CD28 Protein

CD28

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CD28

Official Full Name CD28 CD28 molecule
Synonyms CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290;
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Felis catus (Cat) (Felis silvestris catus)
    • Gallus gallus (Chicken)
    • Homo sapiens (Human)
    • Human
    • Human / Cynomolgus / Rhesus Monkey
    • Human/Cynomolgus
    • Human/Cynomolgus/Rhesus macaque
    • Monkey
    • Mouse
    • Mus musculus (Mouse)
    • Oryctolagus cuniculus (Rabbit)
    • Rat
    • Rattus norvegicus (Rat)
    • Rhesus Macaque
    • Source :
    • CHO
    • CHO cells
    • E.coli
    • E.coli expression system
    • HEK293
    • HEK293F
    • Human Cell
    • Human Cells
    • In Vitro Cell Free System
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Avi
    • Fc
    • DDK
    • His
    • Fc/Avi
    • Fc/His
    • Fc-His(C-ter)
    • GST
    • hFc
    • HIgG/His
    • Flag
    • StrepII
    • His-Avi
    • human
    • IgG1
    • LEVLFQ
    • Mouse
    • IgG2a
    • N/A
    • N-His
    • N-His&SUMO
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD28-212H Active Recombinant Human CD28, MIgG2a Fc-tagged CHO Fc
    Human CD28-378H Active Recombinant Human CD28, HIgG1 Fc-tagged CHO Fc
    Human CD28-3908H Active Recombinant Human CD28 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human CD28-566H Active Recombinant Human CD28, Fc-tagged, Biotinylated Human Cell Fc
    Mouse CD28-232M Active Recombinant Mouse CD28, MIgG2a Fc-tagged CHO Fc
    Human CD28-01H Active Recombinant Human CD28 protein, hIgG-His-tagged Insect Cell HIgG/His
    Human CD28-051H Active Recombinant Human CD28 protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi
    Human CD28-32H Recombinant Human CD28 protein, Biotin-labelled CHO N/A
    Human CD28-0772H Recombinant Human CD28 Protein Wheat Germ N/A
    Human CD28-0773H Recombinant Human CD28 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
    Human CD28-0774H Recombinant Human CD28 Protein, GST-Tagged Wheat Germ GST
    Human CD28-142H Recombinant Human CD28, Fc-tagged CHO Fc
    Human CD28-1593H Recombinant Human CD28 Molecule Mammalian cells N/A
    Human CD28-181H Recombinant Human CD28 Protein, DDK/His-tagged HEK293 DDK/His
    Human CD28-182H Recombinant Human CD28 Protein, Fc-tagged HEK293 Fc
    Human CD28-321H Recombinant Human CD28 Protein HEK293 N/A
    Human CD28-3909H Recombinant Human CD28, Fc tagged Human Cell Fc
    Human CD28-3910H Recombinant Human CD28, His tagged Human Cell His
    Mouse Cd28-1712M Recombinant Mouse CD28 Antigen, Fc-His Mammalian cells Fc/His
    Mouse Cd28-4008M Recombinant Mouse Cd28 protein, His-tagged HEK293 His
    Mouse CD28-640M Recombinant Mouse CD28, Fc-His tagged Human Cell Fc/His
    Mouse Cd28-661M Recombinant Mouse Cd28 protein, His & GST-tagged E.coli His/GST
    Rat CD28-1099R Recombinant Rat CD28 Protein, Fc-tagged HEK293 Fc
    Rat CD28-1100R Recombinant Rat CD28 Protein, His-tagged HEK293 His
    Rat CD28-1244R Recombinant Rat CD28 Protein Mammalian Cell His
    Cynomolgus Monkey CD28-1204C Recombinant Cynomolgus CD28 Protein, Fc-tagged HEK293 Fc
    Cynomolgus Monkey CD28-387C Recombinant Cynomolgus CD28 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CD28-733R Recombinant Rhesus monkey CD28 Protein, His-tagged Mammalian Cell His
    Chicken CD28-6863C Recombinant Chicken CD28 Mammalian Cell His
    Human CD28-2013HCL Recombinant Human CD28 cell lysate Human Cell N/A
    Mouse CD28-2002MCL Recombinant Mouse CD28 cell lysate Human Cell N/A
    Rat CD28-1099RAF488 Recombinant Rat CD28 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Rat CD28-1099RAF555 Recombinant Rat CD28 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Rat CD28-1099RAF647 Recombinant Rat CD28 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Rat CD28-1099RF Recombinant Rat CD28 Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Rat CD28-1100RAF488 Recombinant Rat CD28 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Rat CD28-1100RAF555 Recombinant Rat CD28 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Rat CD28-1100RAF647 Recombinant Rat CD28 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Rat CD28-1100RF Recombinant Rat CD28 Protein, His-tagged, FITC conjugated HEK293 His
    Monkey CD28-1204CAF488 Recombinant Monkey CD28 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Monkey CD28-1204CAF555 Recombinant Monkey CD28 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Monkey CD28-1204CAF647 Recombinant Monkey CD28 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Monkey CD28-1204CF Recombinant Monkey CD28 Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Human CD28-151H Recombinant Human CD28 Protein, His-tagged Human Cells His
    Mouse Cd28-28M Recombinant Mouse CD28 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter)
    Human CD28-3092HF Recombinant Full Length Human CD28 Protein In Vitro Cell Free System
    Human CD28-3095HF Recombinant Full Length Human CD28 Protein, GST-tagged In Vitro Cell Free System GST
    Human CD28-321HAF488 Recombinant Human CD28 Protein, Alexa Fluor 488 conjugated HEK293 LEVLFQ
    Human CD28-321HAF555 Recombinant Human CD28 Protein, Alexa Fluor 555 conjugated HEK293 LEVLFQ
    Human CD28-321HAF647 Recombinant Human CD28 Protein, Alexa Fluor 647 conjugated HEK293 LEVLFQ
    Human CD28-321HF Recombinant Human CD28 Protein, FITC conjugated HEK293 LEVLFQ
    Human/Cynomolgus CD28-339H Recombinant Human/Cynomolgus CD28(Asn19-Pro152) Protein, N-6*His-tagged HEK293 His
    Human CD28-3909HAF488 Recombinant Human CD28 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Human CD28-3909HAF555 Recombinant Human CD28 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Human CD28-3909HAF647 Recombinant Human CD28 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Human CD28-3909HF Recombinant Human CD28 Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Mouse Cd28-4008MAF488 Recombinant Mouse Cd28 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Mouse Cd28-4008MAF555 Recombinant Mouse Cd28 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Mouse Cd28-4008MAF647 Recombinant Mouse Cd28 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Mouse Cd28-4008MF Recombinant Mouse Cd28 Protein, His-tagged, FITC conjugated HEK293 His
    Human CD28-4995H Recombinant Human CD28 protein, hFc-tagged HEK293 hFc
    Mouse CD28-640MAF488 Recombinant Mouse CD28 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His
    Mouse CD28-640MAF555 Recombinant Mouse CD28 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His
    Mouse CD28-640MAF647 Recombinant Mouse CD28 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His
    Mouse CD28-640MF Recombinant Mouse CD28 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His
    Mouse Cd28-666M Recombinant Mouse Cd28 Protein, His-tagged E.coli N-His
    Human CD28-667H Recombinant Human CD28 Protein, His-tagged HEK293F N-His
    Human CD28-668H Recombinant Human CD28 Protein, His&SUMO-tagged HEK293F N-His&SUMO
    Rat Cd28-669R Recombinant Rat Cd28 Protein, His-tagged E.coli N-His
    Gallus gallus (Chicken) RFL10568GF Recombinant Full Length Chicken T-Cell-Specific Surface Glycoprotein Cd28 Homolog(Cd28) Protein, His-Tagged E.coli expression system His
    Felis catus (Cat) (Felis silvestris catus) RFL13001FF Recombinant Full Length Cat T-Cell-Specific Surface Glycoprotein Cd28(Cd28) Protein, His-Tagged E.coli expression system His
    Rattus norvegicus (Rat) RFL17688RF Recombinant Full Length Rat T-Cell-Specific Surface Glycoprotein Cd28(Cd28) Protein, His-Tagged E.coli expression system His
    Homo sapiens (Human) RFL24979HF Recombinant Full Length Human T-Cell-Specific Surface Glycoprotein Cd28(Cd28) Protein, His-Tagged E.coli expression system His
    Oryctolagus cuniculus (Rabbit) RFL29096OF Recombinant Full Length Rabbit T-Cell-Specific Surface Glycoprotein Cd28(Cd28) Protein, His-Tagged E.coli expression system His
    Mus musculus (Mouse) RFL5884MF Recombinant Full Length Mouse T-Cell-Specific Surface Glycoprotein Cd28(Cd28) Protein, His-Tagged E.coli expression system His
    Human CD28-332HG GMP Recombinant Human CD28 protein, Fc-tagged HEK293 Fc
    Human CD28-747H Recombinant Human CD28 protein, His-Avi-tagged HEK293 His-Avi
    Human CD28-747HB Recombinant Human CD28 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Mouse CD28-339M Recombinant Mouse CD28 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human/Cynomolgus/Rhesus macaque CD28-336H Recombinant Human/Cynomolgus/Rhesus macaque CD28 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Human/Cynomolgus/Rhesus macaque CD28-337H Recombinant Human/Cynomolgus/Rhesus macaque CD28 protein, His-tagged HEK293 His
    Human / Cynomolgus / Rhesus Monkey CD28-338H Recombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human/Cynomolgus/Rhesus macaque CD28-562H Recombinant Human/Cynomolgus/Rhesus macaque CD28 protein, Fc-tagged (HPLC-verified) HEK293 human/IgG1/Fc
    Kit-1705 CD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit N/A

    CD28 involved in several pathways and played different roles in them. We selected most pathways CD28 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) CNTNAP2; F11R; CD8B1; CLDN15LB; CLDN14; CLDN23; MHC2DAB; CD58; CADM1; F11R.1
    T cell receptor signaling pathway MAP2K2; PIK3R1; CD8B1; IL4; DEF6A; PAK3; CD28; IKBKG; CBLB; PIK3CB
    Intestinal i HLA-DRB1; HLA-DRA; PIGR; BMA2; CCL28; Icosl; IL-15RA; CD28; ITGA4; AICDA
    ne network for IgA production LTBR; CD40; ITGB7; CCR9A; HLA-DQA1; TNFSF13; HLA-DRB3; MHC2DAB; CXCR4; MAP3K14
    Type I diabetes mellitus HLA-DRB3; HLA-DMB; HLA-DRB4; GZMB; HLA-DOB; INS2; ICA1; LTA; HLA-DOA; FAS
    Measles TLR9; IFNA16; PIK3R5; IFNA21; OAS2; CD28; EIF2AK3; PIK3CA; FCGR2B; CCNE1
    Autoi HLA-DQA2; HLA-DOA; CD28; IFNA4; CD80; IFNA10; IFNA5; HLA-B; HLA-DPB1; HLA-A
    ne thyroid disease GZMB; CD86; HLA-DMA; IFNA17; TSHB; HLA-G; HLA-A; IFNA16; IFNA2; Il2
    Systemic lupus erythematosus HIST1H3I; C8B; HIST1H2AF; HIST1H2AG; HIST1H2AO; H2AFB2; HLA-DRB4; HIST1H3D; HIST2H4A; ACTN1
    Rheumatoid arthritis MMP3; ATP6V1D; FLT1; IL23; ATP6V1E2; HLA-DRB4; ATP6V1C2; ATP6V1B1; Il23a; ATP6V1F
    Allograft rejection HLA-DPA1; IL12A; H2-AB1; HLA-DMB; GZMB; CD86; CD40LG; IL5; IL4; Fasl
    Graft-versus-host disease HLA-DOA; IFNG; IL6; HLA-DRB3; KIR2DL3; IL1A; HLA-DMA; KIR3DL2; H2-AB1; TNF
    Viral myocarditis CYCS; CASP8; FYN; ITGB2; CXADR; EIF4G3; HLA-G; HLA-DMB; HLA-F; SGCB

    CD28 has several biochemical functions, for example, SH3/SH2 adaptor activity, coreceptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD28 itself. We selected most functions CD28 had, and list some proteins which have the same functions with CD28. You can find most of the proteins on our site.

    Function Related Protein
    SH3/SH2 adaptor activity FCRL2; PTPN11; STAM; CD28; SH3BP2; SHB; STAP1; GRB14; TOB1; RUSC1
    coreceptor activity ZP2; CCR8; HFE2; ACKR3B; LRP5; CD28; CXCR7; LY96; CD80; PVRL1
    identical protein binding MCPH1; BLOC1S6; RELA; TTN; SIAH1; LYZ1; CLDN3; POU3F2; RAF1; DAPK3
    protease binding Casp3; RFFL; XBP1; CSTA; RYR1; SERPINA1; TNFRSF10A; MBP; SERPINB4; SERPINC1
    protein binding USP20; HEMGN; CCDC13; PXMP4; MAGEA6; OSR2; UBQLN4; C21orf56; WIF1; MAB21L3

    CD28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD28 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD28.

    PIK3R1; GRAP2; CD80; PIK3R1; Pik3r1; GRB2; PRKCQ

    Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
    Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).

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