Cat.No. : |
Kit-1886
Optional Service: Optional requirements on this protein
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Product Overview : |
TNKS2 catalyzes the NAD-dependent addition of poly (ADP-ribose) to the substrate proteins. |
Size : |
96 reactions |
Description : |
The TNKS2 Histone Ribosylation Assay Kit (Biotin-labeled NAD+) is designed to measure Tankyrase 2 (TNKS2) activity for screening and profiling applications. The key to the TNKS2 Histone Ribosylation Assay is the biotinylated NAD+ substrate. With this kit, only three simple steps are required for TNKS2 reactions. First, histone proteins are coated on a 96-well plate. Next, the biotinylated NAD+ substrate is incubated with an assay buffer that contains the TNKS2 enzyme. Finally, the plate is treated with streptavidin-HRP followed by addition of the HRP substrate to produce chemiluminescence that can be measured using a chemiluminescence reader. |
Applications : |
Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
Storage : |
12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |