Active Recombinant Human CD28 protein, Biotin-labelled
Cat.No. : | CD28-32H |
Product Overview : | Human CD28-muIg fusion protein was Protein A purified from (low FBS containing) tissue culture supernatant of CHO transfectants, and reacted with NHS-Biotin. Unconjugated Biotin was removed from conjugate by diafiltration. A soluble fusion protein consisting of the extracellular (134aa) domain of human CD28 fused to murine IgG2a Fc (233aa). |
Availability | July 14, 2025 |
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Species : | Human |
Source : | CHO |
Tag : | Non |
Description : | Human CD28 is an important costimulatory molecule found on all CD4+ T cells and on about half of the CD8+T cells. T cell activities attributed to CD28 include, prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNAs and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, identified as CD80 (B7-1) and CD86 (B7-2), are immunoglobulin superfamily monomeric transmembrane glycoproteins of 60 kd and 80 kd, respectively. |
Bio-activity : | CD28-muIg/Biotin activity was assessed in EIA utilizing GAM-captured Recombinant CD80-muIg, and Streptavidin/HRP as a detector. In this format, the fusion protein was detectable at 100 ng/ml. |
Notes : | Research use only. Not for use in Diagnostic procedures. |
Stability : | Product should retain activity for at least 12 months after shipping date when stored as recommended. |
Storage : | Store at 2 - 5 centigrade. Freeze/Thawing is not recommended. |
Concentration : | 0.5 mg/mL |
Storage Buffer : | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
Gene Name | CD28 |
Official Symbol | CD28 CD28 molecule [ Homo sapiens (human) ] |
Synonyms | CD28; CD28 molecule; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen |
Gene ID | 940 |
mRNA Refseq | NM_006139 |
Protein Refseq | NP_006130 |
MIM | 186760 |
UniProt ID | P10747 |
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Not For Human Consumption!
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