Active Recombinant Human FGF7 Protein

Cat.No. : FGF7-90H
Product Overview : Recombinant Human FGF7 Protein without tag was expressed in E. coli.
  • Specification
  • Gene Information
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Description : Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation. FGF-7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFR2-IIIb). The mitogenic activity of FGF-7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells. FGF-7 expression is upregulated after acute and chronic injury, suggesting that FGF-7 functions during the healing of injured epithelial cells. FGF-7 also induces the formation of the apical ectodermal ridge during limb development.
Source : E. coli
Species : Human
Bio-activity : 4MBr-5 cell proliferation, ≤60 ng/mL; ≥1.7 x 10^4 units/mg
Molecular Mass : Monomer, 19 kDa (164 aa)
AA Sequence : MCNDMTPEQMATNVNCSSPERHTRS YDYMEGGDIRVRRLFCRTQWYLRID KRGKVKGTQEMKNNYNIMEIRTVAV GIVAIKGVESEFYLAMNKEGKLYAK KECNEDCNFKELILENHYNTYASAK WTHNGGEMFVALNQKGIPVRGKKTK KEQKTAHFLPMAIT
Endotoxin : ≤1 EUs/μg, Kinetic LAL
Purity : ≥90%, Reducing and Non-Reducing SDS PAGE
Stability : 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
1 month when stored at 4 centigrade after reconstituting as directed.
3 months when stored at -20 to -80 centigrade after reconstituting as directed.
Storage : Storage Prior to Reconstitution: -20 centigrade
Storage Buffer : Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 100 mM sodium chloride, pH 7.5
Reconstitution : Sterile water at 0.1 mg/mL
Shipping : Room temperature
Instructions : Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.
Gene Name : FGF7 fibroblast growth factor 7 [ Homo sapiens (human) ]
Official Symbol : FGF7
Synonyms : FGF7; fibroblast growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); keratinocyte growth factor; KGF; FGF-7; heparin-binding growth factor 7; HBGF-7;
Gene ID : 2252
mRNA Refseq : NM_002009
Protein Refseq : NP_002000
MIM : 148180
UniProt ID : P21781

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does FGF7 aid in tissue repair? 11/12/2022

FGF7 stimulates the proliferation and migration of epithelial cells, which are crucial for repairing damaged tissues.

Are there any side effects associated with FGF7 treatment? 05/09/2019

Side effects are generally mild, such as local irritation at the site of application, but comprehensive studies are ongoing.

Can FGF7 be used in regenerative medicine? 06/16/2018

Yes, FGF7 is being explored for its potential in regenerating tissues and promoting healing in various medical fields.

How is FGF7 administered in clinical settings? 08/01/2017

FGF7 can be administered topically or via injection, depending on the specific condition being treated.

Is FGF7 used in dermatology? 02/13/2016

Yes, FGF7 has been investigated for its potential in treating skin disorders, including conditions like psoriasis and atopic dermatitis.

Customer Reviews (3)

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Reviews
03/21/2022

    I highly recommend the FGF7 Protein to fellow researchers seeking a high-quality protein that not only meets their experimental requirements but is also accompanied by exceptional technical support.

    05/01/2021

      The FGF7 Protein's consistent stability and robust performance make it an indispensable tool for studying its multifaceted roles and mechanisms within vital biochemical pathways and cellular processes.

      10/01/2017

        What truly distinguishes the FGF7 Protein is the unparalleled technical support provided by the manufacturer.

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