Active Recombinant Mouse Interleukin 22, MIgG2a Fc-tagged
| Cat.No. : | IL22-601M |
| Product Overview : | The extracellular domain of mouse IL-22 (NP_058667.1)(Leu34-Val179) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell. |
- Specification
- Gene Information
- Related Products
| Source : | CHO cells |
| Species : | Mouse |
| Tag : | MIgG2a Fc-tagged |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | The Biological Activity was determined by the ability to activiate STAT following receptor ligand interaction. |
| Molecular Mass : | 46 KDa |
| AA Sequence : | Leu34-Val179 |
| Endotoxin : | ≤0.1 EU/μg as determined by LAL test. |
| Purity : | ≥98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Gene Name : | Il22 interleukin 22 [ Mus musculus ] |
| Official Symbol : | IL22 |
| Synonyms : | IL22; interleukin 22; interleukin-22; ILTIF alpha; IL-TIF alpha; interleukin-22a; IL-10-related T-cell-derived-inducible factor; interleukin 10-related T cell-derived inducible factor; IL-22; Iltif; IL-22a; ILTIFa; MGC129416; MGC129417; |
| Gene ID : | 50929 |
| mRNA Refseq : | NM_016971 |
| Protein Refseq : | NP_058667 |
| Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
| Function : | cytokine activity; protein binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionIL22 enhances gut epithelial repair mechanisms.
IL22 activates STAT3 to modulate downstream targets.
IL22 interacts synergistically with IL-17 during inflammation.
IL22 is involved in the pathogenesis of autoimmune diseases like Crohn's.
IL22 is implicated in metabolic syndrome by affecting insulin sensitivity.
IL22 expression is upregulated in psoriasis.
IL22 expression is upregulated during viral infections like Hepatitis C.
IL22 contributes to anti-tumor immunity by activating NK cells.
IL22 promotes Th22 cell differentiation.
IL22 polymorphisms affect its binding affinity and signaling.
Customer Reviews (3)
Write a reviewHigh specificity. -
Good for Th17 differentiation. -
Effective in gut repair assays. -
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