Il17f
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Official Full Name
interleukin 17F
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Background
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008] -
Synonyms
IL17F; interleukin 17F; ML1; ML-1; CANDF6; IL-17F; interleukin-17F; cytokine ML-1;
- Involved Pathway
- Protein Function
- Interacting Protein
- Il17f Related Articles
- Il17f Related Gene Family
- Il17f Related Research Area
Il17f involved in several pathways and played different roles in them. We selected most pathways Il17f participated on our site, such as IL17 signaling pathway, IL23-mediated signaling events, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with Il17f were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| IL17 signaling pathway | TRAF3IP2;IL17F;IL17RE;IL17C;IL17RC |
| IL23-mediated signaling events | IL24;IL17F;IL23R |
| Inflammatory bowel disease (IBD) | IL23R;HLA-DRA;TNF;IL17A;SMAD3;HLA-DOA;IFNGR1;IL17F;HLA-DQA2 |
Il17f has several biochemical functions, for example, cytokine activity, cytokine binding, cytokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il17f itself. We selected most functions Il17f had, and list some proteins which have the same functions with Il17f. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | GM13288;IL23;CCL20B;GDF6B;LFT2;MIF;SPP1;C1QTNF4;BMP4 |
| cytokine binding | NRP2;CSF1RA;KIT;TNFRSF11A;CRLF1;CD74;CHRD;NOG;CSF1R |
| cytokine receptor binding | IFNPHI4;IFNA12;IFNA21;IL17A/F3;IL17A/F1;MIF;IFNW1;IFNA5;IFNPHI2 |
| protein binding | KLRB1B;TIA1;MED29;TFR2;MOB3C;ATP6V1B2;ZNF436;FCN3;DUSP9 |
| protein homodimerization activity | SMAD2;RNF40;SYNE1;KIAA1804;BMP4;VPS24;ABCD2;Il6ra;APOA1BP |
Il17f has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il17f here. Most of them are supplied by our site. Hope this information will be useful for your research of Il17f.
FLJ13057
- Q&As
- Reviews
Q&As (10)
Ask a questionTumor xenografts, immune cell infiltration analysis, and therapeutic antibody testing assess IL17F's role in cancer.
Neutrophil chemotaxis assays, in vivo neutrophil tracking, and immune cell activation analysis explore IL17F's impact on neutrophil functions.
Genetic knockout models, functional assays, and gene expression analyses distinguish IL17F's unique roles.
Microbiota composition analysis, germ-free models, and immune cell profiling investigate IL17F-microbiota interactions.
Animal disease models, patient samples, and immunological assays elucidate IL17F's contribution to autoimmune diseases.
Co-immunoprecipitation, fluorescence resonance energy transfer (FRET), and pathway-specific assays elucidate IL17F's heterodimerization and signaling.
Comparative cytokine profiling, inflammatory assays, and pathway analysis dissect IL17F's interplay with other immune mediators.
Allergen challenges, inflammatory disease models, and gene expression profiling probe IL17F's involvement in chronic conditions.
Epithelial barrier permeability assays, tissue section analysis, and cell culture models study IL17F's effects on barrier integrity.
Wound healing assays, tissue regeneration models, and histological analyses examine IL17F's effects on tissue repair.
Customer Reviews (3)
Write a reviewHigh specificity. -
Good for receptor studies. -
Potent in anti-bacterial assays. -
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