| Official Full Name | CD28 CD28 molecule |
| Synonyms | CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290; |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
cd28 involved in several pathways and played different roles in them. We selected most pathways cd28 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | MAG; CD40; ITGB7; NEO1; NCAM1B; CDH5; CADM1A; CLDN15A; JAM3B; GLG1 |
| T cell receptor signaling pathway | TEC; PTPN6; AKT2; MAPK11; RHOA; CD4; AKT1; BCL10; VAV3; PPP3CC |
| Intestinal i | MHC2DAB; HLA-DOB; CD86; HLA-DRB4; HLA-DQA2; MHC2DCB; TGFB1A; CXCR4; HLA-DRB5; CXCL12 |
| ne network for IgA production | IL-15RA; CD80; MHC2DAB; BLB1; HLA-DPA1; CCR9A; MHC2A; CD40; AICDA; HLA-DRB3 |
| Type I diabetes mellitus | PTPRN; HLA-DQA2; HLA-DMB; GZMB; HLA-DPB1; HLA-DRB1; Il2; CPE; HLA-DOA; PRF1 |
| Measles | TNFRSF10D; IFNA2; MAVS; CD209B; IFNGR1; STAT5B; CD3E; CD3D; PIK3R1; TNFRSF10C; NFKB1 |
| Autoi | TPO; HLA-DMA; IFNA6; Il2; CD40LG; IFNA4; CD40; HLA-DPA1; PRF1; HLA-E |
| ne thyroid disease | TPO; CD86; TSHR; HLA-DMB; HLA-DRB1; HLA-G; IL4; PRF1; H2-Q10; FAS |
| Systemic lupus erythematosus | HIST1H4G; C4A; GM14478; HLA-DRA; HIST1H2AA; GM6026; HIST1H4K; HIST2H2AC; HIST1H2AF; HIST1H3C |
| Rheumatoid arthritis | Il23a; HLA-DRB4; IL1A; TGFB3; IL-8; ATP6V1G1; ATP6V1H; CCL2; HLA-DQA1; CD80 |
| Allograft rejection | GZMB; CD40LG; HLA-DRA; TNF; PRF1; HLA-DRB3; HLA-F; HLA-G; HLA-DQA2; IL4 |
| Graft-versus-host disease | KIR3DL2; HLA-A; KIR3DL1; HLA-DRB5; CD28; GZMB; H2-AB1; HLA-DRA; H2-AA; KIR2DL3 |
| Viral myocarditis | EIF4G2; ITGB2; HLA-A; CD40LG; HLA-DPA1; ACTG1; CASP8; HLA-C; ITGAL; CCND1 |
cd28 has several biochemical functions, for example, SH3/SH2 adaptor activity, coreceptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd28 itself. We selected most functions cd28 had, and list some proteins which have the same functions with cd28. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH3/SH2 adaptor activity | CHN1; SH2D3A; GRAP; KHDRBS1; SH3BP2; CRK; NCK2; ARHGAP1; GRB2; CD28 |
| coreceptor activity | CD80; CD86; CXCR7B; RGMD; CD8A; PVRL2; TGFBR3; RAMP2; TMIGD2; CCR8 |
| identical protein binding | NCAM1; TRIM21; DAPK3; PARK2; INS; APLP1; PCM1; MAP1S; SEPT7; IGF2R |
| protease binding | HSPA6; TP53; LRP1; CSTA; CD70; SERPINE1; BRCA2; SERPINA5; INS; ECM1 |
| protein binding | MAPK3; SFRP1; GRM2; RUSC1; EHD1; RAB11FIP3; ADAMTS10; RNF24; MARCH2; SEMA4D |
cd28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd28 here. Most of them are supplied by our site. Hope this information will be useful for your research of cd28.
PIK3R1; GRAP2; CD80; PIK3R1; Pik3r1; GRB2; PRKCQ
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