Active Recombinant Mouse Src protein(Met1-Leu535), His&GST-tagged
Cat.No. : | Src-907M |
Product Overview : | Recombinant Mouse SRC (NP_001020566.111) (Met 1-Leu 535) was expressed in Insect Cells, fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
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Source : | Insect Cells |
Species : | Mouse |
Tag : | His&GST |
Protein length : | Met1-Leu535 |
Form : | Supplied as sterile 20mM Tris, 500mM NaCl, 10% gly, pH 8.0. |
Bio-activity : | 1. The specific activity was determined to be >80 nmol/min/mg using poly [Glu, Tyr] 4:1 as substRate. 2. Measured by its binding ability in a functional ELISA. Immobilized recombinant Mouse SRC at 2 μg/ml (100 μl/well) can bind biotinylated human PTPRA (aa 174-793) with a linear range of 0.032-0.8 μg/ml. |
Molecular Mass : | The recombinant mouse SRC/GST chimera consists of 773 amino acids and has a calculated molecular mass of 87.7 kDa. It migRates as an approximately 80 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Src Rous sarcoma oncogene [ Mus musculus ] |
Official Symbol : | Src |
Synonyms : | SRC; Rous sarcoma oncogene; neuronal proto-oncogene tyrosine-protein kinase Src; p60-Src; proto-oncogene c-Src; AW259666; pp60c-src; |
Gene ID : | 20779 |
mRNA Refseq : | NM_001025395 |
Protein Refseq : | NP_001020566 |
Products Types
◆ Recombinant Protein | ||
SRC-0403H | Recombinant Human SRC Protein (G2-L536), His/Flag tagged | +Inquiry |
SRC-2747H | Recombinant Human SRC Protein, MYC/DDK-tagged | +Inquiry |
Src-6122M | Recombinant Mouse Src Protein, Myc/DDK-tagged | +Inquiry |
SRC-2094H | Recombinant Human SRC Protein, His (Fc)-Avi-tagged | +Inquiry |
SRC-4276R | Recombinant Rhesus Macaque SRC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
SRC-29697TH | Native Human SRC | +Inquiry |
◆ Lysates | ||
SRC-487HCL | Recombinant Human SRC cell lysate | +Inquiry |
SRC-585MCL | Recombinant Mouse SRC cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionChanges in SRC expression or kinase activity can lead to drug resistance in cancer treatment.
SRC regulates cell proliferation and survival through its kinase activity, influencing various signaling pathways.
SRC is involved in bone remodeling, regulating osteoclast activity and bone resorption.
SRC plays a crucial role in cancer progression, particularly in enhancing metastatic potential of tumor cells.
SRC influences key cellular signaling pathways like Ras/MAPK and PI3K/Akt, affecting cell growth and survival.
SRC modulates cellular adhesion and migration, playing a role in tissue repair and cancer metastasis.
SRC inhibition is a target in cancer therapy, potentially reducing tumor growth and metastasis.
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