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Official Full Name CD28 CD28 molecule
Synonyms CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290;
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Human / Cynomolgus / Rhesus Monkey
    • Human/Cynomolgus/Rhesus macaque
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NSO
    • Wheat Germ
    • Tag :
    • Avi
    • Fc
    • DDK
    • His
    • GST
    • Flag
    • StrepII
    • His-Avi
    • human
    • IgG1
    • Mouse
    • IgG2a
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD28-32H Recombinant Human CD28 protein, Biotin-labelled CHO N/A
    Human CD28-332HG GMP Recombinant Human CD28 protein, Fc-tagged HEK293 Fc
    Human/Cynomolgus/Rhesus macaque CD28-336H Recombinant Human/Cynomolgus/Rhesus macaque CD28 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Human/Cynomolgus/Rhesus macaque CD28-337H Recombinant Human/Cynomolgus/Rhesus macaque CD28 protein, His-tagged HEK293 His
    Human / Cynomolgus / Rhesus Monkey CD28-338H Recombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Mouse CD28-339M Recombinant Mouse CD28 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human/Cynomolgus/Rhesus macaque CD28-562H Recombinant Human/Cynomolgus/Rhesus macaque CD28 protein, Fc-tagged (HPLC-verified) HEK293 human/IgG1/Fc
    Human CD28-747H Recombinant Human CD28 protein, His-Avi-tagged HEK293 His-Avi
    Human CD28-747HB Recombinant Human CD28 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Human CD28-0772H Recombinant Human CD28 Protein Wheat Germ N/A
    Human CD28-0773H Recombinant Human CD28 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
    Human CD28-0774H Recombinant Human CD28 Protein, GST-Tagged Wheat Germ GST
    Human CD28-142H Recombinant Human CD28, Fc-tagged CHO Fc
    Human CD28-1593H Recombinant Human CD28 Molecule NSO N/A
    Human CD28-181H Recombinant Human CD28 Protein, DDK/His-tagged HEK293 DDK/His
    Human CD28-182H Recombinant Human CD28 Protein, Fc-tagged HEK293 Fc
    Human CD28-2013HCL Recombinant Human CD28 cell lysate Human Cell N/A
    Human CD28-212H Recombinant Human CD28, MIgG2a Fc-tagged CHO Fc
    Human CD28-321H Recombinant Human CD28 Protein HEK293 N/A
    Human CD28-378H Recombinant Human CD28, HIgG1 Fc-tagged CHO Fc
    Human CD28-3908H Recombinant Human CD28 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human CD28-3909H Recombinant Human CD28, Fc tagged Human Cell Fc
    Human CD28-3910H Recombinant Human CD28, His tagged Human Cell His
    Human CD28-566H Recombinant Human CD28, Fc-tagged, Biotinylated Human Cell Fc
    Mouse Cd28-1712M Recombinant Mouse CD28 Antigen, Fc-His NSO Fc/His
    Mouse CD28-2002MCL Recombinant Mouse CD28 cell lysate Human Cell N/A
    Mouse CD28-232M Recombinant Mouse CD28, MIgG2a Fc-tagged CHO Fc
    Mouse Cd28-4008M Recombinant Mouse Cd28 protein, His-tagged HEK293 His
    Mouse CD28-640M Recombinant Mouse CD28, Fc-His tagged Human Cell Fc/His
    Mouse Cd28-661M Recombinant Mouse Cd28 protein, His & GST-tagged E.coli His/GST
    Rat CD28-1099R Recombinant Rat CD28 Protein, Fc-tagged HEK293 Fc
    Rat CD28-1100R Recombinant Rat CD28 Protein, His-tagged HEK293 His
    Rat CD28-1244R Recombinant Rat CD28 Protein Mammalian Cell His
    Cynomolgus Monkey CD28-1204C Recombinant Cynomolgus CD28 Protein, Fc-tagged HEK293 Fc
    Cynomolgus Monkey CD28-387C Recombinant Cynomolgus CD28 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CD28-733R Recombinant Rhesus monkey CD28 Protein, His-tagged Mammalian Cell His
    Chicken CD28-6863C Recombinant Chicken CD28 Mammalian Cell His
    Kit-1705 CD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit N/A

    cd28 involved in several pathways and played different roles in them. We selected most pathways cd28 participated on our site, such as Cell adhesion molecules (CAMs), T cell receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) MAG; CD40; ITGB7; NEO1; NCAM1B; CDH5; CADM1A; CLDN15A; JAM3B; GLG1
    T cell receptor signaling pathway TEC; PTPN6; AKT2; MAPK11; RHOA; CD4; AKT1; BCL10; VAV3; PPP3CC
    ne network for IgA production IL-15RA; CD80; MHC2DAB; BLB1; HLA-DPA1; CCR9A; MHC2A; CD40; AICDA; HLA-DRB3
    Type I diabetes mellitus PTPRN; HLA-DQA2; HLA-DMB; GZMB; HLA-DPB1; HLA-DRB1; Il2; CPE; HLA-DOA; PRF1
    Autoi TPO; HLA-DMA; IFNA6; Il2; CD40LG; IFNA4; CD40; HLA-DPA1; PRF1; HLA-E
    ne thyroid disease TPO; CD86; TSHR; HLA-DMB; HLA-DRB1; HLA-G; IL4; PRF1; H2-Q10; FAS
    Systemic lupus erythematosus HIST1H4G; C4A; GM14478; HLA-DRA; HIST1H2AA; GM6026; HIST1H4K; HIST2H2AC; HIST1H2AF; HIST1H3C
    Rheumatoid arthritis Il23a; HLA-DRB4; IL1A; TGFB3; IL-8; ATP6V1G1; ATP6V1H; CCL2; HLA-DQA1; CD80
    Allograft rejection GZMB; CD40LG; HLA-DRA; TNF; PRF1; HLA-DRB3; HLA-F; HLA-G; HLA-DQA2; IL4
    Graft-versus-host disease KIR3DL2; HLA-A; KIR3DL1; HLA-DRB5; CD28; GZMB; H2-AB1; HLA-DRA; H2-AA; KIR2DL3
    Viral myocarditis EIF4G2; ITGB2; HLA-A; CD40LG; HLA-DPA1; ACTG1; CASP8; HLA-C; ITGAL; CCND1

    cd28 has several biochemical functions, for example, SH3/SH2 adaptor activity, coreceptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd28 itself. We selected most functions cd28 had, and list some proteins which have the same functions with cd28. You can find most of the proteins on our site.

    Function Related Protein
    SH3/SH2 adaptor activity CHN1; SH2D3A; GRAP; KHDRBS1; SH3BP2; CRK; NCK2; ARHGAP1; GRB2; CD28
    coreceptor activity CD80; CD86; CXCR7B; RGMD; CD8A; PVRL2; TGFBR3; RAMP2; TMIGD2; CCR8
    identical protein binding NCAM1; TRIM21; DAPK3; PARK2; INS; APLP1; PCM1; MAP1S; SEPT7; IGF2R
    protease binding HSPA6; TP53; LRP1; CSTA; CD70; SERPINE1; BRCA2; SERPINA5; INS; ECM1
    protein binding MAPK3; SFRP1; GRM2; RUSC1; EHD1; RAB11FIP3; ADAMTS10; RNF24; MARCH2; SEMA4D

    cd28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd28 here. Most of them are supplied by our site. Hope this information will be useful for your research of cd28.

    PIK3R1; GRAP2; CD80; PIK3R1; Pik3r1; GRB2; PRKCQ

    Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
    Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).

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