Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human SRC Protein, GST-tagged

Cat.No. : SRC-004H
Product Overview : Active recombinant full length human SRC Protein (1-536) with a N-terminal GST tag was expressed in insect cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Source : Insect cell
Species : Human
Tag : GST
Bio-activity : Tris buffered solution containing MgCl2, 10μM ATP, 10 μg Poly-Glu, Tyr 4:1 substrate and 30 ng of Src. Incubate at 30 centigrade for 45 min, and measure ATP via luminescent assay. Luminescence is inversely correlated to kinase activity.
Molecular Mass : 86 kDa
Protein length : 1-536
Purity : ≥60% as determined by SDS-PAGE
Applications : Enzyme assay
Stability : ≥ 6 months
Storage : At -80 centigrade.
Storage Buffer : 25 mM Tris-HCl, pH 8.0, with 69 mM sodium chloride, 1.35 mM potassium chloride, 0.025% Tween-20, 125 mM imidazole, 50% glycerol, and 3 mM DTT
Gene Name : SRC SRC proto-oncogene, non-receptor tyrosine kinase [ Homo sapiens (human) ]
Official Symbol : SRC
Synonyms : SRC; SRC proto-oncogene, non-receptor tyrosine kinase; ASV; SRC1; THC6; c-SRC; p60-Src; proto-oncogene tyrosine-protein kinase Src; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; EC
Gene ID : 6714
mRNA Refseq : NM_005417
Protein Refseq : NP_005408
MIM : 190090
UniProt ID : P12931

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.



Inquiry Basket



Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends