Factor Beta 2

Cat.No. : TGFB2-438H
Product Overview : Recombinant Human Transforming Growth Factor Beta 2 is expressed inE. coli.
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Species : Human
Source : E.coli
Tag : Non
Description : Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This cytokine is produced in a human cell expression system with serum-free, chemically defined media.
Purity : >98% pure as demonstrated by SDS-gel electrophoresis and reverse phase HPLC.
Molecular Weight : 35.8 kDa.
Presentation : Solution containing 50 mM TRIS, 100 mM NaCl, 1% BSA, 0.02% Sodium Azide, pH 7.4.
Biological Activity : Annexin V exhibits anti-phospholipase activity and binds to phosphatidylserine (PS).
Application : FITC labelling allows simple direct detection of PS by FACS analysis. Counterstaining by propidium iodide allows the discrimination of apoptotic cells.
Storage : Stable at 2°-8°C as indicated on the label. Do not freeze!
Gene Name TGFB2 transforming growth factor, beta 2 [ Homo sapiens ]
Synonyms
TGFB2; Transforming growth factor beta 2; MGC116892; TGF-beta2; Transforming growth factor beta-2; TGF-beta-2; Glioblastoma-derived T-cell suppressor factor; G-TSF; BSC-1 cell growth inhibitor; Polyergin; Cetermin
Gene ID 7042
mRNA Refseq NM_001135599
Protein Refseq NP_001129071
MIM 190220
UniProt ID P61812
Chromosome Location 1q41
Pathway Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Renal cell carcinoma; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway
Function beta-amyloid binding; cytokine activity; growth factor activity; protein heterodimerization activity; protein homodimerization activity; receptor signaling protein serine/threonine kinase activity; type II transforming growth factor beta receptor binding

Wnt-Induced Stabilization of KDM4C Is Required for Wnt/β-Catenin Target Gene Expression and Glioblastoma Tumorigenesis

Journal: Cancer Research    Data: 2019/12/30

Authors: Yaohui Chen, Runping Fang, Suyun Huang

Article Snippet:Empty anti-Flag agarose beads were used as a control.Empty anti-Flag agarose beads were used as a control.. The in vitro ubiquitination assay was performed by incubating KDM4C or control agarose beads at 37°C for 1 hour with E1 ubiquitinactivating enzyme UBE1, E2-conjugating enzyme UbcH5c, HA-ubiquitin, and adenosine triphosphate (all from Boston Biochem) in the presence or absence of recombinant β-TrCP protein (Creative BioMart, Research. on January 1, 2020.. ? 2019 American Association for Cancercancerres.aacrjournals.org Downloaded from 7 BTRC-2545M).? 2019 American Association for Cancercancerres.aacrjournals.org Downloaded from 7 BTRC-2545M).

Not For Human Consumption!

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