Active Recombinant Human IL22 Protein
|Product Overview :||Recombinant Human IL22 Protein without tag was expressed in E. coli.|
- Gene Information
- Related Products
|Description :||Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains. IL-22 is a potent mediator of cellular inflammatory responses.|
|Source :||E. coli|
|Bio-activity :||No biological activity data is available at this time.|
|Molecular Mass :||Dimer, 16.9/33.8 kDa (147/294 aa)|
|AA Sequence :||MAPISSHCRLDKSNFQQPYITNRTF MLAKEASLADNNTDVRLIGEKLFHG VSMSERCYLMKQVLNFTLEEVLFPQ SDRFQPYMQEVVPFLARLSNRLSTC HIEGDDLHIQRNVQKLKDTVKKLGE SGEIKAIGELDLLFMSLRNACI|
|Endotoxin :||≤1 EUs/μg, Kinetic LAL|
|Purity :||≥95%, Reducing and Non-Reducing SDS PAGE|
|Stability :||12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
1 month when stored at 4 centigrade after reconstituting as directed.
3 months when stored at -20 to -80 centigrade after reconstituting as directed.
|Storage :||Storage Prior to Reconstitution: -20 centigrade|
|Storage Buffer :||Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium citrate, pH 3.0|
|Reconstitution :||Sterile water at 0.1 mg/mL|
|Shipping :||Room temperature|
|Instructions :||Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.|
|Gene Name :||IL22 interleukin 22 [ Homo sapiens (human) ]|
|Official Symbol :||IL22|
|Synonyms :||IL22; interleukin 22; interleukin-22; IL 10 related T cell derived inducible factor; IL 21; IL 22; IL D110; IL TIF; ILTIF; MGC79382; MGC79384; TIFa; TIFIL 23; zcyto18; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL-22; IL-TIF; IL-D110; TIFIL-23;|
|Gene ID :||50616|
|mRNA Refseq :||NM_020525|
|Protein Refseq :||NP_065386|
|UniProt ID :||Q9GZX6|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
IL22 enhances gut epithelial repair mechanisms.
IL22 activates STAT3 to modulate downstream targets.
IL22 interacts synergistically with IL-17 during inflammation.
IL22 is involved in the pathogenesis of autoimmune diseases like Crohn's.
IL22 is implicated in metabolic syndrome by affecting insulin sensitivity.
IL22 expression is upregulated in psoriasis.
IL22 expression is upregulated during viral infections like Hepatitis C.
IL22 contributes to anti-tumor immunity by activating NK cells.
IL22 promotes Th22 cell differentiation.
IL22 polymorphisms affect its binding affinity and signaling.
Customer Reviews (3)Write a review
High specificity. -
Good for Th17 differentiation. -
Effective in gut repair assays. -
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