• Official Full Name

    interleukin 17F

  • Background

    The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
  • Synonyms

    IL17F; interleukin 17F; ML1; ML-1; CANDF6; IL-17F; interleukin-17F; cytokine ML-1;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Bovine
    • Chicken
    • Cynomolgus
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293F
    • Human Cell
    • Human cells
    • Insect Cell
    • Mammalian Cell
    • Yeast
    • Tag :
    • Fc
    • His
    • His (Fc)
    • Avi
    • His(C
    • ter)
    • Met
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Bovine IL17F-57B Recombinant Bovine IL-17F Yeast N/A
    Chicken IL17F-6030C Recombinant Chicken IL17F Mammalian Cell His
    Cynomolgus IL17F-0298C Recombinant Cynomolgus IL17F protein, His-tagged HEK293 His
    Human IL17F-367H Active Recombinant Human Interleukin 17F, HIgG1 Fc-tagged CHO Fc
    Human IL17F-377H Recombinant Human IL17F protein, His-tagged HEK293 His
    Human IL17F-365H Active Recombinant Human Interleukin 17F, HIgG1 Fc-tagged CHO Fc
    Human IL17F-307H Recombinant Human IL17F protein, His-tagged HEK293 His
    Human IL17F-366H Active Recombinant Human Interleukin 17F, HIgG1 Fc-tagged, mutant CHO Fc
    Human IL17F-14156H Recombinant Human IL17F, His-tagged E.coli His
    Human IL17F-377HB Recombinant Human IL17F protein, His-tagged, Biotinylated HEK293 His
    Human IL17F-28H Recombinant Human IL17F Protein, Animal Free Human cells
    Human IL17F-261H Recombinant Human interleukin 17F, His-tagged E.coli His
    Human IL17F-114H Active Recombinant Human Interleukin 17F HEK293 N/A
    Human IL17F-099I Recombinant Human IL17F Protein (133 aa) E.coli
    Human IL17F-509H Active Recombinant Human IL17F HEK293 N/A
    Human IL17F-4332H Recombinant Human IL17F Protein Yeast N/A
    Human IL17F-434H Recombinant Human IL17F protein E.coli N/A
    Human IL17F-151H Recombinant Active Human IL17F Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human IL17F-2045HCL Recombinant Human IL17F cell lysate Human Cell N/A
    Human IL17F-143H Recombinant Human IL17F Protein E.coli
    Human IL17F-129H Active Recombinant Human IL17F protein E.coli N/A
    Human IL17F-36H Recombinant Human IL17F protein E.coli N/A
    Human IL17F-964H Recombinant Human IL17F protein, His-Avi-tagged HEK293 His-Avi
    Human IL17F-1009H Recombinant Human IL17F Protein, His-tagged HEK293F N-His
    Human IL17F-956HB Recombinant Human IL17F protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Human IL17F-01H Recombinant Human IL17F Protein, His-Tagged Insect Cell His
    Human IL17F-139H Recombinant Human IL17F Protein E.coli
    Mouse IL17F-144M Recombinant Mouse IL17F Protein E.coli
    Mouse Il17f-01M Active Recombinant Mouse Il17f Protein, His-Tagged E.coli His
    Mouse Il17f-152M Recombinant Active Mouse IL17F Protein, His-tagged(C-ter) E.coli His(C-ter)
    Mouse Il17f-403M Active Recombinant Mouse Il17f, Met-tagged E.coli Met
    Mouse Il17f-8338M Recombinant Mouse Il17f E.coli N/A
    Mouse Il17f-497M Active Recombinant Mouse Interleukin 17F E.coli N/A
    Mouse Il17f-964M Recombinant Mouse Il17f Protein, His-tagged HEK293 His
    Mouse IL17F-1939M Recombinant Mouse IL17F protein E.coli N/A
    Mouse Il17f-142M Recombinant Mouse Il17f Protein E.coli
    Mouse Il17f-143M Recombinant Mouse Il17f Protein E.coli
    Mouse Il17f-1665M Recombinant Mouse Il17f Protein, His-tagged E.coli N-His
    Rabbit IL17F-4333R Recombinant Rabbit IL17F Protein Yeast N/A
    Rat IL17F-2684R Recombinant Rat IL17F Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat Il17f-642R Active Recombinant Rat Il17f E.coli N/A
    Rat Il17f-498R Active Recombinant Rat Interleukin-17F E.coli N/A
    Rat Il17f-1118R Active Recombinant Rat Il17f Protein, His-tagged Insect Cell His
    Rat IL17F-2684R-B Recombinant Rat IL17F Protein Pre-coupled Magnetic Beads HEK293
    Rat Il17f-204R Recombinant Rat Interleukin 17F E.coli N/A
    Rat IL17F-145R Recombinant Rat IL17F Protein E.coli
    Rat IL17F-3029R Recombinant Rat IL17F Protein Mammalian Cell His
    Rhesus Macaque IL17F-2056R-B Recombinant Rhesus Macaque IL17F Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque IL17F-2056R Recombinant Rhesus Macaque IL17F Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque IL17F-2235R Recombinant Rhesus monkey IL17F Protein, His-tagged Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Il17f Related Articles
    • Il17f Related Gene Family
    • Il17f Related Research Area

