Recombinant Human CD28 Protein, DDK/His-tagged
| Cat.No. : | CD28-181H |
| Product Overview : | Recombinant Human CD28(Asn19-Pro152) fused with DDK/His tag at C-terminal was expressed in HEK293. |
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| Description : | The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His&Flag |
| Form : | 1 x PBS, pH7.4, 10% glycerol. |
| Molecular Mass : | 18 kDa |
| Protein length : | Asn19-Pro152 |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name : | CD28 CD28 molecule [ Homo sapiens ] |
| Official Symbol : | CD28 |
| Synonyms : | CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290; |
| Gene ID : | 940 |
| mRNA Refseq : | NM_006139 |
| Protein Refseq : | NP_006130 |
| MIM : | 186760 |
| UniProt ID : | P10747 |
Products Types
| ◆ Recombinant Protein | ||
| CD28-0773H | Recombinant Human CD28 Protein, His-Flag-StrepII-Tagged | +Inquiry |
| CD28-624M | Recombinant Mouse CD28 Protein | +Inquiry |
| Cd28-28M | Recombinant Mouse CD28 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
| CD28-4376H | Recombinant Human CD28 Protein, His (Fc)-Avi-tagged | +Inquiry |
| CD28-1204C | Active Recombinant Cynomolgus CD28 protein(Met1-Pro152), hFc-tagged | +Inquiry |
| ◆ Lysates | ||
| CD28-2002MCL | Recombinant Mouse CD28 cell lysate | +Inquiry |
| CD28-2013HCL | Recombinant Human CD28 cell lysate | +Inquiry |
| ◆ Assay kits | ||
| Kit-1705 | CD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIts unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.
Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.
the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.
Q&As (5)
Ask a questionCD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.
Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.
CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.
CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.
Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.
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