Active Recombinant Human IL17F Protein, Animal Free
|Product Overview :||Recombinant Human IL17F Protein without tag was expressed in Human cells.
Animal Free and Xeno Free
- Gene Information
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|Description :||IL-17F is a member of IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F is a homodimer of two 133 amino acid chains that are secreted by activated CD4+ T cells and activated monocytes. The biological activities mediated by IL-17F are similar to those of IL-17. IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony stimulating factor. It can also regulate cartilage matrix turnover, stimulate PBMC and T cell proliferation, and inhibit angiogenesis.|
|Source :||Human cells|
|Bio-activity :||The activity was measured by its ability to induce IL-6 expression in the NHDF adult fibroblasts.|
|Molecular Mass :||38 kDa|
|Endotoxin :||<0.5 EU/ μg|
|Purity :||High Purity, >95% by SDS-PAGE|
|Stability :||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.|
|Storage Buffer :||Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein|
|Reconstitution :||Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Gene Name :||IL17F interleukin 17F [ Homo sapiens (human) ]|
|Official Symbol :||IL17F|
|Synonyms :||IL17F; interleukin 17F; interleukin-17F; IL 17F; ML 1; ML1; IL-24; cytokine ML-1; mutant IL-17F; interleukin-24; ML-1; CANDF6; IL-17F;|
|Gene ID :||112744|
|mRNA Refseq :||NM_052872|
|Protein Refseq :||NP_443104|
|UniProt ID :||Q96PD4|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
Tumor xenografts, immune cell infiltration analysis, and therapeutic antibody testing assess IL17F's role in cancer.
Neutrophil chemotaxis assays, in vivo neutrophil tracking, and immune cell activation analysis explore IL17F's impact on neutrophil functions.
Genetic knockout models, functional assays, and gene expression analyses distinguish IL17F's unique roles.
Microbiota composition analysis, germ-free models, and immune cell profiling investigate IL17F-microbiota interactions.
Animal disease models, patient samples, and immunological assays elucidate IL17F's contribution to autoimmune diseases.
Co-immunoprecipitation, fluorescence resonance energy transfer (FRET), and pathway-specific assays elucidate IL17F's heterodimerization and signaling.
Comparative cytokine profiling, inflammatory assays, and pathway analysis dissect IL17F's interplay with other immune mediators.
Allergen challenges, inflammatory disease models, and gene expression profiling probe IL17F's involvement in chronic conditions.
Epithelial barrier permeability assays, tissue section analysis, and cell culture models study IL17F's effects on barrier integrity.
Wound healing assays, tissue regeneration models, and histological analyses examine IL17F's effects on tissue repair.
Customer Reviews (3)Write a review
High specificity. -
Good for receptor studies. -
Potent in anti-bacterial assays. -
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