VIM

Official Full Name

vimentin
Overview

Vimentin is 57 kDa intermediate filament proteins in mesenchymal cells. It is attached to the nucleus, endoplasmic reticulum and mitochondria either laterally or terminally. Vimentin is important in the differential diagnosis of undifferentiated neoplasm.
Synonyms

VIM; vimentin; HEL113; CTRCT30; epididymis luminal protein 113; FLJ36605;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads
GMP Proteins
Native Proteins

Species

Bovine
Chicken
Cynomolgus Monkey
Human
Mouse
Rat
Zebrafish

Source

Bovine Lens
E.coli
HEK293
HEK293T
Human
Insect Cell
Insect Cells
Mammalian Cell
Mammalian cells
Yeast

Tag

C
His
Strep
Flag
GST
Fc
Avi
Myc
T7
DDK
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	VIM-250H	Recombinant Human VIM protein, His-tagged	E.coli	His		Inquiry
Human	VIM-16H	Recombinant Human VIM Full Length protein, His-tagged	Insect Cell	His	Met1-Glu466	Inquiry
Human	VIM-185H	Recombinant human VIM	E.coli	Non		Inquiry
Human	VIM-52H	Recombinant Human Vimentin	E.coli	His	1-466	Inquiry
Human	VIM-30158TH	Recombinant Human VIM, His-tagged	E.coli	His		Inquiry
Human	VIM-233H	Recombinant Human VIM protein	E.coli	Non	465	Inquiry
Human	VIM-4893H	Recombinant Human Vimentin, His-tagged	E.coli	His		Inquiry
Human	VIM-4679H	Recombinant Human Vimentin, GST-tagged	Human	GST		Inquiry
Human	VIM-203H	Recombinant Human VIM protein, T7/His-tagged	E.coli	His&T7		Inquiry
Human	VIM-1907HCL	Recombinant Human VIM cell lysate		Non		Inquiry
Human	VIM-2340H-B	Recombinant Human VIM Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	VIM-571H	Recombinant Human VIM Protein, His-tagged	E.coli	His	Glu286-Glu408	Inquiry
Human	VIM-368H	Recombinant Human VIM Protein, MYC/DDK-tagged	HEK293	Myc&DDK		Inquiry
Human	VIM-211HG	GMP Recombinant Human VIM protein	HEK293		DNA sequence encoding Human Vimentin(NP_003371.2) was expressed with His tag at the C-terminal.	Inquiry
Human	VIM-001H	Active Recombinant Human VIM Protein, His-tagged	E.coli	His	Ser2-Glu466	Inquiry
Human	VIM-5546H	Recombinant Human VIM protein, His-tagged	Yeast	His	2-466aa	Inquiry
Human	VIM-17HFL	Recombinant Full Length Human VIM Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	VIM-4023H	Recombinant Human VIM Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Human	VIM-3160H	Recombinant Human VIM protein, His-tagged	E.coli	His	1-466 aa	$319 / 25μg
Human	VIM-2340H	Recombinant Human VIM Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Human	VIM-17H	Recombinant Human VIM Full Length protein, His&Strep-tagged	Insect Cells	C-His-Strep	Met1-Glu466	Inquiry
Mouse	VIM-18018M	Recombinant Mouse VIM Protein	Mammalian Cell	His		Inquiry
Mouse	Vim-251M	Recombinant Mouse Vim protein, His-tagged	E.coli	His	Ser2~Glu466	Inquiry
Mouse	Vim-3755M	Recombinant Mouse Vim protein, His&Myc-tagged	E.coli	His&Myc	2-466aa	Inquiry
Mouse	Vim-5931M	Recombinant Mouse Vim protein, His&Myc-tagged	HEK293	His&Myc	2-466aa	Inquiry
Mouse	VIM-10017M	Recombinant Mouse VIM Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	Vim-6923M	Recombinant Mouse Vim Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Mouse	VIM-10017M-B	Recombinant Mouse VIM Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	VIM-6522R	Recombinant Rat VIM Protein	Mammalian Cell	His		Inquiry
Rat	Vim-252R	Recombinant Rat Vim protein, His-tagged	E.coli	His		Inquiry
Rat	VIM-6178R	Recombinant Rat VIM Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rat	VIM-6178R-B	Recombinant Rat VIM Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Bovine	WIM-5415B	Native Bovine Vimentin		Non		Inquiry
Bovine	VIM-186B	Native Bovine Vimentin	Bovine Lens	Non		Inquiry
Cynomolgus Monkey	VIM-1086C	Recombinant Cynomolgus VIM Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	VIM-829C-B	Recombinant Cynomolgus Monkey VIM Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Cynomolgus Monkey	VIM-829C	Recombinant Cynomolgus Monkey VIM Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Zebrafish	VIM-9376Z	Recombinant Zebrafish VIM	Mammalian Cell	His		Inquiry
Chicken	VIM-3504C	Recombinant Chicken VIM	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

VIM involved in several pathways and played different roles in them. We selected most pathways VIM participated on our site, such as Epstein-Barr virus infection, MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with VIM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Epstein-Barr virus infection	PSMC1;EP300;EIF2AK1;CDK1;GTF2E2;SKP2;PRKACA;PIK3CA;NFKBIB
MicroRNAs in cancer	STMN1;ITGB3;PRKCA;MET;TGFB2;APC2;RHOA;CCNE2;ZFPM2

VIM has several biochemical functions, for example, double-stranded RNA binding, glycoprotein binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VIM itself. We selected most functions VIM had, and list some proteins which have the same functions with VIM. You can find most of the proteins on our site.

Function	Related Protein
double-stranded RNA binding	DGCR8;LSM14A;MTDH;RNASEN;OAS1A;AGO1;RFTN1;STAU2;OAS2
glycoprotein binding	BMPR1A;SERPINA1D;SELP;LDLR;CDH1;AZGP1;RASA1;FBXO17;PTBP3
identical protein binding	REG3B;MRAP2;CEP72;IFI16;HOOK2;GRIN3A;MMP9;PRC1;MAP3K13
keratin filament binding	KRT14;SIRT1;VIM
protein C-terminus binding	PEX10;CDK7;MYO1C;C11orf60;BAIAP2;VGLL2;NPAT;VGLL1;YWHAB
protein binding	USP44;NFKBIL1;RAB7A;TGS1;GBP1;KLHL35;PKP1;RRAGD;ARHGAP4
scaffold protein binding	CAV2;NOS1;KCNQ1;MDM2;VIM;CHUK;KRT15;IKBKB;DSP
structural constituent of cytoskeleton	TUBG1;TUBA1B;VIM;ACTG1;TUBA8;TNNT2A;ACTR2;ARPC4;PLS1
structural constituent of eye lens	CRYBB1;CRYGA;LIM2;CRYBA4;CRYBB2;ASL1;ATXN1;CRYGF;VIM

VIM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VIM here. Most of them are supplied by our site. Hope this information will be useful for your research of VIM.

KAT7; NOD2; AKT1

Research Area

Mesenchymal Cells and EMT

Myogenesis Markers

Glial Lineage Markers

Neural Crest Cell Markers

Neural Progenitor Cell Markers

Neural Stem Cell Markers

Mesenchymal Stem Cell Markers

Intermediate Filaments

Mesodermal Lineage Markers

Fenoglio, C; Albicini, F; et al. Renal Fibrogenesis and Platinum Compounds in a Rat Model: A Novel Pt (II) Complex vs. Cisplatin. ANTICANCER RESEARCH 35:739-751(2015).

Ripoll, VM; Lambrianides, A; et al. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. BLOOD 124:3808-3816(2014).