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Native Human SRC
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Cat.No. : | SRC-29697TH Optional Service: Optional requirements on this protein |
Product Overview : | Fusion protein, corresponding to amino acids 84-145 of Human Src and proprietary protein, approximately 33kDa. |
Description : | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
Source : | E. coli |
Form : | Lyophilised:Reconstitute within H2O bid. |
Purity : | Immunogen affinity purified |
Storage buffer : | Preservative: NoneConstituents: 50mM Potassium phosphate, 20mM Sodium chloride, pH 6.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain. |
Gene Name : | SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [ Homo sapiens ] |
Official Symbol : | SRC |
Synonyms : | SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); SRC1, v src avian sarcoma (Schmidt Ruppin A 2) viral oncogene homolog; proto-oncogene tyrosine-protein kinase Src; ASV; c src; |
Gene ID : | 6714 |
mRNA Refseq : | NM_005417 |
Protein Refseq : | NP_005408 |
MIM : | 190090 |
Uniprot ID : | P12931 |
Chromosome Location : | 20q12-q13 |
Pathway : | ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem; |
Function : | ATP binding; SH2 domain binding; SH3/SH2 adaptor activity; ephrin receptor binding; heme binding; |
◆ Recombinant Protein
SRC-004H | Recombinant Human SRC Protein, GST-tagged | +Inquiry |
Src-1367M | Recombinant Mus musculus Src Protein (V85-L535), His-tagged | +Inquiry |
SRC-2747H | Recombinant Human SRC Protein, MYC/DDK-tagged | +Inquiry |
Src-1368M | Recombinant Mus musculus Src Protein (V85-L535) | +Inquiry |
Src-6122M | Recombinant Mouse Src Protein, Myc/DDK-tagged | +Inquiry |
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◆ Lysates
SRC-585MCL | Recombinant Mouse SRC cell lysate | +Inquiry |
SRC-487HCL | Recombinant Human SRC cell lysate | +Inquiry |
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