Native Human SRC SRC-29697TH

Native Human SRC

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Native Human SRC

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Cat.No. : SRC-29697TH Optional Service: Optional requirements on this protein
Product Overview : Fusion protein, corresponding to amino acids 84-145 of Human Src and proprietary protein, approximately 33kDa.
Description : This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Source : E. coli
Form : Lyophilised:Reconstitute within H2O bid.
Purity : Immunogen affinity purified
Storage buffer : Preservative: NoneConstituents: 50mM Potassium phosphate, 20mM Sodium chloride, pH 6.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain.
Gene Name : SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [ Homo sapiens ]
Official Symbol : SRC
Synonyms : SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); SRC1, v src avian sarcoma (Schmidt Ruppin A 2) viral oncogene homolog; proto-oncogene tyrosine-protein kinase Src; ASV; c src;
Gene ID : 6714
mRNA Refseq : NM_005417
Protein Refseq : NP_005408
MIM : 190090
Uniprot ID : P12931
Chromosome Location : 20q12-q13
Pathway : ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem;
Function : ATP binding; SH2 domain binding; SH3/SH2 adaptor activity; ephrin receptor binding; heme binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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