    Il17f involved in several pathways and played different roles in them. We selected most pathways Il17f participated on our site, such as IL17 signaling pathway, IL23-mediated signaling events, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with Il17f were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    IL17 signaling pathwayTRAF3IP2;IL17F;IL17RE;IL17C;IL17RC
    IL23-mediated signaling eventsIL24;IL17F;IL23R
    Inflammatory bowel disease (IBD)IL23R;HLA-DRA;TNF;IL17A;SMAD3;HLA-DOA;IFNGR1;IL17F;HLA-DQA2

    Il17f has several biochemical functions, for example, cytokine activity, cytokine binding, cytokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il17f itself. We selected most functions Il17f had, and list some proteins which have the same functions with Il17f. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activityGM13288;IL23;CCL20B;GDF6B;LFT2;MIF;SPP1;C1QTNF4;BMP4
    cytokine bindingNRP2;CSF1RA;KIT;TNFRSF11A;CRLF1;CD74;CHRD;NOG;CSF1R
    cytokine receptor bindingIFNPHI4;IFNA12;IFNA21;IL17A/F3;IL17A/F1;MIF;IFNW1;IFNA5;IFNPHI2
    protein bindingKLRB1B;TIA1;MED29;TFR2;MOB3C;ATP6V1B2;ZNF436;FCN3;DUSP9
    protein homodimerization activitySMAD2;RNF40;SYNE1;KIAA1804;BMP4;VPS24;ABCD2;Il6ra;APOA1BP

    Il17f has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il17f here. Most of them are supplied by our site. Hope this information will be useful for your research of Il17f.


    McDermott, AJ; Higdon, KE; et al. The role of Gr-1(+) cells and tumour necrosis factor-alpha signalling during Clostridium difficile colitis in mice. IMMUNOLOGY 144:704-716(2015).
    Thompson-Crispi, KA; Sargolzaei, M; et al. A genome-wide association study of immune response traits in Canadian Holstein cattle. BMC GENOMICS 15:-(2014).
    • Q&As
    • Reviews

    Q&As (10)

    Ask a question
    What techniques are used to assess IL17F's involvement in cancer development and its potential as a therapeutic target? 03/05/2022

    Tumor xenografts, immune cell infiltration analysis, and therapeutic antibody testing assess IL17F's role in cancer.

    What methodologies are employed to explore IL17F's role in promoting neutrophil recruitment and activation at mucosal sites? 04/05/2021

    Neutrophil chemotaxis assays, in vivo neutrophil tracking, and immune cell activation analysis explore IL17F's impact on neutrophil functions.

    How do researchers differentiate the functional roles of IL17F from other IL17 family members in immune responses? 02/04/2021

    Genetic knockout models, functional assays, and gene expression analyses distinguish IL17F's unique roles.

    How is the interplay between IL17F and gut microbiota investigated, and what are the implications for intestinal health? 07/21/2020

    Microbiota composition analysis, germ-free models, and immune cell profiling investigate IL17F-microbiota interactions.

    Could you elaborate on the strategies employed to investigate IL17F's contribution to autoimmune diseases using experimental models and patient samples? 05/27/2020

    Animal disease models, patient samples, and immunological assays elucidate IL17F's contribution to autoimmune diseases.

    What experimental techniques are utilized to dissect the complex heterodimerization of IL17F with IL17A and its impact on signaling pathways? 04/09/2020

    Co-immunoprecipitation, fluorescence resonance energy transfer (FRET), and pathway-specific assays elucidate IL17F's heterodimerization and signaling.

    How do researchers investigate the potential synergistic or antagonistic effects of IL17F on tissue inflammation in comparison to other cytokines? 12/21/2019

    Comparative cytokine profiling, inflammatory assays, and pathway analysis dissect IL17F's interplay with other immune mediators.

    What molecular approaches are used to study IL17F's involvement in chronic inflammatory conditions, such as asthma and inflammatory bowel diseases? 03/31/2018

    Allergen challenges, inflammatory disease models, and gene expression profiling probe IL17F's involvement in chronic conditions.

    Can you explain the experimental designs used to study the impact of IL17F on barrier function in epithelial tissues? 06/24/2017

    Epithelial barrier permeability assays, tissue section analysis, and cell culture models study IL17F's effects on barrier integrity.

    How do researchers explore the effects of IL17F modulation on tissue repair and regeneration in experimental models? 03/21/2017

    Wound healing assays, tissue regeneration models, and histological analyses examine IL17F's effects on tissue repair.

    Customer Reviews (3)

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      High specificity. -


        Good for receptor studies. -


          Potent in anti-bacterial assays. -

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