TNKS2 Histone Ribosylation Colorometric Assay Kit Kit-1888

TNKS2 Histone Ribosylation Colorometric Assay Kit

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TNKS2 Histone Ribosylation Colorometric Assay Kit

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Cat.No. : Kit-1888
Size : 96 reactions
Description : The TNKS2 Histone Ribosylation Colorimetric Assay Kit is designed to measure Tankyrase 2 (TNKS2) activity for screening and profiling applications. TNKS2 catalyzes the NAD-dependent addition of poly (ADP-ribose) to the substrate proteins. The key to the TNKS2 Histone Ribosylation Assay is the biotinylated NAD+ substrate. With this kit, only three simple steps are required for TNKS2 reactions. First, histone proteins are coated on a 96-well plate. Next, the biotinylated NAD+ substrate is incubated with an assay buffer that contains the TNKS2 enzyme. Finally, the plate is treated with streptavidin-HRP followed by addition of the colorimetric HRP substrate to produce color that can then be measured using a UV/Vis spectrophotometer microplate reader.
Applications : Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Storage : Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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