Active Recombinant Human FGF7 Protein, Pre-aliquoted

• Cat.No.: FGF7-18H
• Product Overview: Recombinant Human FGF7 Protein, Cys32 - Thr194, with an N-terminal Met, was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
• Source: E. coli
• Species: Human
• Bio-activity: Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cells. The ED50 for this effect is 6-60 ng/mL. None
• Molecular Mass: Predicted Molecular Mass:19 kDa
  SDS-PAGE:
• Protein length: Cys32-Thr194, with an N-terminal Met
• N-terminal Sequence Analysis: Met
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: > 97% by SDS-PAGE under reducing conditions and visualized by silver stain.
• Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 6 months from date of receipt at room temperature.
  • 12 months from date of receipt at 2-8 centigrade as supplied.
  • 1 month at 2-8 centigrade under sterile conditions after reconstitution.
  • 3 months at -20 to -80 centigrade under sterile conditions after reconstitution.
• Reconstitution: For a stock solution, reconstitute at 100 μg/mL in sterile PBS, or simply roll Pre-aliquoted directly into cell culture medium for immediate use.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: FGF7 fibroblast growth factor 7 [ Homo sapiens (human) ]
• Official Symbol: FGF7
• Synonyms: FGF7; fibroblast growth factor 7; KGF; HBGF-7; fibroblast growth factor 7; FGF-7; heparin-binding growth factor 7; keratinocyte growth factor
• Gene ID: 2252
• mRNA Refseq: NM_002009
• Protein Refseq: NP_002000
• MIM: 148180
• UniProt ID: P21781

Reviews

03/21/2022

I highly recommend the FGF7 Protein to fellow researchers seeking a high-quality protein that not only meets their experimental requirements but is also accompanied by exceptional technical support.

05/01/2021

The FGF7 Protein's consistent stability and robust performance make it an indispensable tool for studying its multifaceted roles and mechanisms within vital biochemical pathways and cellular processes.

10/01/2017

What truly distinguishes the FGF7 Protein is the unparalleled technical support provided by the manufacturer.

Q&As

How does FGF7 aid in tissue repair?

FGF7 stimulates the proliferation and migration of epithelial cells, which are crucial for repairing damaged tissues.

Are there any side effects associated with FGF7 treatment?

Side effects are generally mild, such as local irritation at the site of application, but comprehensive studies are ongoing.

Can FGF7 be used in regenerative medicine?

Yes, FGF7 is being explored for its potential in regenerating tissues and promoting healing in various medical fields.

How is FGF7 administered in clinical settings?

FGF7 can be administered topically or via injection, depending on the specific condition being treated.

Is FGF7 used in dermatology?

Yes, FGF7 has been investigated for its potential in treating skin disorders, including conditions like psoriasis and atopic dermatitis.